(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid
P43115 — Prostaglandin E2 receptor EP3 subtype
Attributes
UniProt ID
Protein Name
Prostaglandin E2 receptor EP3 subtype
Ligand Name
(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid
DrugBank ID
PDB Ligand Accession
ChEMBL ID
PubChem ID
InChIKey
XEYBRNLFEZDVAW-ARSRFYASSA-N
SMILES
CCCCCC(C=CC1C(CC(=O)C1CC=CCCCC(=O)O)O)O
Drug Action
agonist
Affinity Metrics
ki:0.33 nM
ic50:0.94 nM
ec50:2.5 nM