Ligand name: Pralsetinib
PDB ligand accession: Q4J
DrugBank: DB15822
PubChem: n/a
ChEMBL: CHEMBL4297597
InChI Key: GBLBJPZSROAGMF-BATDWUPUSA-N
SMILES: Cc1cc(n[nH]1)Nc2cc(nc(n2)C3CCC(CC3)(C(=O)NC(C)c4ccc(nc4)n5cc(cn5)F)OC)C

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Organoheterocyclic compounds
    • Class: Pyridines and derivatives
      • Subclass: Pyrazolylpyridines

List of proteins that are targets for DB15822

#	DrugDomain Data	UniProt Accession	Protein name	Drug Action	Affinity data
1	Q16288_Q4J	Q16288	NT-3 growth factor	inhibitor
2	P11362_Q4J	P11362	Fibroblast growth factor	inhibitor
3	Q08345_Q4J	Q08345	Epithelial discoidin domain-containing	inhibitor
4	O60674_Q4J	O60674	Tyrosine-protein kinase JAK2	inhibitor
5	P04629_Q4J	P04629	High affinity nerve	inhibitor
6	P23458_Q4J	P23458	Tyrosine-protein kinase JAK1	inhibitor
7	P21802_Q4J	P21802	Fibroblast growth factor	inhibitor
8	P36888_Q4J	P36888	Receptor-type tyrosine-protein kinase	inhibitor
9	P07949_Q4J	P07949	Proto-oncogene tyrosine-protein kinase	inhibitor
10	P09619_Q4J	P09619	Platelet-derived growth factor	inhibitor
11	P35968_Q4J	P35968	Vascular endothelial growth	inhibitor