(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

Q8N6T7 — NAD-dependent protein deacylase sirtuin-6

Attributes

UniProt ID

Protein Name

NAD-dependent protein deacylase sirtuin-6

Ligand Name

(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

DrugBank ID

PDB Ligand Accession

ChEMBL ID

PubChem ID

InChIKey

FJLGEFLZQAZZCD-MCBHFWOFSA-N

SMILES

CC(C)n1c2ccccc2c(c1C=CC(CC(CC(=O)O)O)O)c3ccc(cc3)F

Drug Action

no_target_action

Affinity Metrics

ec50:7100 nM