Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: URIDINE-5'-DIPHOSPHATE-GLUCOSE
PDB ligand accession: UPG
DrugBank: DB01861
PubChem: 8629
ChEMBL: CHEMBL375951
InChI Key: HSCJRCZFDFQWRP-JZMIEXBBSA-N
SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OC3C(C(C(C(O3)CO)O)O)O)O)O

ClassyFire chemical classification:

List of proteins that are targets for UPG

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 A3N2T3_UPG A3N2T3 UDP-glucose:protein N-beta-glucosyltransferase (UDP-Glc:protein n/a
2 Q13304_UPG Q13304 Uracil nucleotide/cysteinyl leukotriene regulator
3 P27115_UPG P27115 Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC n/a
4 Q92410_UPG Q92410 Alpha,alpha-trehalose-phosphate synthase [UDP-forming] n/a
5 A0A0K1H2R6_UPG A0A0K1H2R6 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) n/a
6 Q73WU1_UPG Q73WU1 Glucosyl-3-phosphoglycerate synthase (GpgS) n/a
7 P04397_UPG P04397 Bifunctional protein GAL10 n/a
8 Q9F7G8_UPG Q9F7G8 Glucose-1-phosphate thymidylyltransferase (EC n/a
9 K5B7Z4_UPG K5B7Z4 Glucosyl-3-phosphoglycerate synthase (EC n/a
10 Q9QUI0_UPG Q9QUI0 Transforming protein RhoA n/a
11 P00740_UPG P00740 Coagulation factor IX n/a
12 A0A0M4KE44_UPG A0A0M4KE44 UDP-glycosyltransferase 13 (MiUGT13) n/a
13 O25363_UPG O25363 UTP--glucose-1-phosphate uridylyltransferase (EC n/a
14 Q5IFH7_UPG Q5IFH7 Glycosyltransferase (EC 2.4.1.-) n/a
15 P14769_UPG P14769 N-acetyllactosaminide alpha-1,3-galactosyltransferase (EC n/a
16 Q9F7K6_UPG Q9F7K6 Glucose-1-phosphate thymidylyltransferase (EC n/a
17 A0A385Z7H9_UPG A0A385Z7H9 Glycosyltransferase (EC 2.4.1.-) n/a
18 Q89399_UPG Q89399 UDP-Glucose glycosyltransferase n/a
19 Q9BRQ3_UPG Q9BRQ3 Uridine diphosphate glucose n/a
20 P04519_UPG P04519 DNA alpha-glucosyltransferase (AGT) n/a
21 X2KZJ9_UPG X2KZJ9 UTP--glucose-1-phosphate uridylyltransferase (EC n/a
22 Q3JPI3_UPG Q3JPI3 UDP-glucose 4-epimerase (EC n/a
23 A0A003_UPG A0A003 MoeE5 n/a
24 E8MF10_UPG E8MF10 UDP-glucose 4-epimerase (EC n/a
25 Q9HUF6_UPG Q9HUF6 UDP-glucose:(Heptosyl) LPS alpha n/a
26 A0A6I8WFN2_UPG A0A6I8WFN2 GgCGT n/a
27 Q9M9P3_UPG Q9M9P3 UTP--glucose-1-phosphate uridylyltransferase 2 n/a
28 Q3HTL6_UPG Q3HTL6 Oleandomycin glycosyltransferase n/a
29 G0SB58_UPG G0SB58 UDP-glucose-glycoprotein glucosyltransferase-like protein n/a
30 A0A0A1HA03_UPG A0A0A1HA03 UDP-glycosyltransferase 708C1 (EC n/a
31 P33038_UPG P33038 UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC n/a
32 Q9AGY4_UPG Q9AGY4 Glucose-1-phosphate thymidylyltransferase (EC n/a
33 Q6M6R3_UPG Q6M6R3 deleted n/a
34 Q189K5_UPG Q189K5 Toxin A (EC n/a
35 A5U1Q6_UPG A5U1Q6 Glucosyl-3-phosphoglycerate synthase (EC n/a
36 Q5WWY0_UPG Q5WWY0 Glucosyltransferase Lgt1 n/a
37 Q48485_UPG Q48485 UDP-galactopyranose mutase (UGM) n/a
38 C0HI30_UPG C0HI30 UDP-glucose 4-epimerase (EC n/a
39 O58762_UPG O58762 Trehalose synthase (EC n/a
40 P08037_UPG P08037 Beta-1,4-galactosyltransferase 1 (Beta-1,4-GalTase n/a
41 D3G6S4_UPG D3G6S4 UTP-monosaccharide-1-phosphate uridylyltransferase (EC n/a
42 P9WMW9_UPG P9WMW9 Glucosyl-3-phosphoglycerate synthase (GpgS) n/a
43 O25511_UPG O25511 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) n/a
44 K7NBW3_UPG K7NBW3 Mogroside I-E synthase n/a
45 P09148_UPG P09148 Galactose-1-phosphate uridylyltransferase (Gal-1-P n/a
46 A0A2R2JFJ4_UPG A0A2R2JFJ4 Glycosyltransferase (EC 2.4.1.-) n/a
47 T1KUK4_UPG T1KUK4 UDP-glycosyltransferase 202A2 n/a
48 Q06321_UPG Q06321 Sterol 3-beta-glucosyltransferase (EC n/a
49 P13280_UPG P13280 Glycogenin-1 (GN-1) (GN1) n/a
50 P16154_UPG P16154 Toxin A (EC n/a
51 P9WN67_UPG P9WN67 UDP-glucose 4-epimerase (EC n/a
52 A0A246CDW5_UPG A0A246CDW5 deleted n/a
53 Q388T4_UPG Q388T4 UTP--glucose-1-phosphate uridylyltransferase (EC n/a
54 A0A2D0TCJ6_UPG A0A2D0TCJ6 UGGT n/a
55 A0A045H759_UPG A0A045H759 NAD-dependent epimerase/dehydratase (EC n/a
56 Q46342_UPG Q46342 Cytotoxin-L (EC 3.4.22.-) n/a
57 C8VAU8_UPG C8VAU8 UDP-glucose 4-epimerase (EC n/a
58 P16442_UPG P16442 Histo-blood group ABO n/a
59 Q0P8H3_UPG Q0P8H3 UDP-glucose 6-dehydrogenase (UDP-Glc n/a
60 O48917_UPG O48917 UDP-sulfoquinovose synthase, chloroplastic n/a
61 F2L613_UPG F2L613 Trehalose phosphorylase/synthase n/a
62 P31677_UPG P31677 Trehalose-6-phosphate synthase (TPS) n/a
63 A4JT02_UPG A4JT02 UTP--glucose-1-phosphate uridylyltransferase (EC n/a
64 Q7Z4J2_UPG Q7Z4J2 Putative glycosyltransferase 6 n/a
65 Q8KN66_UPG Q8KN66 UDP-N-acetyl-alpha-D-glucosaminouronate 4-epimerase (UDP-GlcNAcA n/a
66 Q3U4G3_UPG Q3U4G3 Xyloside xylosyltransferase 1 n/a
67 Q9WYX9_UPG Q9WYX9 UDP-glucose 4-epimerase, putative n/a
68 Q16851_UPG Q16851 UTP--glucose-1-phosphate uridylyltransferase (EC n/a
69 A1RUM9_UPG A1RUM9 UDP-glucose 6-dehydrogenase (EC n/a
70 A0A482AQV3_UPG A0A482AQV3 Glycosyltransferase (EC 2.4.1.-) n/a
71 P46976_UPG P46976 Glycogenin-1 (GN-1) (GN1) n/a
72 Q8YQW3_UPG Q8YQW3 Alr3699 protein n/a
73 P04547_UPG P04547 DNA beta-glucosyltransferase (BGT) n/a
74 Q4QDU3_UPG Q4QDU3 UTP--glucose-1-phosphate uridylyltransferase (EC n/a
75 Q14376_UPG Q14376 UDP-glucose 4-epimerase (EC n/a
76 P09147_UPG P09147 UDP-glucose 4-epimerase (EC n/a
77 O60701_UPG O60701 UDP-glucose 6-dehydrogenase (UDP-Glc n/a