DB00246
Proteins interacting with this molecule.
| DrugDomain Data | DrugBank | PDB Ligand | UniProt | Protein Name | Drug Action | Affinity |
|---|---|---|---|---|---|---|
| Explore | DB00246 | XEF | P08172 | Muscarinic acetylcholine receptor M2 | antagonist | Ki 2440 nM |
| Explore | DB00246 | XEF | P08173 | Muscarinic acetylcholine receptor M4 | antagonist | Ki 1600 nM |
| Explore | DB00246 | XEF | P08908 | 5-hydroxytryptamine receptor 1A | agonist | Ki 1.6 nM |
| Explore | DB00246 | XEF | P08912 | Muscarinic acetylcholine receptor M5 | antagonist | Ki 1600 nM |
| Explore | DB00246 | XEF | P08913 | Alpha-2A adrenergic receptor | antagonist | Ki 154 nM |
| Explore | DB00246 | XEF | P11229 | Muscarinic acetylcholine receptor M1 | antagonist | Ki 300 nM |
| Explore | DB00246 | XEF | P14416 | D dopamine receptor | antagonist | Ki 0.8 nM | IC50 5 nM |
| Explore | DB00246 | XEF | P18089 | Alpha-2B adrenergic receptor | antagonist | Ki 48 nM |
| Explore | DB00246 | XEF | P18825 | Alpha-2C adrenergic receptor | antagonist | Ki 59 nM |
| Explore | DB00246 | XEF | P20309 | Muscarinic acetylcholine receptor M3 | antagonist | Ki 1300 nM |
| Explore | DB00246 | XEF | P21728 | D dopamine receptor | antagonist | Ki 9.5 nM |
| Explore | DB00246 | XEF | P21917 | D dopamine receptor dopamine receptor | antagonist | Ki 0.8 nM |
| Explore | DB00246 | XEF | P21918 | D dopamine receptor dopamine receptor | antagonist | n/a |
| Explore | DB00246 | XEF | P28221 | 5-hydroxytryptamine receptor 1D | antagonist | Ki 2.4 nM |
| Explore | DB00246 | XEF | P28222 | 5-hydroxytryptamine receptor 1B | antagonist | Ki 0.99 nM |
| Explore | DB00246 | XEF | P28223 | 5-hydroxytryptamine receptor 2A | antagonist | Ki 0.08 nM | IC50 0.42 nM |
| Explore | DB00246 | XEF | P28335 | 5-hydroxytryptamine receptor 2C | antagonist | Ki 0.55 nM |
| Explore | DB00246 | XEF | P28566 | 5-hydroxytryptamine receptor 1E | antagonist | Ki 360 nM |
| Explore | DB00246 | XEF | P34969 | 5-hydroxytryptamine receptor 7 | antagonist | Ki 5 nM |
| Explore | DB00246 | XEF | P35348 | Alpha-1A adrenergic receptor | antagonist | Ki 2.6 nM | IC50 11 nM |
Showing 20 of 25 interactions