3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA

Q16539 — Mitogen-activated protein kinase 14

Attributes

UniProt ID

Protein Name

Mitogen-activated protein kinase 14

Ligand Name

3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

ZWYFTKPEHRQCCW-HNNXBMFYSA-N

SMILES

CC(C(C)(C)O)Nc1nccc(n1)N(c2ccc(cc2)OC)C(=O)Nc3ccccc3Cl

Drug Action

n/a

Affinity Metrics

ic50:92 nM