DrugDomain logoDrugDomain

(2S,3R,4R,5R)-N-(4-carbamoyl-2-methoxyphenyl)-2'-chloro-4-(3-chloro-2-fluorophenyl)-2-(2,2-dimethylpropyl)-5'-oxo-4',5'-dihydrospiro[pyrrolidine-3,6'-thieno[3,2-b]pyrrole]-5-carboxamide

P56273 — E3 ubiquitin-protein ligase Mdm2

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Attributes

UniProt ID
P56273
Protein Name
E3 ubiquitin-protein ligase Mdm2
Ligand Name
(2S,3R,4R,5R)-N-(4-carbamoyl-2-methoxyphenyl)-2'-chloro-4-(3-chloro-2-fluorophenyl)-2-(2,2-dimethylpropyl)-5'-oxo-4',5'-dihydrospiro[pyrrolidine-3,6'-thieno[3,2-b]pyrrole]-5-carboxamide
DrugBank ID
None
PDB Ligand Accession
20W
ChEMBL ID
CHEMBL3109040
PubChem ID
56649312
InChIKey
UOVSZRTTWLJPHE-HNXAPSNLSA-N
SMILES
CC(C)(C)CC1C2(c3c(cc(s3)Cl)NC2=O)C(C(N1)C(=O)Nc4ccc(cc4OC)C(=O)N)c5cccc(c5F)Cl
Drug Action
No data available
Affinity Metrics
No affinity data available