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2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide

P43405 — Tyrosine-protein kinase SYK

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Attributes

UniProt ID
P43405
Protein Name
Tyrosine-protein kinase SYK
Ligand Name
2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(3-methylphenyl)amino]pyrimidine-5-carboxamide
DrugBank ID
DB08361
PDB Ligand Accession
P5C
ChEMBL ID
CHEMBL1235110
PubChem ID
11493841
InChIKey
NZNTWOVDIXCHHS-LSDHHAIUSA-N
SMILES
Cc1cccc(c1)Nc2c(cnc(n2)NC3CCCCC3N)C(=O)N
Drug Action
inhibitor
Affinity Metrics
ic50:4 nM
ec50:2500 nM