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6-FLUORO-2-(2'-FLUORO-1,1'-BIPHENYL-4-YL)-3-METHYLQUINOLINE-4-CARBOXYLIC ACID

Q02127 — Dihydroorotate dehydrogenase , mitochondrial

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Attributes

UniProt ID
Q02127
Protein Name
Dihydroorotate dehydrogenase , mitochondrial
Ligand Name
6-FLUORO-2-(2'-FLUORO-1,1'-BIPHENYL-4-YL)-3-METHYLQUINOLINE-4-CARBOXYLIC ACID
DrugBank ID
DB03523
PDB Ligand Accession
BRF
ChEMBL ID
CHEMBL38434
PubChem ID
57030
InChIKey
PHEZJEYUWHETKO-UHFFFAOYSA-N
SMILES
Cc1c(c2cc(ccc2nc1c3ccc(cc3)c4ccccc4F)F)C(=O)O
Drug Action
modulator
Affinity Metrics
ki:12 nM
ic50:0.48 nM