Gene name: RIPK2
Protein name: Receptor-interacting serine/threonine-protein kinase
List of molecules and drugs that interact with protein O43353
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | O43353_0LI | 0LI | DB08901 | 24826799 | CHEMBL1171837 | 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide | n/a | IC50(nM) = 1.0 |
| 2 | O43353_6GD | 6GD | n/a | 67469084 | CHEMBL3823499 | 6-(tert-butylsulfonyl)-N-(5-fluoro-2H-indazol-3-yl)quinolin-4-amine | n/a | |
| 3 | O43353_6GE | 6GE | n/a | 9927432 | CHEMBL237347 | 4-methyl-3-{[6-(methylsulfonyl)quinolin-4-yl]amino}phenol | n/a | |
| 4 | O43353_9WS | 9WS | n/a | 46175112 | CHEMBL1078785 | N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine-3-carboxamide | n/a | |
| 5 | O43353_9XA | 9XA | n/a | 137348872 | CHEMBL4162788 | 4-{6-(tert-butylsulfonyl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridin-3-yl}-6-chloropyridin-2-amine | n/a | |
| 6 | O43353_ACP | ACP | DB03909 | 91532 | CHEMBL133463 | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | n/a | |
| 7 | O43353_BW8 | BW8 | n/a | 132275098 | CHEMBL4206212 | 2-[2-fluoranyl-4-[[2-fluoranyl-4-[2-(methylcarbamoyl)pyridin-4-yl]oxy-phenyl]carbamoylamino]phenyl]sulfanylethanoic acid | n/a | |
| 8 | O43353_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 9 | O43353_CO | CO | n/a | 104729 | n/a | COBALT (II) ION | n/a | |
| 10 | O43353_E7N | E7N | n/a | 133053558 | CHEMBL4786742 | ~{N}-[5-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-2-methoxy-phenyl]propane-1-sulfonamide | n/a | |
| 11 | O43353_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 12 | O43353_GEZ | GEZ | n/a | 60194465 | CHEMBL4293287 | 6-~{tert}-butylsulfonyl-~{N}-(3,4-dimethyl-1~{H}-pyrazol-5-yl)-7-methoxy-quinolin-4-amine | n/a | |
| 13 | O43353_IQ7 | IQ7 | n/a | 53475688 | CHEMBL3628628 | 2-(2-(4-CHLOROPHENYL)-1H-IMIDAZOL-5-YL)-N,1-BIS(2-METHOXYETHYL)-1H-BENZO[D]IMIDAZOLE-5-CARBOXAMIDE | n/a | |
| 14 | O43353_K9T | K9T | n/a | 73386708 | CHEMBL4596287 | 2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethyl dihydrogen phosphate | n/a | |
| 15 | O43353_KA2 | KA2 | n/a | 71258526 | CHEMBL4514780 | 2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethanol | n/a | |
| 16 | O43353_KRE | KRE | n/a | 135348339 | CHEMBL4784430 | ~{N}-[3-[2-azanyl-5-(4-piperazin-1-ylphenyl)pyridin-3-yl]-5-methoxy-phenyl]methanesulfonamide | n/a | |
| 17 | O43353_M2B | M2B | n/a | 1802 | CHEMBL4544218 | 5-Amino-1-Phenylpyrazole-4-Carboxamide | n/a | |
| 18 | O43353_M5W | M5W | n/a | 145704691 | CHEMBL4440460 | 5-amino-1-~{tert}-butyl-3-(3-methoxyphenyl)pyrazole-4-carboxamide | n/a | |
| 19 | O43353_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 20 | O43353_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 21 | O43353_Q9J | Q9J | n/a | 145704714 | CHEMBL4527824 | (5S,6S,8R)-2-(1,3-benzothiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8-methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide | n/a | |
| 22 | O43353_SB2 | SB2 | DB08521 | 9543416 | n/a | 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE | n/a | |
| 23 | O43353_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 24 | O43353_XYW | XYW | n/a | 91971264 | CHEMBL3628627 | 2,6-bis(fluoranyl)-N-[3-[5-[2-[(3-methylsulfonylphenyl)amino]pyrimidin-4-yl]-2-morpholin-4-yl-1,3-thiazol-4-yl]phenyl]benzenesulfonamide | n/a | |
| 25 | O43353_SR8 | SR8 | n/a | 9819877 | CHEMBL166031 | 1-(5-TERT-BUTYL-1,2-OXAZOL-3-YL)-3-(4-PYRIDIN-4-YLOXYPHENYL)UREA | n/a | |
| 26 | O43353_STU | STU | DB02010 | 44259 | CHEMBL388978 | STAUROSPORINE | n/a | |
| 27 | O43353_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |