Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: CYTIDINE-5'-TRIPHOSPHATE
PDB ligand accession: CTP
DrugBank: DB02431
PubChem: 6176
ChEMBL: CHEMBL223533
InChI Key: PCDQPRRSZKQHHS-XVFCMESISA-N
SMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

ClassyFire chemical classification:

List of proteins that are targets for CTP

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 P04050_CTP P04050 DNA-directed RNA polymerase n/a
2 Q06755_CTP Q06755 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase n/a
3 F9UST1_CTP F9UST1 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide n/a
4 O66914_CTP O66914 3-deoxy-manno-octulosonate cytidylyltransferase (EC n/a
5 A7RNF3_CTP A7RNF3 S-adenosylmethionine-dependent nucleotide dehydratase n/a
6 Q9NP87_CTP Q9NP87 DNA-directed DNA/RNA polymerase n/a
7 E5RPG3_CTP E5RPG3 Genome polyprotein [Cleaved n/a
8 Q9HUM0_CTP Q9HUM0 RNA-binding protein Hfq n/a
9 Q5UQL3_CTP Q5UQL3 Nucleoside diphosphate kinase n/a
10 Q9HJA6_CTP Q9HJA6 Riboflavin kinase (RFK) n/a
11 P00478_CTP P00478 Aspartate carbamoyltransferase regulatory n/a
12 R5MX27_CTP R5MX27 deleted n/a
13 P21951_CTP P21951 DNA polymerase epsilon n/a
14 P77965_CTP P77965 DNA-directed RNA polymerase n/a
15 P0DTD1_CTP P0DTD1 Replicase polyprotein 1ab n/a
16 A5U2S7_CTP A5U2S7 ATP-dependent dethiobiotin synthetase n/a
17 D0EZK6_CTP D0EZK6 RNA-directed RNA polymerase n/a
18 Q97W02_CTP Q97W02 DNA polymerase IV n/a
19 P26396_CTP P26396 Glucose-1-phosphate cytidylyltransferase (EC n/a
20 Q980Q4_CTP Q980Q4 Uracil phosphoribosyltransferase (EC n/a
21 Q9X1B3_CTP Q9X1B3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase n/a
22 Q91H74_CTP Q91H74 Genome polyprotein n/a
23 Q7SIB1_CTP Q7SIB1 CCA-adding enzyme (EC n/a
24 B7MLA1_CTP B7MLA1 CTP synthase (EC n/a
25 Q13394_CTP Q13394 Putative nucleotidyltransferase MAB21L1 n/a
26 P0A776_CTP P0A776 RNA pyrophosphohydrolase (EC n/a
27 Q8RQE8_CTP Q8RQE8 DNA-directed RNA polymerase n/a
28 Q2G1C0_CTP Q2G1C0 Ribitol-5-phosphate cytidylyltransferase 1 n/a
29 P17812_CTP P17812 CTP synthase 1 n/a
30 Q8RQE9_CTP Q8RQE9 DNA-directed RNA polymerase n/a
31 P0A7F3_CTP P0A7F3 Aspartate carbamoyltransferase regulatory n/a
32 Q9WZH4_CTP Q9WZH4 tRNA nucleotidyl transferase-related n/a
33 P74766_CTP P74766 Aspartate carbamoyltransferase regulatory n/a
34 Q70ET3_CTP Q70ET3 Genome polyprotein n/a
35 A0A1C7DQ98_CTP A0A1C7DQ98 CCA-adding protein n/a
36 P03300_CTP P03300 Genome polyprotein [Cleaved n/a
37 P28274_CTP P28274 CTP synthase 1 n/a
38 Q9YF05_CTP Q9YF05 CDP-archaeol synthase (EC n/a
39 O66728_CTP O66728 A-adding tRNA nucleotidyltransferase n/a
40 O06961_CTP O06961 Propionate kinase (EC n/a
41 P27623_CTP P27623 Glycerol-3-phosphate cytidylyltransferase (GCT) n/a
42 F1NBW0_CTP F1NBW0 Mitochondrial poly(A) polymerase n/a
43 P0A8V4_CTP P0A8V4 DNA-directed RNA polymerase n/a
44 P06746_CTP P06746 DNA polymerase beta n/a
45 O28126_CTP O28126 CCA-adding enzyme (EC n/a
46 Q1D3H3_CTP Q1D3H3 ParBC domain-containing protein n/a
47 O27473_CTP O27473 Single-stranded-DNA-specific exonuclease RecJ n/a
48 O74339_CTP O74339 Phosphatidate cytidylyltransferase, mitochondrial n/a
49 B8GW30_CTP B8GW30 Chromosome-partitioning protein ParB n/a
50 Q9Y253_CTP Q9Y253 DNA polymerase eta n/a
51 P96864_CTP P96864 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase n/a
52 P11041_CTP P11041 Polyhedrin (C-polyhedrin) n/a
53 Q66EC2_CTP Q66EC2 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n/a
54 P12689_CTP P12689 DNA repair protein n/a
55 Q9NRF8_CTP Q9NRF8 CTP synthase 2 n/a
56 A0A7I9CFN1_CTP A0A7I9CFN1 deleted n/a
57 P42216_CTP P42216 3-deoxy-manno-octulosonate cytidylyltransferase (EC n/a
58 A0R560_CTP A0R560 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase n/a
59 Q5KWC1_CTP Q5KWC1 DNA polymerase I n/a
60 P0A7E5_CTP P0A7E5 CTP synthase (EC n/a
61 A0A6A5PYW3_CTP A0A6A5PYW3 deleted n/a
62 Q99447_CTP Q99447 Ethanolamine-phosphate cytidylyltransferase (EC n/a
63 A0QWT2_CTP A0QWT2 Coenzyme A biosynthesis n/a
64 P08518_CTP P08518 DNA-directed RNA polymerase n/a
65 E8Y329_CTP E8Y329 deleted n/a
66 P0A0Z8_CTP P0A0Z8 N-acylneuraminate cytidylyltransferase (EC n/a
67 O05338_CTP O05338 DNA primase (EC n/a
68 Q63T71_CTP Q63T71 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase n/a
69 P0ABQ0_CTP P0ABQ0 Coenzyme A biosynthesis n/a
70 R6BY16_CTP R6BY16 deleted n/a
71 P56689_CTP P56689 DNA polymerase (EC n/a
72 Q46893_CTP Q46893 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase n/a
73 Q5V8Y6_CTP Q5V8Y6 RNA-directed RNA polymerase n/a
74 D9J2T9_CTP D9J2T9 rRNA N-glycosylase (EC n/a
75 P0A8V2_CTP P0A8V2 DNA-directed RNA polymerase n/a
76 P13569_CTP P13569 Cystic fibrosis transmembrane n/a
77 Q9CXY6_CTP Q9CXY6 Interleukin enhancer-binding factor n/a
78 Q9BZX2_CTP Q9BZX2 Uridine-cytidine kinase 2 n/a
79 Q9WYL6_CTP Q9WYL6 Uncharacterized protein n/a
80 Q8CBB9_CTP Q8CBB9 S-adenosylmethionine-dependent nucleotide dehydratase n/a
81 P00582_CTP P00582 DNA polymerase I n/a
82 P04951_CTP P04951 3-deoxy-manno-octulosonate cytidylyltransferase (EC n/a
83 O43173_CTP O43173 Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3 n/a
84 Q2SWT6_CTP Q2SWT6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase n/a
85 Q38087_CTP Q38087 DNA-directed DNA polymerase n/a
86 E5RPG2_CTP E5RPG2 Genome polyprotein [Cleaved n/a
87 A3DJ38_CTP A3DJ38 Metallophosphoesterase n/a
88 Q6NYR1_CTP Q6NYR1 P2X purinoceptor 4a n/a
89 Q9VUL1_CTP Q9VUL1 CTP synthase (EC n/a
90 O13833_CTP O13833 Terminal uridylyltransferase cid1 n/a
91 P0A8T7_CTP P0A8T7 DNA-directed RNA polymerase n/a
92 O67911_CTP O67911 CC-adding tRNA nucleotidyltransferase n/a
93 O10693_CTP O10693 Polyhedrin n/a
94 Q381M1_CTP Q381M1 Terminal uridylyltransferase 4 n/a
95 P9WPQ5_CTP P9WPQ5 Dethiobiotin synthetase BioD n/a
96 A0A1Q9N9I8_CTP A0A1Q9N9I8 deleted n/a