Ligand name: 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide
PDB ligand accession: 0LI
DrugBank: DB08901
PubChem: 24826799
ChEMBL: CHEMBL1171837
InChI Key: PHXJVRSECIGDHY-UHFFFAOYSA-N
SMILES: Cc1ccc(cc1C#Cc2cnc3n2nccc3)C(=O)Nc4ccc(c(c4)C(F)(F)F)CN5CCN(CC5)C

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Benzenoids
    • Class: Benzene and substituted derivatives
      • Subclass: Anilides

List of proteins that are targets for 0LI

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	P12931_0LI	P12931	inhibitor	IC50(nM) = 2.5
2	P10721_0LI	P10721	inhibitor	IC50(nM) = 1.7
3	P00519_0LI	P00519	inhibitor	IC50(nM) = 0.3 Kd(nM) = 0.7 EC50(nM) = 0.05
4	O43353_0LI	O43353	n/a	IC50(nM) = 1.0
5	P00523_0LI	P00523	n/a	IC50(nM) = 0.9 Kd(nM) = 0.7
6	P35968_0LI	P35968	inhibitor	Ki(nM) = 1.5 IC50(nM) = 1.5
7	P22607_0LI	P22607	inhibitor	IC50(nM) = 9.4
8	Q01973_0LI	Q01973	n/a
9	P07949_0LI	P07949	inhibitor	IC50(nM) = 0.3
10	Q08345_0LI	Q08345	n/a	IC50(nM) = 9.4
11	P36888_0LI	P36888	inhibitor	IC50(nM) = 0.3
12	P21802_0LI	P21802	inhibitor	IC50(nM) = 1.3
13	D3DSX2_0LI	D3DSX2	n/a
14	P11362_0LI	P11362	inhibitor	IC50(nM) = 0.7
15	P00520_0LI	P00520	n/a
16	Q02763_0LI	Q02763	inhibitor
17	P22455_0LI	P22455	inhibitor	IC50(nM) = 7.1
18	Q9NWZ3_0LI	Q9NWZ3	n/a
19	P06239_0LI	P06239	inhibitor	IC50(nM) = 0.28
20	P16234_0LI	P16234	inhibitor	IC50(nM) = 1.1
21	P07948_0LI	P07948	inhibitor	IC50(nM) = 0.16
22	P15056_0LI	P15056	n/a
23	P11274_0LI	P11274	inhibitor