2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide

P43405 — Tyrosine-protein kinase SYK

Attributes

UniProt ID

Protein Name

Tyrosine-protein kinase SYK

Ligand Name

2-{2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl}-N-[(1S)-2-hydroxy-1-methylethyl]-4-methyl-1,3-thiazole-5-carboxamide

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

PEGXADGTBNRSGV-ZDUSSCGKSA-N

SMILES

Cc1cc(cc(c1)Nc2nccc(n2)c3nc(c(s3)C(=O)NC(C)CO)C)C

Drug Action

n/a

Affinity Metrics

ki:9 nM

ic50:6 nM