DrugDomain logoDrugDomain

N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE

Q15303 — Receptor tyrosine-protein kinase erbB-4

← Back

Attributes

UniProt ID
Q15303
Protein Name
Receptor tyrosine-protein kinase erbB-4
Ligand Name
N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE
DrugBank ID
DB01259
PDB Ligand Accession
FMM
ChEMBL ID
CHEMBL554
PubChem ID
208908
InChIKey
BCFGMOOMADDAQU-UHFFFAOYSA-N
SMILES
CS(=O)(=O)CCNCc1ccc(o1)c2ccc3c(c2)c(ncn3)Nc4ccc(c(c4)Cl)OCc5cccc(c5)F
Drug Action
no_target_action
Affinity Metrics
ic50:7.6 nM
kd:54 nM