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2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide

Q99835 — Protein smoothened

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Attributes

UniProt ID
Q99835
Protein Name
Protein smoothened
Ligand Name
2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide
DrugBank ID
DB08828
PDB Ligand Accession
VIS
ChEMBL ID
CHEMBL473417
PubChem ID
24776445
InChIKey
BPQMGSKTAYIVFO-UHFFFAOYSA-N
SMILES
CS(=O)(=O)c1ccc(c(c1)Cl)C(=O)Nc2ccc(c(c2)c3ccccn3)Cl
Drug Action
antagonist
Affinity Metrics
ki:16.2 nM
ic50:0.4 nM
kd:97.5 nM
ec50:2 nM