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2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE

P52333 — Tyrosine-protein kinase JAK3

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Attributes

UniProt ID
P52333
Protein Name
Tyrosine-protein kinase JAK3
Ligand Name
2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE
DrugBank ID
DB04716
PDB Ligand Accession
IZA
ChEMBL ID
CHEMBL21156
PubChem ID
5494425
InChIKey
VNDWQCSOSCCWIP-UHFFFAOYSA-N
SMILES
CC(C)(C)c1[nH]c2c3c(c4cc(ccc4c2n1)F)C(=O)NC=C3
Drug Action
inhibitor
Affinity Metrics
ic50:5 nM