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3-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-(DIFLUOROMETHOXY)BENZAMIDE

Q07343 — 3',5'-cyclic-AMP phosphodiesterase 4B

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Attributes

UniProt ID
Q07343
Protein Name
3',5'-cyclic-AMP phosphodiesterase 4B
Ligand Name
3-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-(DIFLUOROMETHOXY)BENZAMIDE
DrugBank ID
DB01656
PDB Ligand Accession
ROF
ChEMBL ID
CHEMBL193240
PubChem ID
449193
InChIKey
MNDBXUUTURYVHR-UHFFFAOYSA-N
SMILES
c1cc(c(cc1C(=O)Nc2c(cncc2Cl)Cl)OCC3CC3)OC(F)F
Drug Action
inhibitor
Affinity Metrics
ki:0.398107 nM
ic50:0.15 nM