DrugDomain logoDrugDomain

N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE

Q13882 — Protein-tyrosine kinase 6

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Attributes

UniProt ID
Q13882
Protein Name
Protein-tyrosine kinase 6
Ligand Name
N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE
DrugBank ID
DB01254
PDB Ligand Accession
1N1
ChEMBL ID
CHEMBL1421
PubChem ID
3062316
InChIKey
ZBNZXTGUTAYRHI-UHFFFAOYSA-N
SMILES
Cc1cccc(c1NC(=O)c2cnc(s2)Nc3cc(nc(n3)C)N4CCN(CC4)CCO)Cl
Drug Action
no_target_action
Affinity Metrics
ic50:5.3 nM
kd:7.8 nM