DB00619
Proteins interacting with this molecule.
| DrugDomain Data | DrugBank | PDB Ligand | UniProt | Protein Name | Drug Action | Affinity |
|---|---|---|---|---|---|---|
| Explore | DB00619 | STI | P00519 | Tyrosine-protein kinase ABL1 | inhibitor | Ki 13 nM | IC50 1.1 nM | Kd 1 nM | EC50 34 nM |
| Explore | DB00619 | STI | P00520 | Tyrosine-protein kinase ABL1 | no_target_action | IC50 10.8 nM |
| Explore | DB00619 | STI | P00523 | Proto-oncogene tyrosine-protein kinase Src | no_target_action | IC50 2784 nM |
| Explore | DB00619 | STI | P04629 | High affinity nerve growth factor receptor | antagonist | Kd 10000 nM |
| Explore | DB00619 | STI | P06239 | Tyrosine-protein kinase Lck | no_target_action | Ki 6893 nM | IC50 160 nM | Kd 40 nM |
| Explore | DB00619 | STI | P07333 | Macrophage colony-stimulating factor 1 receptor | antagonist | IC50 291 nM | Kd 10 nM |
| Explore | DB00619 | STI | P09619 | Platelet-derived growth factor receptor beta | antagonist | Ki 3 nM | IC50 50 nM | Kd 14 nM |
| Explore | DB00619 | STI | P10721 | Mast/stem cell growth factor receptor Kit | antagonist | Ki 14 nM | IC50 16 nM | Kd 3 nM | EC50 100 nM |
| Explore | DB00619 | STI | P11274 | Breakpoint cluster region protein | inhibitor | n/a |
| Explore | DB00619 | STI | P16083 | Ribosyldihydronicotinamide dehydrogenase | no_target_action | Ki 39 nM | IC50 43 nM |
| Explore | DB00619 | STI | P16234 | Platelet-derived growth factor receptor alpha | antagonist | Ki 2 nM | IC50 2 nM | Kd 31 nM | EC50 90 nM |
| Explore | DB00619 | STI | P27707 | Deoxycytidine kinase | no_target_action | n/a |
| Explore | DB00619 | STI | P37231 | Peroxisome proliferator-activated receptor gamma | no_target_action | n/a |
| Explore | DB00619 | STI | P42684 | Tyrosine-protein kinase ABL2 | no_target_action | IC50 272 nM | Kd 10 nM |
| Explore | DB00619 | STI | P43405 | Tyrosine-protein kinase SYK | no_target_action | Ki 5000 nM | IC50 5000 nM | Kd 10000 nM |
| Explore | DB00619 | STI | Q08345 | Epithelial discoidin domain-containing receptor 1 | antagonist | IC50 43 nM | Kd 0.7 nM |
| Explore | DB00619 | STI | Q16539 | Mitogen-activated protein kinase 14 | no_target_action | IC50 13700 nM | Kd 3162 nM |
| Explore | DB00619 | STI | Q16832 | Discoidin domain-containing receptor 2 | antagonist | IC50 141 nM | Kd 15 nM |
| Explore | DB00619 | STI | Q59FK4 | Tyrosine-protein kinase | no_target_action | n/a |
| Explore | DB00619 | STI | Q9UNQ0 | Broad substrate specificity ATP-binding cassette transporter ABCG2 | no_target_action | IC50 500 nM |
Showing 20 of 20 interactions