DrugDomain logoDrugDomain

4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide

Q14289 — Protein-tyrosine kinase 2-beta

← Back

Attributes

UniProt ID
Q14289
Protein Name
Protein-tyrosine kinase 2-beta
Ligand Name
4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide
DrugBank ID
DB08341
PDB Ligand Accession
P1E
ChEMBL ID
CHEMBL509485
PubChem ID
25920890
InChIKey
CAUFYHKGKDJMQG-HZPDHXFCSA-N
SMILES
CNS(=O)(=O)c1ccc(cc1)Nc2ncc(c(n2)NC3CCCC3N(C)C)C(F)(F)F
Drug Action
n/a
Affinity Metrics
ic50:88 nM