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N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide

Q02750 — Dual specificity mitogen-activated protein kinase kinase 1

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Attributes

UniProt ID
Q02750
Protein Name
Dual specificity mitogen-activated protein kinase kinase 1
Ligand Name
N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
DrugBank ID
DB07101
PDB Ligand Accession
4BM
ChEMBL ID
CHEMBL507361
PubChem ID
9826528
InChIKey
SUDAHWBOROXANE-SECBINFHSA-N
SMILES
c1cc(c(cc1I)F)Nc2c(ccc(c2F)F)C(=O)NOCC(CO)O
Drug Action
n/a
Affinity Metrics
ic50:0.6 nM
kd:0.4 nM