(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one

P49137 — MAP kinase-activated protein kinase 2

Attributes

UniProt ID

Protein Name

MAP kinase-activated protein kinase 2

Ligand Name

(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

CMWRPDHVGMHLSZ-GFCCVEGCSA-N

SMILES

Cc1ccc(cn1)c2ccc3c(n2)ccc4c3c5c(s4)C(=O)NC(CN5)C

Drug Action

inhibitor

Affinity Metrics

ki:5 nM

ic50:2 nM