DrugDomain logoDrugDomain

(4~{S})-5-(5-chloranyl-1-methyl-2-oxidanylidene-pyridin-3-yl)-4-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)-3-propan-2-yl-4~{H}-pyrrolo[3,4-d]imidazol-6-one

Q00987 — E3 ubiquitin-protein ligase Mdm2

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Attributes

UniProt ID
Q00987
Protein Name
E3 ubiquitin-protein ligase Mdm2
Ligand Name
(4~{S})-5-(5-chloranyl-1-methyl-2-oxidanylidene-pyridin-3-yl)-4-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)-3-propan-2-yl-4~{H}-pyrrolo[3,4-d]imidazol-6-one
DrugBank ID
DB16331
PDB Ligand Accession
9QW
ChEMBL ID
CHEMBL3653256
PubChem ID
71678098
InChIKey
AGBSXNCBIWWLHD-FQEVSTJZSA-N
SMILES
CC(C)n1c2c(nc1c3cnc(nc3OC)OC)C(=O)N(C2c4ccc(cc4)Cl)C5=CC(=CN(C5=O)C)Cl
Drug Action
inhibitor
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