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1-(5-TERT-BUTYL-2-METHYL-2H-PYRAZOL-3-YL)-3-(4-CHLORO-PHENYL)-UREA

Q16539 — Mitogen-activated protein kinase 14

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Attributes

UniProt ID
Q16539
Protein Name
Mitogen-activated protein kinase 14
Ligand Name
1-(5-TERT-BUTYL-2-METHYL-2H-PYRAZOL-3-YL)-3-(4-CHLORO-PHENYL)-UREA
DrugBank ID
DB02277
PDB Ligand Accession
BMU
ChEMBL ID
CHEMBL87277
PubChem ID
446816
InChIKey
FWIJKWMXNHRSRO-UHFFFAOYSA-N
SMILES
CC(C)(C)c1cc(n(n1)C)NC(=O)Nc2ccc(cc2)Cl
Drug Action
n/a
Affinity Metrics
ic50:794 nM
kd:1160 nM
kon:118000 nM
koff:0.14 nM