DrugDomain logoDrugDomain

(6R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one

P56817 — Beta-secretase 1

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Attributes

UniProt ID
P56817
Protein Name
Beta-secretase 1
Ligand Name
(6R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one
DrugBank ID
DB07519
PDB Ligand Accession
C27
ChEMBL ID
CHEMBL239857
PubChem ID
16040323
InChIKey
VDFBMQAUECXNKR-OAQYLSRUSA-N
SMILES
CC1(CC(=O)N(C(=N1)N)C)CCc2cccc(c2)c3cccc(c3)OC
Drug Action
n/a
Affinity Metrics
ic50:80 nM