DrugDomain logoDrugDomain

(2S,2'S)-N,N'-[(6,6'-difluoro-1H,1'H-2,2'-biindole-3,3'-diyl)bis{methanediyl[(2R,4S)-4-hydroxypyrrolidine-2,1-diyl][(2S)-1-oxobutane-1,2-diyl]}]bis[2-(methylamino)propanamide]

P98170 — E3 ubiquitin-protein ligase XIAP

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Attributes

UniProt ID
P98170
Protein Name
E3 ubiquitin-protein ligase XIAP
Ligand Name
(2S,2'S)-N,N'-[(6,6'-difluoro-1H,1'H-2,2'-biindole-3,3'-diyl)bis{methanediyl[(2R,4S)-4-hydroxypyrrolidine-2,1-diyl][(2S)-1-oxobutane-1,2-diyl]}]bis[2-(methylamino)propanamide]
DrugBank ID
DB11782
PDB Ligand Accession
GT6
ChEMBL ID
CHEMBL3039522
PubChem ID
49836020
InChIKey
PKWRMUKBEYJEIX-DXXQBUJASA-N
SMILES
CCC(C(=O)N1CC(CC1Cc2c3ccc(cc3[nH]c2c4c(c5ccc(cc5[nH]4)F)CC6CC(CN6C(=O)C(CC)NC(=O)C(C)NC)O)F)O)NC(=O)C(C)NC
Drug Action
modulator
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