Gene name: PIK3CG
Protein name: Phosphatidylinositol 4,5-bisphosphate 3-kinase
List of molecules and drugs that interact with protein P48736
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P48736_039 | 039 | DB06831 | 6852165 | CHEMBL1213083 | 2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE | n/a | |
| 2 | P48736_090 | 090 | n/a | 6852166 | n/a | N-(2,3-DIHYDRO-7,8-DIMETHOXYIMIDAZO[1,2-C] QUINAZOLIN-5-YL)NICOTINAMIDE | n/a | |
| 3 | P48736_093 | 093 | DB06836 | 6852167 | CHEMBL1229535 | N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE | n/a | Ki(nM) = 7.0 IC50(nM) = 16.0 |
| 4 | P48736_0KO | 0KO | n/a | 49784894 | CHEMBL2165017 | 4-(2-[(6-methoxypyridin-3-yl)amino]-5-{[4-(methylsulfonyl)piperazin-1-yl]methyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine | n/a | |
| 5 | P48736_0SC | 0SC | n/a | 53378051 | CHEMBL2152768 | 2-(1-{[2-(5-fluoro-1H-indol-4-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol | n/a | |
| 6 | P48736_0SD | 0SD | n/a | 53378156 | CHEMBL2152770 | 2-(1-{[2-(2H-indazol-4-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol | n/a | |
| 7 | P48736_0SE | 0SE | n/a | 53378053 | CHEMBL2152771 | 2-(1-{[2-(2-aminopyrimidin-5-yl)-4-(morpholin-4-yl)pyrido[3,2-d]pyrimidin-6-yl]methyl}piperidin-4-yl)propan-2-ol | n/a | |
| 8 | P48736_0TA | 0TA | n/a | 59258964 | CHEMBL2057726 | 2-amino-8-cyclopentyl-4-methyl-6-(1H-pyrazol-4-yl)pyrido[2,3-d]pyrimidin-7(8H)-one | n/a | |
| 9 | P48736_0TB | 0TB | n/a | 59259014 | CHEMBL2057736 | 2-amino-6-(5-fluoro-6-methoxypyridin-3-yl)-4-methyl-8-(pyrrolidin-1-yl)pyrido[2,3-d]pyrimidin-7(8H)-one | n/a | |
| 10 | P48736_0TZ | 0TZ | n/a | 49835055 | CHEMBL2172637 | 3-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1H-pyrazol-5-yl)imidazo[1,2-a]pyridin-2-amine | n/a | |
| 11 | P48736_0U0 | 0U0 | n/a | 62706651 | CHEMBL2172630 | 3-[2-methyl-6-(pyrazin-2-ylamino)pyrimidin-4-yl]-N-(1H-pyrazol-3-yl)imidazo[1,2-b]pyridazin-2-amine | n/a | |
| 12 | P48736_0VU | 0VU | n/a | 60210977 | CHEMBL2158842 | 4-({4-[3-(piperidin-1-ylcarbonyl)phenyl]pyrimidin-2-yl}amino)benzenesulfonamide | n/a | |
| 13 | P48736_0W7 | 0W7 | n/a | 49855165;135566741; | CHEMBL2064419 | 2-[4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]-N-phenylacetamide | n/a | |
| 14 | P48736_0WR | 0WR | n/a | 59605870 | CHEMBL2171936 | 2-[1-({2-[2-(dimethylamino)-1H-benzimidazol-1-yl]-9-methyl-6-(morpholin-4-yl)-9H-purin-8-yl}methyl)piperidin-4-yl]propan-2-ol | n/a | |
| 15 | P48736_13K | 13K | n/a | 59507470 | CHEMBL2017978 | N~6~-(3,4-dimethoxyphenyl)-2-(morpholin-4-yl)-4,5'-bipyrimidine-2',6-diamine | n/a | |
| 16 | P48736_14K | 14K | n/a | 56947516 | CHEMBL2170081 | 4-(2-[(5-fluoro-6-methoxypyridin-3-yl)amino]-5-{(1R)-1-[4-(methylsulfonyl)piperazin-1-yl]ethyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine | n/a | |
| 17 | P48736_17V | 17V | n/a | 57900314 | CHEMBL2322764 | 2-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-4,5-dihydrothieno[3,2-d][1]benzoxepine-8-carboxamide | n/a | |
| 18 | P48736_19P | 19P | n/a | 46866705 | CHEMBL2331664 | 1-{1-[(2S)-2-hydroxypropanoyl]piperidin-4-yl}-3-methyl-8-(6-methylpyridin-3-yl)-1,3-dihydro-2H-imidazo[4,5-c][1,5]naphthyridin-2-one | n/a | |
| 19 | P48736_1JV | 1JV | n/a | 67061712 | CHEMBL2381379 | 2-methyl-1-(4-{2-[1-(2,2,2-trifluoroethyl)-1H-1,2,4-triazol-5-yl]-4,5-dihydro[1]benzoxepino[5,4-d][1,3]thiazol-8-yl}-1H-pyrazol-1-yl)propan-2-ol | n/a | |
| 20 | P48736_1UJ | 1UJ | n/a | 4416330 | CHEMBL2418960 | methyl 2-(acetylamino)-1,3-benzothiazole-6-carboxylate | n/a | |
| 21 | P48736_1UK | 1UK | n/a | 59251679 | CHEMBL2418954 | N-{6-[6-amino-5-(trifluoromethyl)pyridin-3-yl]imidazo[1,2-a]pyridin-2-yl}acetamide | n/a | |
| 22 | P48736_2NQ | 2NQ | n/a | 44608915 | CHEMBL1738719 | N-{2-chloro-5-[4-(morpholin-4-yl)quinolin-6-yl]pyridin-3-yl}-4-fluorobenzenesulfonamide | n/a | |
| 23 | P48736_2WH | 2WH | n/a | 73659199 | CHEMBL3356900 | 1-[6-(5-methoxypyridin-3-yl)-1,3-benzothiazol-2-yl]-3-[2-(1-propyl-1H-imidazol-4-yl)ethyl]urea | n/a | |
| 24 | P48736_2WJ | 2WJ | n/a | 44481151 | CHEMBL2418961 | N-[6-(pyridin-3-yl)-1,3-benzothiazol-2-yl]acetamide | n/a | |
| 25 | P48736_2WK | 2WK | n/a | 73659200 | CHEMBL3356889 | N-[6-(5,6-dimethoxypyridin-3-yl)-1,3-benzothiazol-2-yl]acetamide | n/a | |
| 26 | P48736_3PS | 3PS | n/a | 49852677 | n/a | 4-amino-N-(6-methoxypyridin-3-yl)-2-methylquinazoline-8-carboxamide | n/a | |
| 27 | P48736_3QH | 3QH | n/a | 121238095 | CHEMBL4561314 | 6-cyano-4-[[(1R)-1-(4-methylphenyl)ethyl]amino]quinoline-3-carboxamide | n/a | |
| 28 | P48736_3RE | 3RE | n/a | n/a | CHEMBL1614778 | 2-amino-8-(trans-4-methoxycyclohexyl)-4-methyl-6-(1H-pyrazol-3-yl)pyrido[2,3-d]pyrimidin-7(8H)-one | n/a | |
| 29 | P48736_3RZ | 3RZ | n/a | 49852676 | n/a | 4-amino-2-methyl-N-(1H-pyrazol-3-yl)quinazoline-8-carboxamide | n/a | |
| 30 | P48736_3T8 | 3T8 | n/a | 44242776 | CHEMBL1950037 | N~2~-{2-chloro-4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-N~2~,N~8~-dimethyl-4,5-dihydrothieno[3,2-d][1]benzoxepine-2,8-dicarboxamide | n/a | |
| 31 | P48736_3VC | 3VC | DB16879 | 68947304 | CHEMBL4303596 | N-{(1S)-1-[7-fluoro-2-(pyridin-2-yl)quinolin-3-yl]ethyl}-9H-purin-6-amine | n/a | |
| 32 | P48736_3VD | 3VD | n/a | 57707893 | n/a | N-{(1S)-1-[8-chloro-2-(3-fluorophenyl)quinolin-3-yl]ethyl}-9H-purin-6-amine | n/a | |
| 33 | P48736_3VE | 3VE | n/a | 25071294 | n/a | N-{(1S)-1-[8-chloro-2-(2-methylpyridin-3-yl)quinolin-3-yl]ethyl}-9H-purin-6-amine | n/a | |
| 34 | P48736_41A | 41A | DB07073 | 622262 | CHEMBL469099 | 5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benzothiazol-7(4H)-one | n/a | IC50(nM) = 1660.0 |
| 35 | P48736_43R | 43R | n/a | 46872177 | CHEMBL3586666 | N-[5-(5-methoxypyridin-3-yl)-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl]acetamide | n/a | |
| 36 | P48736_456 | 456 | n/a | 46872178 | CHEMBL3586670 | N-[5-(6-methoxypyrazin-2-yl)-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl]acetamide | n/a | |
| 37 | P48736_4FJ | 4FJ | n/a | 50939078 | CHEMBL2171931 | 1'-[7-fluoro-3-methyl-2-(pyridin-2-yl)quinolin-4-yl]-6'-(morpholin-4-yl)-1',2,2',3,5,6-hexahydrospiro[pyran-4,3'-pyrrolo[3,2-b]pyridine] | n/a | |
| 38 | P48736_534 | 534 | n/a | 56955955 | CHEMBL2152126 | 5-{3-[(4-{3-[4-(1-methylethyl)phenyl]pyrazin-2-yl}piperazin-1-yl)sulfonyl]phenyl}pyrimidin-2-amine | n/a | |
| 39 | P48736_5MT | 5MT | n/a | 58459197 | CHEMBL4788529 | 4-azanyl-6-[[(1~{S})-1-[6-fluoranyl-1-(3-methylsulfonylphenyl)benzimidazol-2-yl]ethyl]amino]pyrimidine-5-carbonitrile | n/a | |
| 40 | P48736_6E2 | 6E2 | DB12483 | 24989044 | CHEMBL3218576 | 2-azanyl-~{N}-[7-methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-yl]pyrimidine-5-carboxamide | inhibitor | |
| 41 | P48736_6K5 | 6K5 | n/a | 124220681 | n/a | [1-{4-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-6-(morpholin-4-yl)-1,3,5-triazin-2-yl}-3-(chloromethyl)azetidin-3-yl]methanol | n/a | |
| 42 | P48736_6K7 | 6K7 | n/a | 124220680 | n/a | [1-{4-[6-amino-4-(trifluoromethyl)pyridin-3-yl]-6-(morpholin-4-yl)pyrimidin-2-yl}-3-(chloromethyl)azetidin-3-yl]methanol | n/a | |
| 43 | P48736_6RF | 6RF | n/a | 49872646 | CHEMBL4449576 | 4-azanyl-6-[[(1~{S})-1-(6-fluoranyl-3-phenyl-4-piperazin-1-ylcarbonyl-quinolin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile | n/a | |
| 44 | P48736_74F | 74F | n/a | 126480568 | CHEMBL4090281 | 3-(benzotriazol-1-yl)-5-[1-methyl-5-[(1~{S})-1-morpholin-4-ylethyl]-1,2,4-triazol-3-yl]pyrazin-2-amine | n/a | |
| 45 | P48736_751 | 751 | n/a | 56955953 | CHEMBL2152124 | 2-{4-[(4'-METHOXYBIPHENYL-3-YL)SULFONYL]PIPERAZIN-1-YL}-3-(4-METHOXYPHENYL)PYRAZINE | n/a | |
| 46 | P48736_7L0 | 7L0 | n/a | 25128663 | CHEMBL2059907 | N-[6-(5-methylsulfonylpyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]ethanamide | n/a | |
| 47 | P48736_980 | 980 | DB12180 | 25254071 | CHEMBL1922094 | (2S)-1-(4-{[2-(2-aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}piperazin-1-yl)-2-hydroxypropan-1-one | modulator | |
| 48 | P48736_A3W | A3W | DB14846 | 58507717 | CHEMBL4084907 | 5-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)-4-(trifluoromethyl)pyridin-2-amine | inhibitor | |
| 49 | P48736_A82 | A82 | DB14980 | 44137675 | CHEMBL2165191 | 2-[[(1R)-1-(7-methyl-2-morpholin-4-yl-4-oxidanylidene-pyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoic acid | n/a | |
| 50 | P48736_ABJ | ABJ | DB07335 | 24905143 | CHEMBL1230790 | 3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL | n/a | |
| 51 | P48736_BMW | BMW | n/a | 24888922 | CHEMBL1684988 | 3-[7-(1H-benzimidazol-5-yl)-2-(morpholin-4-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]phenol | n/a | |
| 52 | P48736_BWY | BWY | n/a | 68313143 | CHEMBL4175041 | 10-[(S)-(1-tert-butylpiperidin-4-yl)sulfinyl]-2-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine | n/a | |
| 53 | P48736_BYM | BYM | DB07503 | 5287855 | CHEMBL1231533 | (5E)-5-[(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)METHYLENE]-1,3-THIAZOLIDINE-2,4-DIONE | inhibitor | |
| 54 | P48736_DD8 | DD8 | n/a | 134163712 | CHEMBL4169828 | 3-methyl-1-(oxan-4-yl)-8-pyridin-3-yl-imidazo[4,5-c]quinolin-2-one | n/a | |
| 55 | P48736_DW2 | DW2 | n/a | n/a | n/a | RU-PYRIDOCARBAZOLE-2 | n/a | |
| 56 | P48736_E52 | E52 | n/a | n/a | n/a | Methylated Ruthenium Pyridocarbazole | n/a | |
| 57 | P48736_EFV | EFV | n/a | 53327269 | CHEMBL4127784 | {4-[2-(5,6-dimethoxypyridin-3-yl)-5-oxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-1H-pyrazol-1-yl}acetonitrile | n/a | |
| 58 | P48736_EM7 | EM7 | n/a | 10357196 | CHEMBL2152125 | 3-AMINO-N-METHYL-6-[3-(1H-TETRAZOL-5-YL)PHENYL]PYRAZINE-2-CARBOXAMIDE | n/a | |
| 59 | P48736_F1S | F1S | n/a | 49785344 | CHEMBL2206907 | N-(5-{[3-(4-amino-6-methyl-1,3,5-triazin-2-yl)-5-(tetrahydro-2H-pyran-4-yl)pyridin-2-yl]amino}-2-chloropyridin-3-yl)methanesulfonamide | n/a | |
| 60 | P48736_FAV | FAV | n/a | 20877907 | CHEMBL1796267 | N-(2-chlorophenyl)-N-methyl-4H-thieno[3,2-c]chromene-2-carboxamide | n/a | |
| 61 | P48736_FAZ | FAZ | n/a | 44242428 | CHEMBL1796273 | 8-(acetylamino)-N-(2-chlorophenyl)-N-methyl-4,5-dihydrothieno[3,2-d][1]benzoxepine-2-carboxamide | n/a | |
| 62 | P48736_FJY | FJY | n/a | 50939209 | CHEMBL2171920 | 4-[3,3-dimethyl-6-(morpholin-4-yl)-2,3-dihydro-1H-indol-1-yl]-7-fluoro-3-methyl-2-(pyridin-3-yl)quinoline | n/a | |
| 63 | P48736_GD9 | GD9 | DB11663 | 17755052 | CHEMBL521851 | 2-(1H-indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-yl-thieno[3,2-d]pyrimidine | inhibitor | |
| 64 | P48736_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 65 | P48736_IGJ | IGJ | n/a | 146273897 | CHEMBL5170489 | 9-[(3~{R},4~{R})-4-fluoranylpyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one | n/a | |
| 66 | P48736_JZW | JZW | n/a | 44620964 | CHEMBL1085160 | [3-(6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenyl]methanol | n/a | |
| 67 | P48736_JZX | JZX | n/a | 44620965 | CHEMBL1083810 | 5-(6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)pyridin-2-amine | n/a | |
| 68 | P48736_JZY | JZY | n/a | 24946706 | CHEMBL1085177 | 4-methyl-5-(6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine | n/a | |
| 69 | P48736_L64 | L64 | n/a | 44182308 | CHEMBL540695 | 1-(4-{4-morpholin-4-yl-1-[1-(pyridin-3-ylcarbonyl)piperidin-4-yl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl}phenyl)-3-pyridin-4-ylurea | n/a | |
| 70 | P48736_LXX | LXX | n/a | 46174165 | n/a | 6-(1H-pyrazolo[3,4-b]pyridin-5-yl)-4-pyridin-4-ylquinoline | n/a | |
| 71 | P48736_M9T | M9T | n/a | n/a | CHEMBL4555040 | 2-[(4-methoxy-2-methyl-phenyl)amino]-7-methyl-9-(4-oxidanylcyclohexyl)purin-8-one | n/a | |
| 72 | P48736_MBW | MBW | DB16834 | 135151360 | CHEMBL4439259 | 7-methyl-2-[(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(oxan-4-yl)purin-8-one | n/a | |
| 73 | P48736_ML8 | ML8 | n/a | 45480167 | CHEMBL1234353 | 8-cyclopentyl-6-[3-(hydroxymethyl)phenyl]-4-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one | n/a | |
| 74 | P48736_ML9 | ML9 | DB11974 | n/a | CHEMBL1234354 | 2-amino-8-[trans-4-(2-hydroxyethoxy)cyclohexyl]-6-(6-methoxypyridin-3-yl)-4-methylpyrido[2,3-d]pyrimidin-7(8H)-one | modulator | |
| 75 | P48736_MMD | MMD | DB13051 | 49784945 | CHEMBL1684984 | 5-(7-Methanesulfonyl-2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-ylamine | modulator | |
| 76 | P48736_MMY | MMY | n/a | 24889936 | CHEMBL1684986 | 5-(2-Morpholin-4-yl-7-pyridin-3-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-ylamine | n/a | |
| 77 | P48736_NPZ | NPZ | DB08300 | 24905144 | CHEMBL1234815 | 1-methyl-3-naphthalen-2-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine | n/a | |
| 78 | P48736_NZS | NZS | n/a | 49817355 | CHEMBL1234877 | 6-(1,1-dioxidothiomorpholin-4-yl)-N-(3-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine | n/a | |
| 79 | P48736_NZU | NZU | n/a | 44181062 | CHEMBL1234878 | 6-(2H-indazol-4-yl)-1-methyl-N-[3-(methylsulfonyl)propyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine | n/a | |
| 80 | P48736_O92 | O92 | n/a | 56955954 | CHEMBL2152252 | 3-AMINO-6-{4-CHLORO-3-[(2,3-DIFLUOROPHENYL)SULFAMOYL]PHENYL}-N-METHYLPYRAZINE-2-CARBOXAMIDE | n/a | |
| 81 | P48736_OAW | OAW | n/a | 46891889 | CHEMBL1234917 | 2-amino-4-methyl-8-(1-methylethyl)-6-(1H-pyrazol-4-yl)pteridin-7(8H)-one | n/a | |
| 82 | P48736_P2B | P2B | n/a | 10405525 | CHEMBL1290743 | 3-[2-morpholin-4-yl-6-(pyridin-3-ylamino)pyrimidin-4-yl]phenol | n/a | |
| 83 | P48736_QAQ | QAQ | n/a | 50990922 | CHEMBL1615182 | [(4-{2-[(3-hydroxyphenyl)amino]-1H-benzimidazol-1-yl}-1,3,5-triazin-2-yl)amino]acetonitrile | n/a | |
| 84 | P48736_QAR | QAR | n/a | 46892845 | CHEMBL1615183 | 1-(4-amino-6-methyl-1,3,5-triazin-2-yl)-N-(1H-pyrazol-3-yl)-1H-benzimidazol-2-amine | n/a | |
| 85 | P48736_QJZ | QJZ | n/a | 25183031 | CHEMBL1615188 | N-{6-[2-(methylsulfanyl)pyrimidin-4-yl]-1,3-benzothiazol-2-yl}acetamide | n/a | |
| 86 | P48736_QK0 | QK0 | n/a | 50990924 | CHEMBL1615189 | N-[6-(6-chloro-5-{[(4-fluorophenyl)sulfonyl]amino}pyridin-3-yl)-1,3-benzothiazol-2-yl]acetamide | n/a | |
| 87 | P48736_QYT | QYT | DB04769 | 5289247 | CHEMBL568150 | (5E)-5-(QUINOXALIN-6-YLMETHYLENE)-1,3-THIAZOLIDINE-2,4-DIONE | inhibitor | |
| 88 | P48736_SD5 | SD5 | DB11666 | 16654980 | CHEMBL2017974 | 5-[2,6-di(morpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)pyridin-2-amine | inhibitor | |
| 89 | P48736_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 90 | P48736_V7Y | V7Y | DB16296 | 91933883 | CHEMBL3984425 | 2-amino-N-[(1S)-1-{8-[(1-methyl-1H-pyrazol-4-yl)ethynyl]-1-oxo-2-phenyl-1,2-dihydroisoquinolin-3-yl}ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide | inhibitor | |
| 91 | P48736_V81 | V81 | n/a | 154700581 | CHEMBL4782083 | 5-[2-amino-3-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-2-[(1S)-1-cyclopropylethyl]-7-(trifluoromethyl)-2,3-dihydro-1H-isoindol-1-one | n/a | |
| 92 | P48736_V84 | V84 | n/a | n/a | CHEMBL5190157 | 2-amino-5-{2-[(1S)-1-cyclopropylethyl]-7-methyl-1-oxo-2,3-dihydro-1H-isoindol-5-yl}-N-(trans-3-hydroxycyclobutyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide | n/a | |
| 93 | P48736_VL1 | VL1 | DB11896 | 44516953 | CHEMBL592445 | Gedatolisib | modulator | |
| 94 | P48736_VLV | VLV | n/a | 23585510 | CHEMBL2069328 | N~3~-{[5-(4-acetylphenyl)-4-methyl-1,3-thiazol-2-yl]carbamoyl}-N-tert-butyl-beta-alaninamide | n/a | |
| 95 | P48736_WJV | WJV | n/a | 49846369 | CHEMBL4753474 | N-[2-(3,3-dimethylbutoxy)ethyl]-N'-{4-methyl-5-[(pyridin-4-yl)ethynyl]-1,3-thiazol-2-yl}urea | n/a | |
| 96 | P48736_WYE | WYE | n/a | 44540644 | CHEMBL1094017 | (2Z)-4,6-dihydroxy-2-{[1-methyl-4-(4-methylpiperazin-1-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl]methylidene}-1-benzofuran-3(2H)-one | n/a | |
| 97 | P48736_WYF | WYF | n/a | 49867826 | n/a | (2Z)-4,6-dihydroxy-2-[(8-methoxy-1,2,3,4-tetrahydropyrazino[1,2-a]indol-10-yl)methylidene]-1-benzofuran-3(2H)-one | n/a | |
| 98 | P48736_XAZ | XAZ | n/a | 28063903 | CHEMBL1916048 | 5,7-dimethylpyrazolo[1,5-a]pyrimidin-2-amine | n/a | |
| 99 | P48736_ZIG | ZIG | DB12703 | 25167777 | CHEMBL1236962 | 2,4-difluoro-N-[2-methoxy-5-(4-pyridazin-4-ylquinolin-6-yl)pyridin-3-yl]benzenesulfonamide | modulator | |
| 100 | P48736_ZW3 | ZW3 | n/a | 54754350 | CHEMBL1914475 | N-{6-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]imidazo[1,2-a]pyridin-2-yl}acetamide | n/a | |
| 101 | P48736_STU | STU | DB02010 | 44259 | CHEMBL388978 | STAUROSPORINE | n/a | |
| 102 | P48736_MYC | MYC | DB02375 | 5281672 | CHEMBL164 | Myricetin | inhibitor | IC50(nM) = 1800.0 Kd(nM) = 170.0 |
| 103 | P48736_LY2 | LY2 | DB02656 | 3973 | CHEMBL98350 | LY-294002 | inhibitor | IC50(nM) = 940.0 Kd(nM) = 210.0 |
| 104 | P48736_QUE | QUE | DB04216 | 5280343 | CHEMBL50 | Quercetin | n/a | IC50(nM) = 3800.0 Kd(nM) = 280.0 |
| 105 | P48736_B6J | B6J | DB05552 | 10427712 | CHEMBL230011 | TG100-115 | inhibitor | |
| 106 | P48736_KWT | KWT | DB08059 | 312145 | CHEMBL428496 | Wortmannin | inhibitor | IC50(nM) = 5.0 Kd(nM) = 15.0 |
| 107 | P48736_DB11952 | n/a | DB11952 | n/a | n/a | Duvelisib | inhibitor | |
| 108 | P48736_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor |