DrugDomain logoDrugDomain

1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA

Q16539 — Mitogen-activated protein kinase 14

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Attributes

UniProt ID
Q16539
Protein Name
Mitogen-activated protein kinase 14
Ligand Name
1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA
DrugBank ID
DB03044
PDB Ligand Accession
B96
ChEMBL ID
CHEMBL103667
PubChem ID
156422
InChIKey
MVCOAUNKQVWQHZ-UHFFFAOYSA-N
SMILES
Cc1ccc(cc1)n2c(cc(n2)C(C)(C)C)NC(=O)Nc3ccc(c4c3cccc4)OCCN5CCOCC5
Drug Action
n/a
Affinity Metrics
ki:0.1 nM
ic50:0.1 nM
kd:0.098 nM
kon:84900 nM
koff:0.000008 nM