DrugDomain logoDrugDomain

1-(2,6-DICHLOROPHENYL)-5-(2,4-DIFLUOROPHENYL)-7-PIPERIDIN-4-YL-3,4-DIHYDROQUINOLIN-2(1H)-ONE

Q16539 — Mitogen-activated protein kinase 14

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Attributes

UniProt ID
Q16539
Protein Name
Mitogen-activated protein kinase 14
Ligand Name
1-(2,6-DICHLOROPHENYL)-5-(2,4-DIFLUOROPHENYL)-7-PIPERIDIN-4-YL-3,4-DIHYDROQUINOLIN-2(1H)-ONE
DrugBank ID
DB01948
PDB Ligand Accession
358
ChEMBL ID
CHEMBL564912
PubChem ID
447725
InChIKey
VXIYTVJEIXMAQF-UHFFFAOYSA-N
SMILES
c1cc(c(c(c1)Cl)N2c3cc(cc(c3CCC2=O)c4ccc(cc4F)F)C5CCNCC5)Cl
Drug Action
n/a
Affinity Metrics
ic50:0.74 nM