3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamide

Q16539 — Mitogen-activated protein kinase 14

Attributes

UniProt ID

Protein Name

Mitogen-activated protein kinase 14

Ligand Name

3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamide

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

KCAJXIDMCNPGHZ-UHFFFAOYSA-N

SMILES

Cc1ccc(cc1N2C(=CC(=C(C2=O)Br)OCc3ccc(cc3F)F)C)C(=O)NC

Drug Action

n/a

Affinity Metrics

ki:2.9 nM

ic50:1.1 nM

kd:2.5 nM