Ligand name: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE
PDB ligand accession: TTC
DrugBank: DB01030
PubChem: 60700
ChEMBL: CHEMBL84
InChI Key: UCFGDBYHRUNTLO-QHCPKHFHSA-N
SMILES: CCC1(C2=C(COC1=O)C(=O)N3Cc4cc5c(ccc(c5CN(C)C)O)nc4C3=C2)O

ClassyFire chemical classification:

• Kingdom: Organic compounds
  • Superclass: Alkaloids and derivatives
    • Class: Camptothecins
      • Subclass: None

List of proteins that are targets for TTC

#	DrugDomain Data	UniProt Accession	Drug Action	Affinity data
1	Q9UNQ0_TTC	Q9UNQ0	n/a
2	P11387_TTC	P11387	inhibitor	IC50(nM) = 21.0 Kd(nM) = 26.5 EC50(nM) = 54.0
3	O15439_TTC	O15439	n/a
4	Q969P6_TTC	Q969P6	inhibitor