6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

Q06187 — Tyrosine-protein kinase BTK

Attributes

UniProt ID

Protein Name

Tyrosine-protein kinase BTK

Ligand Name

6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

NHHQJBCNYHBUSI-UHFFFAOYSA-N

SMILES

CC1(C(=O)Nc2c(ccc(n2)Nc3c(cnc(n3)Nc4cc(c(c(c4)OC)OC)OC)F)O1)C

Drug Action

no_target_action

Affinity Metrics

kd:190 nM