Gene name: EGFR
Protein name: Epidermal growth factor
List of molecules and drugs that interact with protein P00533
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P00533_03P | 03P | n/a | 11620908 | CHEMBL1614725 | N-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide | n/a | |
| 2 | P00533_0UN | 0UN | n/a | 44607530 | CHEMBL1229592 | N-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide | n/a | |
| 3 | P00533_0WM | 0WM | DB08916 | 10184653 | CHEMBL1173655 | (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide | inhibitor | IC50(nM) = 0.01 Kd(nM) = 0.1 EC50(nM) = 7.5 |
| 4 | P00533_0WN | 0WN | n/a | 60147041 | n/a | N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide | n/a | |
| 5 | P00533_1C9 | 1C9 | DB11963 | 11511120 | CHEMBL2110732 | (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}-4-(piperidin-1-yl)but-2-enamide | inhibitor | |
| 6 | P00533_1E8 | 1E8 | DB09053 | 24821094 | CHEMBL1873475 | 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one | n/a | IC50(nM) = 0.5 Kd(nM) = 3.9 EC50(nM) = 49.0 |
| 7 | P00533_1WY | 1WY | n/a | 78225366 | n/a | N-(3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamide | n/a | |
| 8 | P00533_2PE | 2PE | n/a | 4867 | n/a | NONAETHYLENE GLYCOL | n/a | |
| 9 | P00533_35Z | 35Z | n/a | 156621361 | CHEMBL5083976 | 2-[2-(3-methoxyphenyl)pyrimidin-4-yl]-1'-prop-2-enoyl-spiro[5,6-dihydro-1~{H}-pyrrolo[3,2-c]pyridine-7,4'-piperidine]-4-one | n/a | |
| 10 | P00533_3LH | 3LH | n/a | 137348155 | n/a | N-{2-methyl-5-[2-oxo-9-(1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-1(2H)-yl]phenyl}propanamide | n/a | |
| 11 | P00533_3QS | 3QS | n/a | 86278565 | CHEMBL3354189 | 1-cyclopentyl-N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-1H-pyrrolo[3,2-c]pyridin-6-amine | n/a | |
| 12 | P00533_3QW | 3QW | n/a | 86278566 | CHEMBL3354187 | N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-1-(propan-2-yl)-2-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine | n/a | |
| 13 | P00533_3QY | 3QY | n/a | 86278567 | CHEMBL3354186 | N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-2-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine | n/a | |
| 14 | P00533_3R0 | 3R0 | n/a | 86278568 | CHEMBL3354185 | N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-2-(1H-pyrazol-4-yl)-3H-imidazo[4,5-c]pyridin-6-amine | n/a | |
| 15 | P00533_3R1 | 3R1 | n/a | 68672618 | CHEMBL3354183 | 2,6-dichloro-N-{2-[(2-{[(2S)-1-hydroxypropan-2-yl]amino}-6-methylpyrimidin-4-yl)amino]pyridin-4-yl}benzamide | n/a | |
| 16 | P00533_4YV | 4YV | n/a | 90178371 | CHEMBL3734825 | 1-cyclopentyl-N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-1H-imidazo[4,5-c]pyridin-6-amine | n/a | |
| 17 | P00533_4YW | 4YW | n/a | 91971390 | CHEMBL3735045 | 2-methyl-N-{2-[4-(methylsulfonyl)piperidin-1-yl]pyrimidin-4-yl}-1-(propan-2-yl)-1H-imidazo[4,5-c]pyridin-6-amine | n/a | |
| 18 | P00533_4YX | 4YX | n/a | 90183483 | CHEMBL3736430 | N-{2-[4-(2-aminoethyl)-4-methoxypiperidin-1-yl]pyrimidin-4-yl}-2-methyl-1-(propan-2-yl)-1H-imidazo[4,5-c]pyridin-6-amine | n/a | |
| 19 | P00533_4Z8 | 4Z8 | n/a | 76280903 | CHEMBL3735689 | 2,2-dimethyl-3-[(4-{[2-methyl-1-(propan-2-yl)-1H-imidazo[4,5-c]pyridin-6-yl]amino}pyrimidin-2-yl)amino]propanamide | n/a | |
| 20 | P00533_4ZB | 4ZB | n/a | 91971391 | n/a | (3R)-3-methyl-1-(4-{[2-methyl-1-(propan-2-yl)-1H-imidazo[4,5-c]pyridin-6-yl]amino}pyrimidin-2-yl)pyrrolidine-3-carboxamide | n/a | |
| 21 | P00533_4ZG | 4ZG | n/a | 90183696 | CHEMBL3735782 | N~2~-[2-methyl-2-(methylsulfonyl)propyl]-N~4~-[2-methyl-1-(propan-2-yl)-1H-imidazo[4,5-c]pyridin-6-yl]pyrimidine-2,4-diamine | n/a | |
| 22 | P00533_4ZH | 4ZH | n/a | 91971392 | CHEMBL3736210 | 2-methyl-N-[2-(2-methyl-2-methylsulfonyl-propoxy)pyrimidin-4-yl]-1-propan-2-yl-imidazo[4,5-c]pyridin-6-amine | n/a | |
| 23 | P00533_4ZJ | 4ZJ | n/a | 90183560 | CHEMBL3736183 | N-[2-[(3R,4S)-3-fluoranyl-4-methoxy-piperidin-1-yl]pyrimidin-4-yl]-2-methyl-1-propan-2-yl-imidazo[4,5-c]pyridin-6-amine | n/a | |
| 24 | P00533_4ZQ | 4ZQ | n/a | 90183462 | n/a | (1R)-1-{6-({2-[(3R,4S)-3-fluoro-4-methoxypiperidin-1-yl]pyrimidin-4-yl}amino)-1-[(2S)-1,1,1-trifluoropropan-2-yl]-1H-imidazo[4,5-c]pyridin-2-yl}ethanol | n/a | |
| 25 | P00533_4ZR | 4ZR | n/a | 90183423 | n/a | (1R)-1-{6-({2-[(3S,4R)-3-fluoro-4-methoxypiperidin-1-yl]pyrimidin-4-yl}amino)-1-[(2S)-1,1,1-trifluoropropan-2-yl]-1H-imidazo[4,5-c]pyridin-2-yl}ethanol | n/a | |
| 26 | P00533_57N | 57N | n/a | 51607467 | n/a | (2R)-2-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)-2-phenyl-N-(1,3-thiazol-2-yl)acetamide | n/a | |
| 27 | P00533_5N3 | 5N3 | n/a | 92132732 | CHEMBL3758602 | ~{N}-(7-chloranyl-1~{H}-indazol-3-yl)-7,7-dimethyl-2-(1~{H}-pyrazol-4-yl)-5~{H}-furo[3,4-d]pyrimidin-4-amine | n/a | |
| 28 | P00533_5N4 | 5N4 | n/a | 92132733 | CHEMBL3759096 | ~{N}-(1~{H}-indazol-3-yl)-7,7-dimethyl-2-(2-methylpyrazol-3-yl)-5~{H}-furo[3,4-d]pyrimidin-4-amine | n/a | |
| 29 | P00533_5Q2 | 5Q2 | n/a | 102515536 | CHEMBL3780553 | 4-[2-(4-chlorophenyl)ethylamino]-~{N}-[4-(4-methylpiperazin-1-yl)phenyl]-2-oxidanylidene-1~{H}-pyridine-3-carboxamide | n/a | |
| 30 | P00533_5Q3 | 5Q3 | n/a | 102515537 | CHEMBL3781993 | 4-[(2-azanylpyrimidin-4-yl)amino]-~{N}-[4-(4-methylpiperazin-1-yl)phenyl]-2-oxidanylidene-1~{H}-pyridine-3-carboxamide | n/a | |
| 31 | P00533_5Q4 | 5Q4 | n/a | 102515538 | CHEMBL3780090 | 4-[(2-methoxyphenyl)amino]-~{N}-[4-(4-methylpiperazin-1-yl)phenyl]-2-oxidanylidene-1~{H}-pyridine-3-carboxamide | n/a | |
| 32 | P00533_5X4 | 5X4 | n/a | 137348410 | n/a | ~{N}-[7-methyl-1-[(3~{R})-1-propanoylazepan-3-yl]benzimidazol-2-yl]-3-(trifluoromethyl)benzamide | n/a | |
| 33 | P00533_5XH | 5XH | n/a | 72703989 | CHEMBL3960167 | ~{N}-[1-[(3~{R})-1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl]-7-methyl-benzimidazol-2-yl]-2-methyl-pyridine-4-carboxamide | n/a | |
| 34 | P00533_60B | 60B | n/a | 90183442 | CHEMBL5281373 | ~{N}-[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]-2-methyl-1-propan-2-yl-imidazo[4,5-c]pyridin-6-amine | n/a | |
| 35 | P00533_60D | 60D | n/a | 118668055 | CHEMBL5279275 | 6-[[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]amino]-~{N}-(oxan-4-yl)-1-propan-2-yl-pyrrolo[3,2-c]pyridine-3-carboxamide | n/a | |
| 36 | P00533_60E | 60E | n/a | 121595975 | CHEMBL5282118 | 2-[1-[1-[(2~{S})-butan-2-yl]-6-[[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]amino]pyrazolo[4,3-c]pyridin-3-yl]azetidin-3-yl]propan-2-ol | n/a | |
| 37 | P00533_630 | 630 | n/a | 135036586 | n/a | 1-{(3R,4R)-3-[({5-chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}propan-1-one | n/a | |
| 38 | P00533_633 | 633 | n/a | 137348422 | n/a | N-{3-[(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl}propanamide | n/a | |
| 39 | P00533_634 | 634 | n/a | 137348423 | n/a | N-[3-({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]propanamide | n/a | |
| 40 | P00533_63A | 63A | n/a | 137348424 | n/a | 1-[(3R,4R)-3-[({2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-(trifluoromethyl)pyrr olidin-1-yl]propan-1-one | n/a | |
| 41 | P00533_63M | 63M | n/a | 58063383 | n/a | N-tert-butyl-5-{[(1-methyl-1H-pyrazol-5-yl)sulfonyl]amino}pyrazolo[1,5-a]pyrimidine-3-carboxamide | n/a | |
| 42 | P00533_63N | 63N | n/a | 76284458 | n/a | N-{2-[1-(cyclopropylsulfonyl)-1H-pyrazol-4-yl]pyrimidin-4-yl}-1-(propan-2-yl)-1H-imidazo[4,5-c]pyridin-6-amine | n/a | |
| 43 | P00533_6GY | 6GY | DB12267 | 68165256 | CHEMBL3545311 | 5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine | inhibitor | |
| 44 | P00533_6HJ | 6HJ | n/a | 137348469 | CHEMBL4094959 | (R)-1-(3-(4-amino-3-(1-methyl-1H-indol-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one | n/a | |
| 45 | P00533_6HL | 6HL | n/a | 137348470 | CHEMBL4095447 | (R)-1-(3-(4-amino-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one | n/a | |
| 46 | P00533_6JS | 6JS | n/a | 121487955 | n/a | 3-(furan-2-yl)-N-[5-(furan-2-yl)-2-methoxyphenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine | n/a | |
| 47 | P00533_7G9 | 7G9 | n/a | 126653761 | n/a | ~{N}-[3-[[5-fluoranyl-2-[[4-(2-methoxyethoxy)phenyl]amino]pyrimidin-4-yl]amino]phenyl]propanamide | n/a | |
| 48 | P00533_7VH | 7VH | n/a | 151183629 | CHEMBL5176897 | 5-chloranyl-N-[5-chloranyl-2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-(1-ethylsulfonylindol-3-yl)pyrimidin-2-amine | n/a | |
| 49 | P00533_7XO | 7XO | n/a | 54759842 | CHEMBL2178351 | N2-[4-(4-methylpiperazin-1-yl)phenyl]-N8-phenyl-9-propan-2-yl-purine-2,8-diamine | n/a | |
| 50 | P00533_7XR | 7XR | n/a | 54760383 | CHEMBL2178352 | 9-cyclopentyl-N2-[4-(4-methylpiperazin-1-yl)phenyl]-N8-phenyl-purine-2,8-diamine | n/a | |
| 51 | P00533_7XU | 7XU | n/a | 54761307 | CHEMBL2178353 | 9-cyclohexyl-N2-[4-(4-methylpiperazin-1-yl)phenyl]-N8-phenyl-purine-2,8-diamine | n/a | |
| 52 | P00533_80U | 80U | n/a | 130203720 | CHEMBL4060187 | 1-[(3R)-3-[4-azanyl-3-[3-chloranyl-4-[(1-methylimidazol-2-yl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one | n/a | |
| 53 | P00533_816 | 816 | n/a | 130203496 | n/a | 1-[(3R)-3-[4-azanyl-3-[3-chloranyl-4-[(6-methylpyridin-2-yl)methoxy]phenyl]pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one | n/a | |
| 54 | P00533_81C | 81C | n/a | 129281618 | n/a | N-[5-[[5-chloranyl-4-[(2-propan-2-ylsulfonylphenyl)amino]pyrimidin-2-yl]amino]-2-(4-ethylpiperazin-1-yl)-4-methoxy-phenyl]prop-2-enamide | n/a | |
| 55 | P00533_85X | 85X | DB17029 | 3501 | CHEMBL302449 | 12-(2-Cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole | n/a | |
| 56 | P00533_8AM | 8AM | n/a | 137348695 | n/a | N-[(3R,4R)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-(propan-2-yl)-9H-purin-2-yl}pyrrolidin-3-yl]propanamide | n/a | |
| 57 | P00533_8BM | 8BM | n/a | 124222449 | CHEMBL4206604 | 4-(4-{[2-{[(3S)-1-acetylpyrrolidin-3-yl]amino}-9-(propan-2-yl)-9H-purin-6-yl]amino}phenyl)-1-methylpiperazin-1-ium | n/a | |
| 58 | P00533_8BP | 8BP | n/a | 137348699 | n/a | N-[(3R,4R)-4-fluoro-1-{6-[(1-methyl-1H-pyrazol-4-yl)amino]-9-(propan-2-yl)-9H-purin-2-yl}pyrrolidin-3-yl]propanamide | n/a | |
| 59 | P00533_8BS | 8BS | n/a | 137348700 | n/a | N-[(3R,4R)-4-fluoro-1-{6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl}pyrrolidin-3-yl]propanamide | n/a | |
| 60 | P00533_8JC | 8JC | DB11907 | 57335384 | CHEMBL3545308 | N-[3-[[2-[[4-(4-ethanoylpiperazin-1-yl)-2-methoxy-phenyl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide | modulator | |
| 61 | P00533_8LU | 8LU | n/a | 137348724 | n/a | (2R)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]-1-(2-fluoranylethanoyl)pyrrolidine-2-carboxamide | n/a | |
| 62 | P00533_8OV | 8OV | n/a | 137348735 | n/a | N-(3-{[2-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)propanamide | n/a | |
| 63 | P00533_8RC | 8RC | DB12036 | 71667668 | CHEMBL3663929 | 6-ethyl-3-[[4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-5-[(3R)-1-prop-2-enoylpyrrolidin-3-yl]oxy-pyrazin e-2-carboxamide | inhibitor | |
| 64 | P00533_9JO | 9JO | n/a | n/a | CHEMBL4294743 | N-{trans-4-[3-(2-chlorophenyl)-7-{[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino}-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl]cyclohexyl}propanamide | n/a | |
| 65 | P00533_9LL | 9LL | n/a | 125461985 | CHEMBL4452106 | (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide | n/a | |
| 66 | P00533_ADP | ADP | DB16833 | 6022 | CHEMBL14830 | ADENOSINE-5'-DIPHOSPHATE | n/a | |
| 67 | P00533_AEE | AEE | DB12558 | 10297043 | CHEMBL587723 | 6-{4-[(4-ETHYLPIPERAZIN-1-YL)METHYL]PHENYL}-N-[(1R)-1-PHENYLETHYL]-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE | n/a | |
| 68 | P00533_AMP | AMP | DB00131 | 6083 | CHEMBL752 | ADENOSINE MONOPHOSPHATE | n/a | |
| 69 | P00533_ANP | ANP | n/a | 33113 | CHEMBL1230989 | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | n/a | |
| 70 | P00533_AQ4 | AQ4 | DB00530 | 176870 | CHEMBL553 | [6,7-BIS(2-METHOXY-ETHOXY)QUINAZOLINE-4-YL]-(3-ETHYNYLPHENYL)AMINE | antagonist | Ki(nM) = 0.1 IC50(nM) = 0.029 Kd(nM) = 0.35 |
| 71 | P00533_BMA | BMA | n/a | 439680 | n/a | beta-D-mannopyranose | n/a | |
| 72 | P00533_C6O | C6O | n/a | 137436802 | n/a | 6-(2-chloranyl-3-fluoranyl-phenyl)-5-methyl-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[(3S)-1-propanoylpiperidin-3-yl]pyrido[2,3-d]pyrimidin-7-one | n/a | |
| 73 | P00533_CD | CD | n/a | 31193 | n/a | CADMIUM ION | n/a | |
| 74 | P00533_CIT | CIT | DB04272 | 311;19782904;88113319; | CHEMBL1261 | CITRIC ACID | n/a | |
| 75 | P00533_CKO | CKO | n/a | 46212971 | CHEMBL4521381 | E-4-(dimethylamino)-N-[3-[4-[[(1S)-2-oxidanyl-1-phenyl-ethyl]amino]-6-phenyl-furo[2,3-d]pyrimidin-5-yl]phenyl]but-2-enamide | n/a | |
| 76 | P00533_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 77 | P00533_DJK | DJK | DB07662 | 4708 | CHEMBL285063 | N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE | inhibitor | IC50(nM) = 0.08 |
| 78 | P00533_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 79 | P00533_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 80 | P00533_EUX | EUX | n/a | 154701097 | n/a | N-[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]-7-(4-methylpiperazin-1-yl)-5-propan-2-yl-9-[2,2,2-tris(fluoranyl)ethoxy]pyrido[4,3-b]indol-3-amine | n/a | |
| 81 | P00533_F62 | F62 | n/a | 72201501 | CHEMBL3633143 | N-[3-[2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-5-methyl-7-oxidanylidene-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide | n/a | |
| 82 | P00533_FI3 | FI3 | n/a | 132265779 | n/a | N-[4-({[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino}methyl)phenyl]propanamide | n/a | |
| 83 | P00533_FLC | FLC | n/a | 31348 | n/a | CITRATE ANION | n/a | |
| 84 | P00533_FMM | FMM | DB01259 | 208908 | CHEMBL554 | N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE | antagonist | Ki(nM) = 3.0 IC50(nM) = 0.06 Kd(nM) = 0.92 |
| 85 | P00533_FZP | FZP | n/a | 137349380 | n/a | (4-fluorophenyl)methyl {2-[(1-methyl-1H-pyrazol-3-yl)amino]pyrimidin-4-yl}[3-(propanoylamino)phenyl]carbamate | n/a | |
| 86 | P00533_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 87 | P00533_HKI | HKI | n/a | 44560357 | n/a | N-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)butanamide | n/a | |
| 88 | P00533_HYZ | HYZ | n/a | 24880017 | n/a | N-[1-(3-fluorobenzyl)-1H-indazol-5-yl]-5-[(piperidin-1-ylamino)methyl]pyrimidine-4,6-diamine | n/a | |
| 89 | P00533_I0A | I0A | n/a | 163359802 | CHEMBL5205581 | 25-chloro-11-(ethylsulfonyl)-44-morpholino-11H-5,12-dioxa-3-aza-1(3,6)-indola-2(4,2)-pyrimidina-4(1,3)-benzenacyclododecaphane | n/a | |
| 90 | P00533_IOD | IOD | n/a | 30165 | n/a | IODIDE ION | n/a | |
| 91 | P00533_IRE | IRE | DB00317 | 123631 | CHEMBL939 | Gefitinib | antagonist | Ki(nM) = 0.4 IC50(nM) = 0.1 Kd(nM) = 0.52 EC50(nM) = 2162.0 |
| 92 | P00533_ITI | ITI | n/a | 46886319 | CHEMBL1090356 | N-[3-(5-{2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl}imidazo[2,1-b][1,3]thiazol-6-yl)phenyl]-2-phenylacetamide | n/a | |
| 93 | P00533_ITQ | ITQ | n/a | 15942671 | n/a | 1,2,3,4-Tetrahydrogen Staurosporine | n/a | |
| 94 | P00533_JAU | JAU | n/a | 163184841 | CHEMBL5076986 | 5-chloranyl-N2-[3-chloranyl-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-N4-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine | n/a | |
| 95 | P00533_JBJ | JBJ | n/a | 124173751 | n/a | (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-{1-oxo-6-[4-(piperazin-1-yl)phenyl]-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide | n/a | |
| 96 | P00533_KJ8 | KJ8 | n/a | 71571535 | CHEMBL2347963 | N-[3-(4-{[(1S)-2-hydroxy-1-phenylethyl]amino}-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl]-N~3~,N~3~-dimethyl-beta-alaninamide | n/a | |
| 97 | P00533_KJQ | KJQ | n/a | 46855200 | CHEMBL1172781 | (2S)-2-[(5,6-diphenylfuro[2,3-d]pyrimidin-4-yl)amino]-2-phenylethanol | n/a | |
| 98 | P00533_KJR | KJR | n/a | 59322682 | CHEMBL2347965 | N-[3-(4-{[(1S)-2-hydroxy-1-phenylethyl]amino}-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl]acetamide | n/a | |
| 99 | P00533_KJV | KJV | n/a | 71571536 | CHEMBL2347960 | 4-(dimethylamino)-N-[3-(4-{[(1S)-2-hydroxy-1-phenylethyl]amino}-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl]butanamide | n/a | |
| 100 | P00533_KXY | KXY | n/a | 165412415 | n/a | (2R)-2-[4-[bis(fluoranyl)methyl]-6-[2-[4-[[4-(hydroxymethyl)piperidin-1-yl]methyl]phenyl]ethynyl]-7-methyl-indazol-2-yl]-2-spiro[6,7-dihydropyrrolo[1,2-c]imidazole-5,1'-cyclopropane]-1-yl-N-(1,3-thiazol-2-yl)ethanamide | n/a | |
| 101 | P00533_KY9 | KY9 | n/a | 165412416 | n/a | (2R)-2-(6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-1-yl)-2-[5-[2-[4-[[4-(hydroxymethyl)piperidin-1-yl]methyl]phenyl]ethynyl]-3-oxidanylidene-7-(trifluoromethyl)-1H-isoindol-2-yl]-N-(1,3-thiazol-2-yl)ethanamide | n/a | |
| 102 | P00533_L0N | L0N | n/a | 139210951 | CHEMBL5220529 | ~{N}-[3-[6-[4-(4-methylpiperazin-1-yl)phenyl]-4-(2-methylpropoxy)-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide | n/a | |
| 103 | P00533_L0Q | L0Q | n/a | 139210950 | CHEMBL5220645 | ~{N}-[3-[6-[4-(4-methylpiperazin-1-yl)phenyl]-4-propan-2-yloxy-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide | n/a | |
| 104 | P00533_L1H | L1H | n/a | 139593668 | CHEMBL4591327 | 3-fluoranyl-~{N}-[1-(2-methyl-2-oxidanyl-propyl)benzimidazol-2-yl]-5-pyridin-3-yl-benzamide | n/a | |
| 105 | P00533_L1K | L1K | n/a | 139593669 | CHEMBL4434788 | ~{N}-[1-(2-methyl-2-oxidanyl-propyl)benzimidazol-2-yl]-2-phenyl-pyridine-4-carboxamide | n/a | |
| 106 | P00533_L3Z | L3Z | n/a | 139593670 | CHEMBL4519157 | 8-oxa-14,21,23,28-tetraazapentacyclo[23.3.1.02,7.014,22.015,20]nonacosa-1(28),2(7),3,5,15,17,19,21,25(29),26-decaen-24-one | n/a | |
| 107 | P00533_M0R | M0R | n/a | 165430654 | CHEMBL5206110 | 19-chloro-22-methoxy-8,9,11,12,14,15-hexahydro-21H-4,6-ethenopyrimido[5,4-m][1,4,7,10,15]benzotetraoxazacycloheptadecine | n/a | |
| 108 | P00533_M19 | M19 | n/a | 165430655 | CHEMBL5206697 | 4-(5-chloro-4-fluoro-2-hydroxyanilino)-7-methoxyquinazolin-6-ol | n/a | |
| 109 | P00533_M1O | M1O | n/a | 165430656 | CHEMBL5180914 | 19-chloro-18-fluoro-22-methoxy-8,9,11,12,14,15-hexahydro-21H-4,6-ethenopyrimido[5,4-m][1,4,7,10,15]benzotetraoxazacycloheptadecine | n/a | |
| 110 | P00533_MAN | MAN | n/a | 185698 | CHEMBL365590 | alpha-D-mannopyranose | n/a | |
| 111 | P00533_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 112 | P00533_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 113 | P00533_N78 | N78 | n/a | 154700553 | n/a | ~{N}-[5-[4-[[4-[[1,3-bis(oxidanylidene)isoindol-2-yl]methyl]phenyl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethyloxy)phenyl]propanamide | n/a | |
| 114 | P00533_N7B | N7B | n/a | 154700554 | n/a | ~{N}-[2-(2-hydroxyethyloxy)-5-[4-[[1-(phenylmethyl)indazol-5-yl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide | n/a | |
| 115 | P00533_N7K | N7K | n/a | 154700555 | n/a | ~{N}-[3-[4-[[1-(phenylmethyl)indazol-5-yl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide | n/a | |
| 116 | P00533_N7Q | N7Q | n/a | 154700556 | n/a | ~{N}-[5-[4-[[3-chloranyl-4-(pyridin-2-ylmethoxy)phenyl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethyloxy)phenyl]propanamide | n/a | |
| 117 | P00533_N7W | N7W | n/a | 154700557 | n/a | ~{N}-[5-[4-[[3-chloranyl-4-(pyridin-2-ylmethoxy)phenyl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]-2-[2-(dimethylamino)ethoxy]phenyl]propanamide | n/a | |
| 118 | P00533_N7Z | N7Z | n/a | 154700558 | n/a | ~{N}-[5-[4-[[3-chloranyl-4-(pyridin-2-ylmethoxy)phenyl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(3-oxidanylpropoxy)phenyl]propanamide | n/a | |
| 119 | P00533_N82 | N82 | n/a | 154700559 | n/a | ~{N}-[5-[4-[[4-[[1,3-bis(oxidanylidene)isoindol-2-yl]methyl]phenyl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]-2-[2-(dimethylamino)ethoxy]phenyl]propanamide | n/a | |
| 120 | P00533_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 121 | P00533_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 122 | P00533_NO3 | NO3 | DB14049 | 943 | CHEMBL186200 | NITRATE ION | n/a | |
| 123 | P00533_NQ1 | NQ1 | n/a | 145946092 | CHEMBL4520903 | 10-benzyl-8-fluoro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one | n/a | |
| 124 | P00533_NSO | NSO | n/a | 168264808 | CHEMBL5404639 | ~{N}-[3-[[6-fluoranyl-2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]quinazolin-4-yl]amino]phenyl]prop-2-enamide | n/a | |
| 125 | P00533_O44 | O44 | n/a | 126956694 | CHEMBL4855850 | 4-[(4-{4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]-6-[(prop-2-yn-1-yl)carbamoyl]pyrimidin-2-yl}piperazin-1-yl)methyl]benzene-1-sulfonyl fluoride | n/a | |
| 126 | P00533_O57 | O57 | n/a | 145946101 | CHEMBL5180830 | 10-benzyl-2-fluoro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one | n/a | |
| 127 | P00533_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 128 | P00533_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 129 | P00533_POX | POX | n/a | 17747343 | CHEMBL255237 | 4-amino-6-{[1-(3-fluorobenzyl)-1H-indazol-5-yl]amino}pyrimidine-5-carbaldehyde O-(2-methoxyethyl)oxime | n/a | |
| 130 | P00533_PT | PT | n/a | 105166 | n/a | PLATINUM (II) ION | n/a | |
| 131 | P00533_Q6K | Q6K | n/a | 71244256 | n/a | ~{N}-[2-[2-(dimethylamino)ethyl-methyl-amino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]propanamide | n/a | |
| 132 | P00533_QCR | QCR | n/a | 164575524 | n/a | (3S,4R)-3-fluoro-1-(4-{[4-(methylamino)-1-(propan-2-yl)pyrido[3,4-d]pyridazin-7-yl]amino}pyrimidin-2-yl)piperidin-4-ol | n/a | |
| 133 | P00533_QFO | QFO | n/a | 156550550 | CHEMBL5173517 | (3S,4R)-3-fluoro-1-(4-{[8-{3-[(methanesulfonyl)methyl]azetidin-1-yl}-5-(propan-2-yl)-2,7-naphthyridin-3-yl]amino}pyrimidin-2-yl)-3-methylpiperidin-4-ol | n/a | |
| 134 | P00533_QP1 | QP1 | n/a | 146035924 | n/a | N-{3-[(4-{4-(4-fluorophenyl)-2-[(2-methoxyethyl)sulfanyl]-1H-imidazol-5-yl}pyridin-2-yl)amino]-4-methoxyphenyl}propanamide | n/a | |
| 135 | P00533_QP4 | QP4 | n/a | 146035925 | n/a | 4-[4-(4-fluorophenyl)-2-(3-methoxypropyl)-1H-imidazol-5-yl]-2-phenyl-3H-pyrrolo[2,3-b]pyridine | n/a | |
| 136 | P00533_QP7 | QP7 | n/a | 132496692 | CHEMBL4101719 | 3-[4-(4-fluorophenyl)-5-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-imidazol-2-yl]propan-1-ol | n/a | |
| 137 | P00533_QQJ | QQJ | n/a | 137654533 | CHEMBL4094927 | N-[3-({4-[4-(4-fluorophenyl)-2-(methylsulfanyl)-1H-imidazol-5-yl]pyridin-2-yl}amino)-4-methoxyphenyl]propanamide | n/a | |
| 138 | P00533_QQM | QQM | n/a | 135314117 | CHEMBL4090686 | N-[3-({4-[4-(4-fluorophenyl)-2-(3-hydroxypropyl)-1H-imidazol-5-yl]pyridin-2-yl}amino)-4-methoxyphenyl]propanamide | n/a | |
| 139 | P00533_R1W | R1W | n/a | 146411125 | n/a | ~{N}-[5-[4-chloranyl-2-[4-(4-methylpiperazin-1-yl)phenyl]-1~{H}-pyrrolo[2,3-b]pyridin-3-yl]-2-methyl-phenyl]propanamide | n/a | |
| 140 | P00533_R25 | R25 | n/a | 168008975 | CHEMBL5287229 | propan-2-yl 2-[[4-(4-azanylpiperidin-1-yl)-2-methoxy-phenyl]amino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate | n/a | |
| 141 | P00533_R28 | R28 | n/a | 162639267 | n/a | propan-2-yl 2-[[4-[2-(dimethylamino)ethyl-methyl-amino]-2-methoxy-5-(propanoylamino)phenyl]amino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate | n/a | |
| 142 | P00533_R2E | R2E | n/a | 162639268 | n/a | 1-[4-[4-[[3,4-bis(chloranyl)-2-fluoranyl-phenyl]amino]-7-methoxy-quinazolin-6-yl]oxypiperidin-1-yl]propan-1-one | n/a | |
| 143 | P00533_R85 | R85 | n/a | 155920468 | CHEMBL5086066 | 5-chloranyl-~{N}2-[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxy-5-(1-methylpyrazol-4-yl)phenyl]-~{N}4-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine | n/a | |
| 144 | P00533_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 145 | P00533_TOV | TOV | n/a | 155818892 | CHEMBL5188250 | N-(3-{5-[2-(acetylamino)pyridin-4-yl]-2-(methylsulfanyl)-1H-imidazol-4-yl}phenyl)-2-fluoro-5-hydroxybenzamide | n/a | |
| 146 | P00533_TQA | TQA | n/a | 155818893 | n/a | N-(3-{5-[2-(acetylamino)pyridin-4-yl]-2-(methylsulfanyl)-1H-imidazol-4-yl}phenyl)-2-[(1-oxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzamide | n/a | |
| 147 | P00533_UEJ | UEJ | n/a | 155908654 | CHEMBL5183286 | N-(3-{5-[2-(acetylamino)pyridin-4-yl]-2-(methylsulfanyl)-1H-imidazol-4-yl}phenyl)-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-6-fluoro-3-hydroxybenzamide | n/a | |
| 148 | P00533_V58 | V58 | n/a | 168008976 | CHEMBL5270693 | phenyl 2-[[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxy-phenyl]amino]-4-(1H-indol-3-yl)pyrimidine-5-carboxylate | n/a | |
| 149 | P00533_VNS | VNS | n/a | 156595832 | n/a | (2R)-2-(5-fluoro-2-hydroxyphenyl)-2-{6-[4-(1-methylpiperidin-4-yl)phenyl]-1-oxo-1,3-dihydro-2H-isoindol-2-yl}-N-(1,3-thiazol-2-yl)acetamide | n/a | |
| 150 | P00533_VO7 | VO7 | n/a | 71496460 | CHEMBL3353411 | N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-5-{[4-(1H-indol-3-yl)pyrimidin-2-yl]amino}-4-methoxyphenyl)propanamide | n/a | |
| 151 | P00533_W19 | W19 | n/a | 71583657 | CHEMBL2348417 | 4-{[4-(1-benzothiophen-4-yloxy)-3-chlorophenyl]amino}-N-(2-hydroxyethyl)-8,9-dihydro-7H-pyrimido[4,5-b]azepine-6-carboxamide | n/a | |
| 152 | P00533_W2P | W2P | n/a | 78225569 | n/a | N-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-4-(dimethylamino)butanamide | n/a | |
| 153 | P00533_W2R | W2R | n/a | 59453176 | CHEMBL2322330 | 1-{3-[2-chloro-4-({5-[2-(2-hydroxyethoxy)ethyl]-5H-pyrrolo[3,2-d]pyrimidin-4-yl}amino)phenoxy]phenyl}-3-cyclohexylurea | n/a | |
| 154 | P00533_W32 | W32 | n/a | 59484694 | CHEMBL2348415 | 4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-N-[2-(methylsulfonyl)ethyl]-8,9-dihydro-7H-pyrimido[4,5-b]azepine-6-carboxamide | n/a | |
| 155 | P00533_X9B | X9B | n/a | 155246509 | n/a | (2P)-3-(3-chloro-2-methoxyanilino)-2-[3-(2-methoxy-2-methylpropoxy)pyridin-4-yl]-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one | n/a | |
| 156 | P00533_X9H | X9H | DB18763 | 117918742 | CHEMBL4650281 | N-[(5P,8S,10R)-4-amino-6-methyl-5-(quinolin-3-yl)-8,9-dihydropyrimido[5,4-b]indolizin-8-yl]prop-2-enamide | n/a | |
| 157 | P00533_XA4 | XA4 | n/a | 139600318 | CHEMBL4537790 | (20R)-10,15,20-trimethyl-2-[(4-methylpiperazin-1-yl)methyl]-18,19,20,21-tetrahydro-15H,17H-12,8-(metheno)pyrazolo[3',4':2,3][1,5,10,12]oxatriazacycloheptadecino[12,11-a]benzimidazol-7(6H)-one | n/a | |
| 158 | P00533_YFA | YFA | n/a | 162625309 | n/a | (2R)-2-{5-fluoro-6-[4-(1-methylpiperidin-4-yl)phenyl]-4-oxoquinazolin-3(4H)-yl}-2-phenyl-N-(1,3-thiazol-2-yl)acetamide | n/a | |
| 159 | P00533_YUN | YUN | n/a | 4709 | CHEMBL188762 | N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}propanamide | n/a | |
| 160 | P00533_YXT | YXT | DB11787 | 11539025 | CHEMBL2364626 | ralimetinib | n/a | |
| 161 | P00533_YY3 | YY3 | DB09330 | 71496458 | CHEMBL3353410 | N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide | inhibitor | Ki(nM) = 3.5 IC50(nM) = 0.002 EC50(nM) = 6.0 |
| 162 | P00533_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 163 | P00533_ZNL | ZNL | n/a | 168719778 | n/a | N-{7-methyl-1-[(3S)-1-(prop-2-enoyl)azepan-3-yl]-1H-benzimidazol-2-yl}-5-(prop-2-enamido)thiophene-3-carboxamide | n/a | |
| 164 | P00533_ZRT | ZRT | n/a | 121269177 | n/a | N-[5-{[(4P)-4-{4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl}pyrimidin-2-yl]amino}-4-methoxy-2-(morpholin-4-yl)phenyl]propanamide | n/a | |
| 165 | P00533_LQZ | LQZ | DB00281 | 3676 | CHEMBL79 | Lidocaine | antagonist | |
| 166 | P00533_CPB | CPB | DB03496 | 5287969 | CHEMBL428690 | Alvocidib | n/a | IC50(nM) = 21000.0 Kd(nM) = 520.0 |
| 167 | P00533_ZD6 | ZD6 | DB05294 | 3081361 | CHEMBL24828 | Vandetanib | inhibitor | |
| 168 | P00533_DB05424 | n/a | DB05424 | n/a | n/a | Canertinib | inhibitor | IC50(nM) = 0.1 Kd(nM) = 0.1 |
| 169 | P00533_93J | 93J | DB05524 | 6445562 | CHEMBL607707 | Pelitinib | modulator | |
| 170 | P00533_DB05944 | n/a | DB05944 | n/a | n/a | Varlitinib | modulator | |
| 171 | P00533_DB06021 | n/a | DB06021 | n/a | n/a | AV-412 | n/a | |
| 172 | P00533_CY0 | CY0 | DB07602 | n/a | n/a | S-{3-[(4-ANILINOQUINAZOLIN-6-YL)AMINO]-3-OXOPROPYL}-L-CYSTEINE | n/a | |
| 173 | P00533_DB11737 | n/a | DB11737 | n/a | n/a | Icotinib | antagonist | |
| 174 | P00533_DB11828 | n/a | DB11828 | n/a | n/a | Neratinib | inhibitor | |
| 175 | P00533_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor | |
| 176 | P00533_DB12114 | n/a | DB12114 | n/a | n/a | Poziotinib | inhibitor | |
| 177 | P00533_DB13164 | n/a | DB13164 | n/a | n/a | Olmutinib | inhibitor | |
| 178 | P00533_DB15035 | n/a | DB15035 | n/a | n/a | Zanubrutinib | inhibitor | |
| 179 | P00533_DB15327 | n/a | DB15327 | n/a | n/a | Abivertinib | inhibitor | |
| 180 | P00533_DB16390 | n/a | DB16390 | n/a | n/a | Mobocertinib | inhibitor |