DrugDomain logoDrugDomain

[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE

Q16539 — Mitogen-activated protein kinase 14

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Attributes

UniProt ID
Q16539
Protein Name
Mitogen-activated protein kinase 14
Ligand Name
[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE
DrugBank ID
DB08424
PDB Ligand Accession
PQB
ChEMBL ID
CHEMBL203567
PubChem ID
5327067
InChIKey
IJDQETGUEUJVTB-HNNXBMFYSA-N
SMILES
c1cc(cc(c1)OCC(CO)O)C(=O)c2cnn(c2N)c3ccc(cc3)F
Drug Action
inhibitor
Affinity Metrics
ic50:180 nM