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7-ethyl-10-hydroxycamptothecin

Q9UNQ0 — Broad substrate specificity ATP-binding cassette transporter ABCG2

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Attributes

UniProt ID
Q9UNQ0
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Ligand Name
7-ethyl-10-hydroxycamptothecin
DrugBank ID
DB05482
PDB Ligand Accession
RS4
ChEMBL ID
CHEMBL837
PubChem ID
104842
InChIKey
FJHBVJOVLFPMQE-QFIPXVFZSA-N
SMILES
CCc1c2cc(ccc2nc3c1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)O
Drug Action
no_target_action
Affinity Metrics
ic50:176 nM