4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE
Q16539 — Mitogen-activated protein kinase 14
Attributes
UniProt ID
Protein Name
Mitogen-activated protein kinase 14
Ligand Name
4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE
DrugBank ID
PDB Ligand Accession
ChEMBL ID
PubChem ID
InChIKey
MLDQJTXFUGDVEO-UHFFFAOYSA-N
SMILES
CNC(=O)c1cc(ccn1)Oc2ccc(cc2)NC(=O)Nc3ccc(c(c3)C(F)(F)F)Cl
Drug Action
no_target_action
Affinity Metrics
ic50:37 nM
kd:260 nM