DrugDomain logoDrugDomain

(7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL

P41145 — Kappa-type opioid receptor

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Attributes

UniProt ID
P41145
Protein Name
Kappa-type opioid receptor
Ligand Name
(7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL
DrugBank ID
DB00295
PDB Ligand Accession
MOI
ChEMBL ID
CHEMBL70
PubChem ID
5288826
InChIKey
BQJCRHHNABKAKU-KBQPJGBKSA-N
SMILES
CN1CCC23c4c5ccc(c4OC2C(C=CC3C1C5)O)O
Drug Action
agonist
Affinity Metrics
ki:4.4 nM
ic50:217 nM
ec50:330 nM