Gene name: REN
Protein name: Renin (EC 3.4.23.15)
List of molecules and drugs that interact with protein P00797
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P00797_03D | 03D | n/a | 6323478 | n/a | (2R,4S,5S)-N-[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]-2-(cyclopropylmethyl)-4,5-dihydroxy-6-phenylhexanamide | n/a | |
| 2 | P00797_0IU | 0IU | n/a | 6323285 | n/a | (2S)-2-[(2-amino-1,3-thiazol-4-yl)methyl]-N~1~-[(1S,2R,3R)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-N~4~-[2-(d imethylamino)-2-oxoethyl]-N~4~-[(1S)-1-phenylethyl]butanediamide | n/a | |
| 3 | P00797_0LR | 0LR | n/a | 70789272 | CHEMBL2322604 | (3R,4R)-3-(naphthalen-2-ylmethoxy)-4-phenylpiperidine | n/a | |
| 4 | P00797_0LS | 0LS | n/a | 11632240 | CHEMBL2365206 | N-{[(3S,4S)-4-benzylpyrrolidin-3-yl]methyl}-4-chloro-N-phenylaniline | n/a | |
| 5 | P00797_0LT | 0LT | n/a | 11518143 | CHEMBL2365004 | N-{[(3S,4S)-4-benzylpyrrolidin-3-yl]methyl}-4-methoxy-3-(3-methoxypropoxy)-N-(propan-2-yl)benzamide | n/a | |
| 6 | P00797_0LU | 0LU | n/a | 70699421 | n/a | (2S)-1-(pyrrolidin-1-yl)-3-(9H-thioxanthen-9-yl)propan-2-ol | n/a | |
| 7 | P00797_0LW | 0LW | n/a | 70699422 | n/a | (2R)-1-(pyrrolidin-1-yl)-3-(9H-thioxanthen-9-yl)propan-2-ol | n/a | |
| 8 | P00797_0M2 | 0M2 | n/a | 78225872 | n/a | (2R)-1-(3,8-dihydrodibenzo[b,f]pyrrolo[3,4-d]azepin-2(1H)-yl)propan-2-ol | n/a | |
| 9 | P00797_0M3 | 0M3 | n/a | 11993712 | CHEMBL2322204 | (3S,5R)-N-(2,2-diphenylethyl)-5-{[(4-methylphenyl)sulfonyl]amino}piperidine-3-carboxamide | n/a | |
| 10 | P00797_0ME | 0ME | n/a | 70699423 | n/a | (3S)-N-(9H-xanthen-9-ylmethyl)piperidine-3-carboxamide | n/a | |
| 11 | P00797_0MJ | 0MJ | n/a | 11949623 | CHEMBL2322208 | (3S,5R)-5-{[(4-methylphenyl)sulfonyl]amino}-N-(9H-xanthen-9-ylmethyl)piperidine-3-carboxamide | n/a | |
| 12 | P00797_0N0 | 0N0 | n/a | 11963435 | CHEMBL2322207 | (3S,5R)-N-{[9-(4-methoxybutyl)-9H-xanthen-9-yl]methyl}-5-{[(4-methylphenyl)sulfonyl]amino}piperidine-3-carboxamide | n/a | |
| 13 | P00797_0QB | 0QB | n/a | 6323286 | n/a | (2S)-2-[(2-amino-1,3-thiazol-4-yl)methyl]-N~1~-{(1S,2S)-1-(cyclohexylmethyl)-2-hydroxy-2-[(3R)-1,5,5-trimethyl-2-oxopyrrolidin-3-yl]ethyl}-N~4~-[2-(dimethylamino)-2-oxoethyl]-N~4~-[(1S)-1-phenylethyl]butanediamide | n/a | |
| 14 | P00797_1IG | 1IG | DB06899 | 6914625 | n/a | N-{2-[6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2,2-DIMETHYL-3-OXO-2,3-DIHYDRO-4H-1,4-BENZOTHIAZIN-4-YL]ETHYL}ACETAMIDE | n/a | |
| 15 | P00797_1PE | 1PE | n/a | 62551 | CHEMBL1229766 | PENTAETHYLENE GLYCOL | n/a | |
| 16 | P00797_22X | 22X | n/a | 44543660 | CHEMBL589399 | (3R)-3-[(1S)-4-(acetylamino)-1-(3-chlorophenyl)-1-hydroxybutyl]-N-{(1S)-2-cyclohexyl-1-[(methylamino)methyl]ethyl}piperidine-1-carboxamide | n/a | |
| 17 | P00797_2IG | 2IG | DB06967 | 6914626 | n/a | 6-ETHYL-5-[9-(3-METHOXYPROPYL)-9H-CARBAZOL-2-YL]PYRIMIDINE-2,4-DIAMINE | n/a | IC50(nM) = 173.0 |
| 18 | P00797_2XF | 2XF | n/a | 78350457 | CHEMBL3318932 | tert-butyl {(3S,5R)-5-[cyclopropyl(2,3-dichlorobenzyl)carbamoyl]piperidin-3-yl}carbamate | n/a | |
| 19 | P00797_2Y9 | 2Y9 | n/a | 25143506 | CHEMBL3318957 | (3S,4R,5R)-N-cyclopropyl-N'-[(2R)-1-ethoxy-4-methylpentan-2-yl]-4-hydroxy-N-[5-(propan-2-yl)pyridin-2-yl]piperidine-3,5-dicarboxamide | n/a | |
| 20 | P00797_3IG | 3IG | DB07059 | 6914627 | CHEMBL240355 | N-{2-[6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2,2-DIMETHYL-3-OXO-2,3-DIHYDRO-4H-1,4-BENZOXAZIN-4-YL]ETHYL}ACETAMIDE | n/a | IC50(nM) = 20.0 |
| 21 | P00797_3LG | 3LG | n/a | 6914634 | n/a | (5-{[(2R)-1-(4-{3-[(2-METHOXYBENZYL)OXY]PROPOXY}PHENYL)-6-OXOPIPERAZIN-2-YL]METHOXY}-1H-INDOL-1-YL)ACETIC ACID | n/a | |
| 22 | P00797_3OW | 3OW | n/a | 49795064 | n/a | (2S,4S)-4-hydroxy-2-(1-methylethyl)-4-[(4S,13S)-18-[methyl(methylsulfonyl)amino]-2,15-dioxo-4-phenyl-11-oxa-3,14-diazatricyclo[14.3.1.1~5,9~]henicosa-1(20),5(21),6,8,16,18-hexaen-13-yl]-N-(2-methylpropyl)butanamide | n/a | |
| 23 | P00797_3OX | 3OX | n/a | 49795063 | n/a | (2S,4S)-4-hydroxy-2-(1-methylethyl)-4-[(4R,13S)-18-[methyl(methylsulfonyl)amino]-2,15-dioxo-4-phenyl-11-oxa-3,14-diazatricyclo[14.3.1.1~5,9~]henicosa-1(20),5(21),6,8,16,18-hexaen-13-yl]-N-(2-methylpropyl)butanamide | n/a | |
| 24 | P00797_3ZJ | 3ZJ | n/a | 59272004 | CHEMBL3401541 | N-({(3S,4S)-4-[(benzylsulfonyl)amino]pyrrolidin-3-yl}methyl)-4-methoxy-3-(3-methoxypropoxy)-N-(propan-2-yl)benzamide | n/a | |
| 25 | P00797_3ZK | 3ZK | n/a | 91664005 | CHEMBL3400460 | 4-methoxy-3-(3-methoxypropoxy)-N-{[(3S,4S)-4-{[(4-methylphenyl)sulfonyl]amino}pyrrolidin-3-yl]methyl}-N-(propan-2-yl)benzamide | n/a | |
| 26 | P00797_3ZN | 3ZN | n/a | 59271992 | CHEMBL3403995 | (3S,4S)-4-({[4-methoxy-3-(3-methoxypropoxy)benzoyl](propan-2-yl)amino}methyl)pyrrolidin-3-yl benzylcarbamate | n/a | |
| 27 | P00797_43T | 43T | n/a | 60149247 | CHEMBL3401350 | 3-{[(4S)-2-amino-4-methyl-6-oxo-4-(propan-2-yl)-5,6-dihydropyrimidin-1(4H)-yl]methyl}-5-fluoro-N-[(1S)-1-phenylethyl]benzamide | n/a | |
| 28 | P00797_4IG | 4IG | DB07113 | 20843156 | n/a | (2S)-6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2-(3,5-DIFLUOROPHENYL)-4-(3-METHOXYPROPYL)-2H-1,4-BENZOXAZIN-3(4H)-ONE | n/a | |
| 29 | P00797_4LG | 4LG | n/a | 6914635 | n/a | METHYL (6-{[(2R)-1-(4-{3-[(2-METHOXYBENZYL)OXY]PROPOXY}PHENYL)-6-OXOPIPERAZIN-2-YL]METHOXY}-1H-INDOL-1-YL)ACETATE | n/a | |
| 30 | P00797_5IG | 5IG | DB07174 | 6914629 | CHEMBL400431 | 6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-4-(3-METHOXYPROPYL)-2,2-DIMETHYL-2H-1,4-BENZOXAZIN-3(4H)-ONE | n/a | IC50(nM) = 90.0 |
| 31 | P00797_6IG | 6IG | n/a | 6914632 | n/a | 6-ETHYL-5-[1-(3-METHOXYPROPYL)-1,2,3,4-TETRAHYDROQUINOLIN-7-YL]-N~4~-(2-PHENYLETHYL)PYRIMIDINE-2,4-DIAMINE | n/a | |
| 32 | P00797_6VR | 6VR | n/a | 59625584 | CHEMBL3961799 | 2-~{tert}-butyl-4-(furan-2-ylmethylamino)-~{N}-(2-methylpropyl)-~{N}-[(3~{S})-piperidin-3-yl]pyrimidine-5-carboxamide | n/a | |
| 33 | P00797_6VS | 6VS | n/a | 25242438 | CHEMBL3958809 | 2-~{tert}-butyl-4-(3-methoxypropylamino)-~{N}-(2-methylpropyl)-~{N}-[(3~{S},5~{R})-5-morpholin-4-ylcarbonylpiperidin-3-yl]pyrimidine-5-carboxamide | n/a | |
| 34 | P00797_6VU | 6VU | n/a | 44554894 | CHEMBL3990145 | 1-(4-methoxybutyl)-~{N}-(2-methylpropyl)-~{N}-[(3~{S},5~{R})-5-morpholin-4-ylcarbonylpiperidin-3-yl]benzimidazole-2-carboxamide | n/a | |
| 35 | P00797_70X | 70X | n/a | 71738909 | CHEMBL3401341 | N-benzyl-3-{[(2Z,4S)-2-imino-4-methyl-6-oxo-4-(propan-2-yl)tetrahydropyrimidin-1(2H)-yl]methyl}benzamide | n/a | |
| 36 | P00797_70Y | 70Y | n/a | 71738915 | CHEMBL3401342 | (2Z,6S)-2-imino-6-methyl-3-{3-[(4R)-2-oxo-4-phenylpyrrolidin-1-yl]benzyl}-6-(propan-2-yl)tetrahydropyrimidin-4(1H)-one | n/a | |
| 37 | P00797_72X | 72X | n/a | 42615261 | CHEMBL496430 | (3R)-3-[(1S)-1-(3-chlorophenyl)-1-hydroxy-5-methoxypentyl]-N-{(1S)-2-cyclohexyl-1-[(methylamino)methyl]ethyl}piperidine-1-carboxamide | n/a | |
| 38 | P00797_74U | 74U | n/a | 719250 | CHEMBL332686 | N-[(furan-2-yl)methyl]-2-phenylquinazolin-4-amine | n/a | |
| 39 | P00797_74V | 74V | n/a | 122198474 | n/a | N-ethyl-4-{[(furan-2-yl)methyl]amino}-2-methyl-N-[(3S)-piperidin-3-yl]pyrimidine-5-carboxamide | n/a | |
| 40 | P00797_74Y | 74Y | n/a | 59625393 | CHEMBL3919906 | (azepan-1-yl)(2-{[(furan-2-yl)methyl]amino}-6-methylpyridin-3-yl)methanone | n/a | |
| 41 | P00797_74Z | 74Z | n/a | 837191 | CHEMBL3915117 | N-[(furan-2-yl)methyl]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-amine | n/a | |
| 42 | P00797_77O | 77O | n/a | 21919348 | CHEMBL3954262 | 6-chloro-N-[(furan-2-yl)methyl]pyrazin-2-amine | n/a | |
| 43 | P00797_7EJ | 7EJ | n/a | 58355693 | CHEMBL4128929 | 1-(4-methoxybutyl)-N-(2-methylpropyl)-N-[(3S,5R)-5-(morpholine-4-carbonyl)piperidin-3-yl]-5-phenyl-1H-pyrrole-2-carboxamide | n/a | |
| 44 | P00797_7EK | 7EK | n/a | 58355269 | CHEMBL4129081 | 5-(4-methoxybutyl)-N-(2-methylpropyl)-N-[(3S,5R)-5-(morpholine-4-carbonyl)piperidin-3-yl]-1-phenyl-1H-1,2,3-triazole-4-carboxamide | n/a | |
| 45 | P00797_7IG | 7IG | DB07244 | 6914633 | CHEMBL230153 | 5-{4-[(3,5-DIFLUOROBENZYL)AMINO]PHENYL}-6-ETHYLPYRIMIDINE-2,4-DIAMINE | n/a | IC50(nM) = 4000.0 |
| 46 | P00797_90D | 90D | n/a | 59620423 | n/a | methyl [(4S)-4-(3'-ethyl-6-fluoro[1,1'-biphenyl]-2-yl)-4-hydroxy-4-{(3R)-1-[4-(methylamino)butanoyl]piperidin-3-yl}butyl]carbamate | n/a | |
| 47 | P00797_9G7 | 9G7 | n/a | 24758131 | n/a | methyl [(4S)-4-(3'-ethyl-6-fluoro[1,1'-biphenyl]-2-yl)-4-hydroxy-4-{(3R)-1-[(piperidin-4-yl)acetyl]piperidin-3-yl}butyl]carbamate | n/a | |
| 48 | P00797_9JD | 9JD | n/a | 59620436 | n/a | methyl [(4S)-4-{(3R)-1-[(3S)-4-amino-3-hydroxybutanoyl]piperidin-3-yl}-4-(3'-ethyl-6-fluoro[1,1'-biphenyl]-2-yl)-4-hydroxybutyl]carbamate | n/a | |
| 49 | P00797_A5T | A5T | n/a | 16086657 | CHEMBL509903 | (1R,5S)-7-{4-[3-(2-chloro-3,6-difluorophenoxy)propyl]phenyl}-N-cyclopropyl-N-(2,3-dichlorobenzyl)-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide | n/a | |
| 50 | P00797_A6T | A6T | n/a | 42627773 | CHEMBL500811 | (1S,5R)-7-{4-[3-(2-chloro-3,6-difluorophenoxy)propyl]phenyl}-N-cyclopropyl-N-(2,3-dichlorobenzyl)-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide | n/a | |
| 51 | P00797_A7T | A7T | n/a | 11578126 | CHEMBL1230745 | (1R,5S)-N-cyclopropyl-7-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}-N-(2,3-dimethylbenzyl)-3,9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide | n/a | |
| 52 | P00797_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 53 | P00797_BFX | BFX | n/a | 10348528 | CHEMBL1088430 | 4-{4-[3-(2-bromo-5-fluorophenoxy)propyl]phenyl}-N-(2-chlorobenzyl)-N-cyclopropyl-1,2,5,6-tetrahydropyridine-3-carboxamide | n/a | |
| 54 | P00797_C39 | C39 | n/a | 9805752 | n/a | N-[(2S,4S,5S,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-7-METHYL-2-(1-METHYLETHYL)-8-OXOOCTYL]-2-(3-METHOXYPROPOXY)BENZAMIDE | n/a | |
| 55 | P00797_C40 | C40 | n/a | 10004699 | n/a | N-[(2R,4S,5S,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL]-2-(3-METHOXYPROPOXY)BENZAMIDE | n/a | |
| 56 | P00797_C41 | C41 | DB09026 | 5493444 | CHEMBL1639 | ALISKIREN | inhibitor | IC50(nM) = 0.4 |
| 57 | P00797_C47 | C47 | n/a | 24836809 | CHEMBL1231601 | METHYL (3R)-1-[(5S,6S,8R)-5-AMINO-9-BUTYLAMINO-6-HYDROXY-3,3,8-TRIMETHYL-9-OXO-NONANOYL]-3,4-DIHYDRO-2H-QUINOLINE-3-CARBOXYLATE | n/a | |
| 58 | P00797_C60 | C60 | n/a | 448382 | CHEMBL293196 | [[[3-(2-METHYL-PROPANE-2-SULFONYL)-1-BENZENYL]-2-PROPYL]-CARBONYL-HISTIDYL]-AMINO-[CYCLOHEXYLMETHYL]-[2-HYDROXY-4-ISOPROPYL]-PENTAN-5-OIC ACID BUTYLAMIDE | n/a | |
| 59 | P00797_C61 | C61 | n/a | 9982638 | CHEMBL562634 | (2R,4S,5S,7S)-5-AMINO-N-BUTYL-4-HYDROXY-7-[4-METHOXY-3-(3-METHOXYPROPOXY)BENZYL]-2,8-DIMETHYLNONANAMIDE | n/a | |
| 60 | P00797_C80 | C80 | n/a | 49866757 | n/a | (2S,4S,5R,7R)-4-AMINO-8-(BUTYLAMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXOOCTYL 1-BENZYL-1H-INDOLE-3-CARBOXYLATE | n/a | |
| 61 | P00797_CIT | CIT | DB04272 | 311;19782904;88113319; | CHEMBL1261 | CITRIC ACID | n/a | |
| 62 | P00797_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 63 | P00797_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 64 | P00797_FMT | FMT | DB01942 | 284;18971002; | CHEMBL116736 | FORMIC ACID | n/a | |
| 65 | P00797_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 66 | P00797_HHE | HHE | n/a | n/a | n/a | (2R,4S,5S)-5-amino-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-2-ethyl-4-hydroxy-N-[(1R,2S,3S,5S,7S)-5-hydroxytricyclo[3.3.1.1~3,7~]dec-2-yl]hexanamide | n/a | |
| 67 | P00797_HSQ | HSQ | n/a | 7059432 | n/a | 2-acetylamino-2-deoxy-alpha-L-idopyranose | n/a | |
| 68 | P00797_L1A | L1A | n/a | 6914630 | n/a | N-(MORPHOLIN-4-YLSULFONYL)-L-PHENYLALANYL-3-(2-AMINO-1,3-THIAZOL-4-YL)-N-{(1R,2R,3S)-1-[(1R)-CYCLOHEX-3-EN-1-YLMETHYL]-2,3-DIHYDROXY-5-METHYLHEXYL}-L-ALANINAMIDE | n/a | |
| 69 | P00797_L1B | L1B | n/a | 6914631 | n/a | 7-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-1-(3-METHOXYPROPYL)QUINOLINIUM | n/a | |
| 70 | P00797_LIX | LIX | n/a | 11963547 | CHEMBL1234021 | N-[2-({2-AMINO-6-ETHYL-5-[4-(3-METHOXYPROPYL)-2,2-DIMETHYL-3-OXO-3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-YL]PYRIMIDIN-4-YL}AMINO)ETHYL]NAPHTHALENE-2-SULFONAMIDE | n/a | |
| 71 | P00797_LIY | LIY | DB08099 | 11963546 | n/a | 6-ETHYL-5-[(2S)-1-(3-METHOXYPROPYL)-2-PHENYL-1,2,3,4-TETRAHYDROQUINOLIN-7-YL]PYRIMIDINE-2,4-DIAMINE | n/a | |
| 72 | P00797_LPN | LPN | n/a | 12001783 | CHEMBL1269671 | (3R,4S)-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropyl-4-{4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]phenyl}piperidine-3-carboxamide | n/a | |
| 73 | P00797_LPO | LPO | n/a | 46931232 | CHEMBL1234078 | (3S,4R)-N-[2-chloro-5-(2-methoxyethyl)benzyl]-N-cyclopropyl-4-{6-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]pyridin-3-yl}-4-hydroxypiperidine-3-carboxamide | n/a | |
| 74 | P00797_LPQ | LPQ | n/a | 46931234 | n/a | (3R,4S)-N-{2-chloro-5-[(cyclopropylamino)methyl]benzyl}-N-cyclopropyl-4-{6-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]pyridin-3-yl}piperidine-3-carboxamide | n/a | |
| 75 | P00797_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 76 | P00797_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 77 | P00797_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 78 | P00797_PG6 | PG6 | DB02580 | 70931 | n/a | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE | n/a | |
| 79 | P00797_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 80 | P00797_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 81 | P00797_PZ1 | PZ1 | n/a | 137349903 | n/a | (6R)-6-({[1-(3-HYDROXYPROPYL)-1,7-DIHYDROQUINOLIN-7-YL]OXY}METHYL)-1-(4-{3-[(2-METHOXYBENZYL)OXY]PROPOXY}PHENYL)PIPERAZIN-2-ONE | n/a | |
| 82 | P00797_R31 | R31 | n/a | 57519701 | n/a | (2S,4S,5S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-6-{4-[2-(3-methoxypropoxy)phenyl]-3-oxopiperazin-1-yl}-2-(propan-2-yl)hexanamide | n/a | |
| 83 | P00797_R32 | R32 | n/a | 57519702 | CHEMBL2079493 | (2S,4S,5S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-6-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-4-hydroxy-2-(propan-2-yl)hexanamide | n/a | |
| 84 | P00797_REM | REM | DB00212 | 6324659 | CHEMBL31601 | Nalpha-[(2S)-2-benzyl-3-(tert-butylsulfonyl)propanoyl]-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]-L-histidinamide | inhibitor | |
| 85 | P00797_RPF | RPF | n/a | 11840980 | CHEMBL434956 | 1-{4-[3-(2-METHOXY-BENZYLOXY)-PROPOXY]-PHENYL}-6-(1,2,,3,4-TETRAHYDRO-QUINOLIN-7-YLOXYMETHYL)-PIPERAZIN-2-ONE | n/a | |
| 86 | P00797_RX0 | RX0 | n/a | 53301844 | CHEMBL1818050 | [(1S,3R,4S)-3-amino-4-hydroxycyclopentyl]{(3R)-3-[(1S)-1-(biphenyl-2-yl)-1-hydroxy-5-methoxypentyl]piperidin-1-yl}methanone | n/a | |
| 87 | P00797_RX5 | RX5 | DB12416 | 16126898 | CHEMBL1276678 | methyl (2-{(R)-(3-chlorophenyl)[(3R)-1-({(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl}carbamoyl)piperidin-3-yl] methoxy}ethyl)carbamate | inhibitor | |
| 88 | P00797_RX6 | RX6 | n/a | 53497561 | CHEMBL2024248 | methyl (2-{(R)-(3-chlorophenyl)[(3R)-1-({(2S)-1-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propan-2-yl}carbamoyl)piperidin-3-yl]methoxy}ethyl)carbamate | n/a | |
| 89 | P00797_S51 | S51 | n/a | 46912134 | CHEMBL1235802 | 2-benzyl-1-phenyl-3-(piperazin-1-ylcarbonyl)-1H-indole | n/a | |
| 90 | P00797_S52 | S52 | n/a | 44158435 | CHEMBL1235803 | 2-phenoxy-1-phenyl-3-(piperazin-1-ylcarbonyl)-1H-indole | n/a | |
| 91 | P00797_S53 | S53 | n/a | 53346499 | CHEMBL1825187 | [7-benzyl-2-(5-fluoro-2-methylphenoxy)-1-phenyl-1H-pyrrolo[2,3-c]pyridin-3-yl](piperazin-1-yl)methanone | n/a | |
| 92 | P00797_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 93 | P00797_UA4 | UA4 | n/a | 11957418 | n/a | (2S)-6-(2,4-DIAMINO-6-ETHYLPYRIMIDIN-5-YL)-2-(3,5-DIFLUOROPHENYL)-4-(3-METHOXYPROPYL)-2-METHYL-2H-1,4-BENZOXAZIN-3(4H)-ONE | n/a | |
| 94 | P00797_UNL | UNL | n/a | |||||
| 95 | P00797_VYD | VYD | n/a | 70679349 | CHEMBL2204736 | (3S,5R)-5-{[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]methyl}-N-(3-methylbutyl)piperidine-3-carboxamide | n/a | |
| 96 | P00797_VYE | VYE | n/a | 70679350 | CHEMBL2220087 | (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-N-(3-methylbutyl)piperidine-3-carboxamide | n/a | |
| 97 | P00797_VYF | VYF | n/a | 70679351 | CHEMBL2220069 | (3S,5R)-5-[4-(2-chlorophenyl)-2,2-dimethyl-5-oxopiperazin-1-yl]-N-(2,6-dimethylheptan-4-yl)piperidine-3-carboxamide | n/a | |
| 98 | P00797_SSR | SSR | n/a | 44195154 | CHEMBL1236060 | 2-(3-fluoro-2-methylbenzyl)-4-methyl-1-phenyl-3-(piperazin-1-ylcarbonyl)-1H-indol-5-ol | n/a | |
| 99 | P00797_MXD | MXD | DB00350 | n/a | CHEMBL802 | Minoxidil | n/a | |
| 100 | P00797_LPR | LPR | DB00722 | 5362119;11865407;139146300; | CHEMBL1237 | Lisinopril | inhibitor | |
| 101 | P00797_DMF | DMF | DB01844 | 6228 | CHEMBL268291 | N,N-dimethylformamide | inhibitor | |
| 102 | P00797_DB02296 | n/a | DB02296 | n/a | n/a | Isoamyl alcohol | inhibitor | |
| 103 | P00797_DB02803 | n/a | DB02803 | n/a | n/a | 3-Phenyl-1,2-Propandiol | inhibitor | |
| 104 | P00797_DB03024 | n/a | DB03024 | n/a | n/a | 2-Methyl-3-(2-Aminothiazolo)Propanal | inhibitor | |
| 105 | P00797_DB03395 | n/a | DB03395 | n/a | n/a | Enalkiren | inhibitor | IC50(nM) = 0.75 |
| 106 | P00797_DB03736 | n/a | DB03736 | n/a | n/a | 2-Cyclopropylmethylenepropanal | inhibitor | |
| 107 | P00797_DB03968 | n/a | DB03968 | n/a | n/a | 1-Methyl-2-Oxy-5,5-Dimethyl Pyrrolidine | inhibitor | |
| 108 | P00797_DB04379 | n/a | DB04379 | n/a | n/a | N-Methyl-N-(Methylbenzyl)Formamide | inhibitor | |
| 109 | P00797_DB04387 | n/a | DB04387 | n/a | n/a | 1-Hydroxy-2-Amino-3-Cyclohexylpropane | inhibitor |