DrugDomain logoDrugDomain

2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE

Q16539 — Mitogen-activated protein kinase 14

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Attributes

UniProt ID
Q16539
Protein Name
Mitogen-activated protein kinase 14
Ligand Name
2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE
DrugBank ID
DB08395
PDB Ligand Accession
PGJ
ChEMBL ID
CHEMBL371491
PubChem ID
4369443
InChIKey
ZSOXFJURLPCSOO-UHFFFAOYSA-N
SMILES
CCOCN1C(=C(C(=O)O1)c2ccc(cc2)F)c3ccnc(n3)Oc4ccccc4O
Drug Action
n/a
Affinity Metrics
ic50:460 nM