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(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRI AZA-CYCLOOCTADECOSINE-9-CARBONITRILE

P49354 — Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

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Attributes

UniProt ID
P49354
Protein Name
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Ligand Name
(20S)-19,20,21,22-TETRAHYDRO-19-OXO-5H-18,20-ETHANO-12,14-ETHENO-6,10-METHENO-18H-BENZ[D]IMIDAZO[4,3-K][1,6,9,12]OXATRI AZA-CYCLOOCTADECOSINE-9-CARBONITRILE
DrugBank ID
DB08674
PDB Ligand Accession
U49
ChEMBL ID
CHEMBL496879
PubChem ID
23646577
InChIKey
USPFJPDEADLGIG-HSZRJFAPSA-N
SMILES
c1cc2ccc3cc2c(c1)N4CCC(C4=O)NCc5cncn5Cc6ccc(c(c6)O3)C#N
Drug Action
n/a
Affinity Metrics
ic50:1.6 nM