Gene name: BACE1
Protein name: Beta-secretase 1 (EC
List of molecules and drugs that interact with protein P56817
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | P56817_009 | 009 | n/a | 24801865 | CHEMBL406317 | (4S)-1,4-dibenzyl-N-[(1S,2R)-1-benzyl-3-{[3-(dimethylamino)benzyl]amino}-2-hydroxypropyl]-2-oxoimidazolidine-4-carboxamide | n/a | |
| 2 | P56817_012 | 012 | n/a | 24801864 | CHEMBL261655 | (4S)-N-[(1S,2R)-1-benzyl-3-{[3-(dimethylamino)benzyl]amino}-2-hydroxypropyl]-1-(3-methoxybenzyl)-2-oxoimidazolidine-4-carboxamide | n/a | |
| 3 | P56817_038 | 038 | n/a | 49817351 | CHEMBL1229518 | 3-[[(2S)-2-[[[(2S)-2-[[(2S)-2-[[(2S)-2-azanyl-3-(1H-1,2,3,4-tetrazol-5-ylcarbonylamino)propanoyl]amino]-3-methyl-butanoyl]amino]-4-methyl-pentanoyl]amino]methyl]-2-hydroxy-4-phenyl-butanoyl]amino]benzoic acid | n/a | |
| 4 | P56817_091 | 091 | n/a | 56940703 | CHEMBL2181988 | (3S)-spiro[indole-3,3'-pyrrolidin]-2(1H)-one | n/a | |
| 5 | P56817_092 | 092 | n/a | 56940704 | CHEMBL2181997 | methyl (3S,5'R)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxylate | n/a | |
| 6 | P56817_095 | 095 | n/a | 56940705 | CHEMBL2181998 | tetrahydro-2H-pyran-4-yl (3S,5'R)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxylate | n/a | |
| 7 | P56817_09A | 09A | n/a | 56940706 | CHEMBL2181979 | benzyl (3S,5'R)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxylate | n/a | |
| 8 | P56817_09B | 09B | n/a | 56940707 | CHEMBL2181980 | 4-cyanobenzyl (3S,5'R)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxylate | n/a | |
| 9 | P56817_09D | 09D | n/a | 56940708 | n/a | (4S)-6-bromo-3,4-dihydro-2H-thiochromen-4-yl (3S,5'R)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxylate | n/a | |
| 10 | P56817_09E | 09E | n/a | 56940709 | n/a | (4S)-6-bromo-1,1-dioxido-3,4-dihydro-2H-thiochromen-4-yl (3S,5'R)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxylate | n/a | |
| 11 | P56817_09F | 09F | n/a | 56940710 | CHEMBL2181985 | 1-cyanocyclohexyl (3S,5'R)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxylate | n/a | |
| 12 | P56817_09G | 09G | n/a | 56940711 | CHEMBL2181982 | 3-bromo-4-cyanobenzyl (3S,5'R)-2-oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-5'-carboxylate | n/a | |
| 13 | P56817_0B1 | 0B1 | n/a | 66545743 | CHEMBL2169933 | 2-amino-6-[(1S,2R)-2-(3'-methoxybiphenyl-3-yl)cyclopropyl]-3-methylpyrimidin-4(3H)-one | n/a | |
| 14 | P56817_0B3 | 0B3 | n/a | 71737800 | CHEMBL3040447 | (6R)-2-amino-3,6-dimethyl-6-(2-phenylethyl)-5,6-dihydropyrimidin-4(3H)-one | n/a | |
| 15 | P56817_0B4 | 0B4 | n/a | 71737801 | CHEMBL3040534 | (6S)-2-amino-3,6-dimethyl-6-[(1R,2R)-2-phenylcyclopropyl]-5,6-dihydropyrimidin-4(3H)-one | n/a | |
| 16 | P56817_0B5 | 0B5 | n/a | 118440826 | CHEMBL4226994 | ~{N}-[3-[(4~{R},5~{R},6~{S})-2-azanyl-6-[1,1-bis(fluoranyl)ethyl]-5-fluoranyl-4-methyl-5,6-dihydro-1,3-oxazin-4-yl]-4-fluoranyl-phenyl]-5-(fluoranylmethoxy)pyrazine-2-carboxamide | n/a | |
| 17 | P56817_0B6 | 0B6 | n/a | 71466345 | CHEMBL4213486 | ~{N}-[3-[(4~{S})-2-azanyl-6-(fluoranylmethyl)-4-methyl-1,3-oxazin-4-yl]-4-fluoranyl-phenyl]-5-cyano-pyridine-2-carboxamide | n/a | |
| 18 | P56817_0BI | 0BI | n/a | 44631842 | CHEMBL595066 | (4S)-4-[(1R)-1-hydroxy-2-({1-[3-(1-methylethyl)phenyl]cyclopropyl}amino)ethyl]-19-(methoxymethyl)-11-oxa-3,16-diazatric yclo[15.3.1.1~6,10~]docosa-1(21),6(22),7,9,17,19-hexaen-2-one | n/a | |
| 19 | P56817_0EW | 0EW | n/a | 156612914 | CHEMBL5092328 | N-{3-[(2S,5R)-6-amino-5-(ethanesulfonyl)-2-(fluoromethyl)-5-methyl-2,3,4,5-tetrahydropyridin-2-yl]-4-fluorophenyl}-2,2-difluoro-2H-[1,3]dioxolo[4,5-c]pyridine-6-carboxamide | n/a | |
| 20 | P56817_0GH | 0GH | n/a | n/a | CHEMBL2179132 | N-[(2S)-1-({(2S,3R)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-3-phenylpropan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide | n/a | |
| 21 | P56817_0GO | 0GO | n/a | 66575075 | CHEMBL2047887 | (2S)-N-[(2S,3R)-3-hydroxy-1-phenyl-4-{[3-(propan-2-yl)benzyl]amino}butan-2-yl]-2-[(5S)-6-oxo-1-propyl-1,7-diazaspiro[4.4]non-7-yl]propanamide | n/a | |
| 22 | P56817_0GS | 0GS | n/a | 57386813 | CHEMBL2047891 | (3S,4S,5R)-3-(4-amino-3-bromo-5-fluorobenzyl)-5-{[3-(1,1-difluoroethyl)benzyl]amino}tetrahydro-2H-thiopyran-4-ol 1,1-dioxide | n/a | |
| 23 | P56817_0GT | 0GT | n/a | 57387067 | CHEMBL2047898 | (3R,4S,5S)-3-[(3-tert-butylbenzyl)amino]-5-{[3-(2,2-difluoroethyl)-1H-indol-5-yl]methyl}tetrahydro-2H-thiopyran-4-ol 1,1-dioxide | n/a | |
| 24 | P56817_0GU | 0GU | n/a | 57387070 | CHEMBL2047901 | (3R,4S,5S)-3-[(3-tert-butylbenzyl)amino]-5-[(4,4,7'-trifluoro-1',2'-dihydrospiro[cyclohexane-1,3'-indol]-5'-yl)methyl]tetrahydro-2H-thiopyran-4-ol 1,1-dioxide | n/a | |
| 25 | P56817_0K9 | 0K9 | n/a | 60202321 | CHEMBL2181911 | (2R)-N-{(2S,3R)-4-{[(4'S)-6'-(2,2-dimethylpropyl)-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl]amino}-3-hydroxy-1-[3-(1,3-thiazol-2-yl)phenyl]butan-2-yl}-2-methoxypropanamide | n/a | |
| 26 | P56817_0KK | 0KK | n/a | 15054176 | CHEMBL291784 | (2E)-2-imino-3-methyl-5,5-diphenylimidazolidin-4-one | n/a | |
| 27 | P56817_0KM | 0KM | n/a | 70681036 | CHEMBL2011981 | (2E,5R)-2-imino-5-(3'-methoxybiphenyl-3-yl)-3-methyl-5-phenylimidazolidin-4-one | n/a | |
| 28 | P56817_0KN | 0KN | n/a | 56940718 | CHEMBL2181880 | (2R)-N-[(2S,3R)-1-(1,3-benzodioxol-5-yl)-4-{[(4'S)-6'-(2,2-dimethylpropyl)-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl]amino}-3-hydroxybutan-2-yl]-2-methoxypropanamide | n/a | |
| 29 | P56817_0KP | 0KP | n/a | 70685236 | CHEMBL2011983 | (2E,5R)-2-imino-3-methyl-5-phenyl-5-[3-(pyridin-3-yl)phenyl]imidazolidin-4-one | n/a | |
| 30 | P56817_0KQ | 0KQ | n/a | 59388465 | CHEMBL2011965 | (2E,5R)-5-[3-(5-chloropyridin-3-yl)phenyl]-5-cyclopropyl-2-imino-3-methylimidazolidin-4-one | n/a | |
| 31 | P56817_0KR | 0KR | n/a | 57404339 | CHEMBL2012070 | (2E,5R)-5-cyclopropyl-2-imino-3-methyl-5-{3-[5-(prop-1-yn-1-yl)pyridin-3-yl]phenyl}imidazolidin-4-one | n/a | |
| 32 | P56817_0LG | 0LG | n/a | 57345931 | CHEMBL2047040 | N-[(4S,8E,11S)-4-[(1R)-1-hydroxy-2-{[3-(propan-2-yl)benzyl]amino}ethyl]-2,13-dioxo-11-phenyl-6-oxa-3,12-diazabicyclo[12.3.1]octadeca-1(18),8,14,16-tetraen-16-yl]-N-methylmethanesulfonamide | n/a | |
| 33 | P56817_0MP | 0MP | n/a | 60202322 | CHEMBL2030997 | N-((2S,3R)-1-(4-fluorophenyl)-3-hydroxy-4-((6'-neopentyl-3',4'-dihydrospiro[cyclobutane-1,2'-pyrano[2,3-b]pyridin]-4'-yl)amino)butan-2-yl)acetamide | n/a | |
| 34 | P56817_0N1 | 0N1 | n/a | 57345932 | CHEMBL2047045 | (4S,8E,11R)-4-[(1R)-1-hydroxy-2-{[3-(propan-2-yl)benzyl]amino}ethyl]-16-methyl-11-phenyl-6-oxa-3,12-diazabicyclo[12.3.1]octadeca-1(18),8,14,16-tetraene-2,13-dione | n/a | |
| 35 | P56817_0QQ | 0QQ | n/a | 162366968 | CHEMBL5075689 | N-[3-[(4R,5R,6R)-2-azanyl-5-fluoranyl-4,6-dimethyl-5,6-dihydro-1,3-thiazin-4-yl]-4-fluoranyl-phenyl]-2,3-dihydro-[1,4]dioxino[2,3-c]pyridine-7-carboxamide | n/a | |
| 36 | P56817_0U4 | 0U4 | n/a | 44123817 | CHEMBL510269 | N-[(2S,3R)-4-{[2-(1-benzylpiperidin-4-yl)ethyl]amino}-3-hydroxy-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide | n/a | |
| 37 | P56817_0UP | 0UP | n/a | 44514742 | CHEMBL2177470 | 4-{[(5R,7S)-1-(3-fluorophenyl)-3,7-dimethyl-2,2-dioxido-2-thia-1,3,8-triazaspiro[4.5]dec-8-yl]methyl}-2-(propan-2-yloxy)phenol | n/a | |
| 38 | P56817_0UQ | 0UQ | n/a | 58157954 | CHEMBL2177473 | (5R,7S)-1-(3-fluorophenyl)-3,7-dimethyl-8-[3-(propan-2-yloxy)benzyl]-2-thia-1,3,8-triazaspiro[4.5]decane 2,2-dioxide | n/a | |
| 39 | P56817_0V6 | 0V6 | n/a | 66575082 | CHEMBL2151181 | (2Z,6S)-6-{3-chloro-5-[5-(prop-1-yn-1-yl)pyridin-3-yl]thiophen-2-yl}-2-imino-3,6-dimethyltetrahydropyrimidin-4(1H)-one | n/a | |
| 40 | P56817_0VA | 0VA | n/a | 58962911 | CHEMBL2178178 | N-[N-(4-amino-3,5-dichlorobenzyl)carbamimidoyl]-3-(4-methoxyphenyl)-5-methyl-1,2-thiazole-4-carboxamide | n/a | |
| 41 | P56817_0VB | 0VB | n/a | 11983210 | CHEMBL2178181 | N-{N-[4-(acetylamino)-3-chloro-5-methylbenzyl]carbamimidoyl}-3-(4-methoxyphenyl)-5-methyl-1,2-thiazole-4-carboxamide | n/a | |
| 42 | P56817_0XA | 0XA | n/a | 71677787 | n/a | (4S,8E)-4-[(1R)-2-{[2-(5-tert-butyl-1,3-oxazol-2-yl)propan-2-yl]amino}-1-hydroxyethyl]-16-methyl-6-oxa-3-azabicyclo[12.3.1]octadeca-1(18),8,14,16-tetraene-2,13-dione | n/a | |
| 43 | P56817_0ZA | 0ZA | n/a | 70789278;135566781; | CHEMBL2346796 | 3-{(1S)-1-[(6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)amino]-2-phenylethyl}-1,2,4-oxadiazol-5(2H)-one | n/a | |
| 44 | P56817_10J | 10J | n/a | 60210990 | CHEMBL2178145 | 3-{5-[(2E,4aR,7aR)-6-benzoyl-2-imino-3-methyl-4-oxooctahydro-7aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophen-3-yl}benzonitrile | n/a | |
| 45 | P56817_10O | 10O | n/a | 66557874 | CHEMBL2178715 | 3-{5-[(2E,4aR,7aR)-2-imino-6-(6-methoxypyridin-2-yl)-3-methyl-4-oxooctahydro-7aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophen-3-yl}benzonitrile | n/a | |
| 46 | P56817_10Q | 10Q | n/a | 66557875 | CHEMBL2178713 | 2-{(2E,4aR,7aR)-7a-[4-(3-cyanophenyl)thiophen-2-yl]-2-imino-3-methyl-4-oxooctahydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl}pyridine-3-carbonitrile | n/a | |
| 47 | P56817_10V | 10V | n/a | 66557876 | CHEMBL2178712 | 3-{5-[(2E,4aR,7aR)-2-imino-6-(3-methoxypyridin-2-yl)-3-methyl-4-oxooctahydro-7aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophen-3-yl}benzonitrile | n/a | |
| 48 | P56817_10W | 10W | n/a | 60210991 | CHEMBL2178148 | 2-fluoro-5-{5-[(2E,4aR,7aR)-2-imino-3-methyl-4-oxo-6-phenyloctahydro-7aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophen-2-yl}benzonitrile | n/a | |
| 49 | P56817_13W | 13W | n/a | 11631207 | CHEMBL2151138 | 3-{5-[(2E,4S)-2-imino-1,4-dimethyl-6-oxohexahydropyrimidin-4-yl]thiophen-3-yl}benzonitrile | n/a | |
| 50 | P56817_18P | 18P | n/a | 53481984 | CHEMBL1923160 | N-{3-[(2R)-6-amino-2,4-dimethyl-3-oxo-2,3,4,5-tetrahydropyrazin-2-yl]phenyl}-5-chloropyridine-2-carboxamide | n/a | |
| 51 | P56817_1B1 | 1B1 | n/a | 137347946 | n/a | (2R)-2-cyclopropyl-5-methyl-2-[3-(5-prop-1-yn-1-ylpyridin-3-yl)phenyl]-2H-imidazol-4-amine | n/a | |
| 52 | P56817_1B7 | 1B7 | n/a | 71737824;135566782; | n/a | N-(6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-3-(4-propylthiophen-3-yl)-L-alanine | n/a | |
| 53 | P56817_1B8 | 1B8 | n/a | 70789279;135566783; | n/a | 3-[2-bromo-4-(1H-pyrazol-4-yl)thiophen-3-yl]-N-(6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-L-alanine | n/a | |
| 54 | P56817_1B9 | 1B9 | n/a | 70789281;135566785; | n/a | 3-(4-bromothiophen-3-yl)-N-(6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-L-alanine | n/a | |
| 55 | P56817_1BB | 1BB | n/a | 70789284;135566786; | CHEMBL2346802 | 2-{(1S)-1-[(6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)amino]-2-phenylethyl}-4-oxo-1,4-dihydropyrimidine-5-carbonitrile | n/a | |
| 56 | P56817_1BC | 1BC | n/a | 137347947 | n/a | 2-{(1S)-1-{[(1Z)-6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene]amino}-2-[2-propyl-4-(1H-pyrazol-4-yl)thiophen-3-yl]ethyl}pyrimidin-4(5H)-one | n/a | |
| 57 | P56817_1BE | 1BE | n/a | 70789287;135566788; | n/a | N-(6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-3-[2-propyl-4-(1H-pyrazol-4-yl)thiophen-3-yl]-L-alanine | n/a | |
| 58 | P56817_1BF | 1BF | n/a | 70789280;135566784; | n/a | N-(6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-3-[4-(1H-pyrazol-4-yl)thiophen-3-yl]-L-alanine | n/a | |
| 59 | P56817_1BL | 1BL | n/a | 70789282 | n/a | (2R)-5-{[(2S,3R)-4-{[1-(3-tert-butylphenyl)cyclohexyl]amino}-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]amino}-2-hydroxy-5-oxopentanoic acid | n/a | |
| 60 | P56817_1BS | 1BS | n/a | 70789285;135566787; | CHEMBL2346800 | 2-{(1S)-1-[(6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)amino]-2-phenylethyl}pyrido[4,3-d]pyrimidin-4(1H)-one | n/a | |
| 61 | P56817_1CH | 1CH | n/a | 824173;6947362;135532136; | n/a | N-(3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-L-phenylalanine | n/a | |
| 62 | P56817_1H5 | 1H5 | n/a | 66559017 | CHEMBL2347186 | N-{3-[(4S,5R)-2-amino-5-fluoro-4-(fluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide | n/a | |
| 63 | P56817_1H6 | 1H6 | n/a | 66558858 | CHEMBL2347205 | N-{3-[(4R,5S)-2-amino-5-fluoro-4-methyl-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide | n/a | |
| 64 | P56817_1H7 | 1H7 | n/a | 66558601 | CHEMBL2347204 | N-{3-[(4R,5R)-2-amino-5-fluoro-4-methyl-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide | n/a | |
| 65 | P56817_1H8 | 1H8 | n/a | 53241445 | CHEMBL2347203 | N-{3-[(4S)-2-amino-4-methyl-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide | n/a | |
| 66 | P56817_1HG | 1HG | n/a | 71305061 | CHEMBL2347188 | N-{3-[(4R,5R,6S)-2-amino-5-fluoro-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide | n/a | |
| 67 | P56817_1HH | 1HH | n/a | 71305060 | CHEMBL2347189 | N-{3-[(4R,5R,6R)-2-amino-5-fluoro-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide | n/a | |
| 68 | P56817_1HJ | 1HJ | n/a | 71305059 | CHEMBL2347207 | N-{3-[(4S,6R)-2-amino-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide | n/a | |
| 69 | P56817_1HL | 1HL | n/a | 71305058 | CHEMBL2347208 | N-{3-[(4S,6S)-2-amino-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide | n/a | |
| 70 | P56817_1HM | 1HM | n/a | 71305057 | CHEMBL2347187 | N-{3-[(4S,6S)-2-amino-4-(fluoromethyl)-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide | n/a | |
| 71 | P56817_1HO | 1HO | n/a | 71112644 | CHEMBL2347190 | N-{3-[(4S)-2-amino-5,5-difluoro-4-(fluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide | n/a | |
| 72 | P56817_1HQ | 1HQ | n/a | 71112763 | CHEMBL2347206 | N-{3-[(4S)-2-amino-4-(difluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide | n/a | |
| 73 | P56817_1LI | 1LI | n/a | 11754571 | CHEMBL571860 | N-[(1S,2R)-3-{[1-(3-tert-butylphenyl)cyclohexyl]amino}-1-(3,5-difluorobenzyl)-2-hydroxypropyl]acetamide | n/a | |
| 74 | P56817_1M4 | 1M4 | n/a | 137347967 | n/a | (4R)-2'-amino-6-bromo-1',2,2-trimethyl-2,3-dihydrospiro[chromene-4,4'-imidazol]-5'(1'H)-one | n/a | |
| 75 | P56817_1M5 | 1M5 | n/a | 137347968 | n/a | (4R)-2'-amino-6-(3-chlorophenyl)-1',2,2-trimethyl-2,3-dihydrospiro[chromene-4,4'-imidazol]-5'(1'H)-one | n/a | |
| 76 | P56817_1M6 | 1M6 | n/a | 137347969 | n/a | 3-[(4R)-2'-amino-1',2,2-trimethyl-5'-oxo-1',2,3,5'-tetrahydrospiro[chromene-4,4'-imidazol]-6-yl]benzonitrile | n/a | |
| 77 | P56817_1M7 | 1M7 | n/a | 66684136 | CHEMBL2349470 | (4R)-2-amino-1,3',3'-trimethyl-7'-(pyrimidin-5-yl)-3',4'-dihydro-2'H-spiro[imidazole-4,1'-naphthalen]-5(1H)-one | n/a | |
| 78 | P56817_1QT | 1QT | n/a | 71598542 | CHEMBL2407345 | (3S)-3-[(1R)-2-{[(4S)-6-ethyl-3,4-dihydrospiro[chromene-2,1'-cyclobutan]-4-yl]amino}-1-hydroxyethyl]-4-azabicyclo[11.3.1]heptadeca-1(17),13,15-trien-5-one | n/a | |
| 79 | P56817_1QU | 1QU | n/a | 71598543 | CHEMBL2407494 | 1-cyclopentyl-N-[(2S,3R)-3-hydroxy-1-phenyl-4-{[3-(trifluoromethyl)benzyl]amino}butan-2-yl]-6-oxo-5-(2-oxopyrrolidin-1-yl)-1,6-dihydropyridine-3-carboxamide | n/a | |
| 80 | P56817_1R6 | 1R6 | n/a | 71581445 | CHEMBL2407488 | (12S)-12-[(1R)-2-{[(4S)-6-ethyl-3,4-dihydrospiro[chromene-2,1'-cyclobutan]-4-yl]amino}-1-hydroxyethyl]-1,13-diazatricyclo[13.3.1.1~6,10~]icosa-6(20),7,9,15(19),16-pentaene-14,18-dione | n/a | |
| 81 | P56817_1R8 | 1R8 | n/a | 71581444 | CHEMBL2407344 | (3S)-3-[(1R)-2-{[(4S)-6-ethyl-3,4-dihydrospiro[chromene-2,1'-cyclobutan]-4-yl]amino}-1-hydroxyethyl]-4-azabicyclo[10.3.1]hexadeca-1(16),12,14-trien-5-one | n/a | |
| 82 | P56817_1SQ | 1SQ | n/a | 73742 | CHEMBL62083 | ISOQUINOLIN-1-AMINE | n/a | |
| 83 | P56817_1W0 | 1W0 | n/a | 72712537 | n/a | (3aS,7aR)-7a-[3-(pyrimidin-5-yl)phenyl]-3a,6,7,7a-tetrahydro-4H-pyrano[4,3-d][1,3]oxazol-2-amine | n/a | |
| 84 | P56817_1W1 | 1W1 | n/a | 137347998 | n/a | 2-[(3aR,7aR)-2-amino-7a-(2,4-difluorophenyl)-3a,6,7,7a-tetrahydro[1,3]oxazolo[5,4-c]pyridin-5(4H)-yl]pyridine-3-carbonitrile | n/a | |
| 85 | P56817_1W2 | 1W2 | n/a | 137347999 | n/a | 2-[(3aS,7aR)-2-amino-3a-(2,4-difluorophenyl)-3a,6,7,7a-tetrahydro[1,3]oxazolo[4,5-c]pyridin-5(4H)-yl]pyridine-3-carbonitrile | n/a | |
| 86 | P56817_1WP | 1WP | n/a | 72712745 | n/a | (3aR,7aR)-3a-[3-(5-chloropyridin-3-yl)phenyl]-3a,4,5,6,7,7a-hexahydro-1,3-benzoxazol-2-amine | n/a | |
| 87 | P56817_1YS | 1YS | n/a | 71664591 | CHEMBL2425608 | (1R,3S,4S,5R)-3-{4-amino-3-fluoro-5-[(1,1,1,3,3,3-hexafluoropropan-2-yl)oxy]benzyl}-5-[(3-tert-butylbenzyl)amino]tetrahydro-2H-thiopyran-4-ol 1-oxide | n/a | |
| 88 | P56817_1YT | 1YT | n/a | 51003469 | CHEMBL2425612 | (1R,3S,4S,5R)-3-(4-amino-3-fluoro-5-{[(2R)-1,1,1-trifluoro-3-methoxypropan-2-yl]oxy}benzyl)-5-[(3-tert-butylbenzyl)amino]tetrahydro-2H-thiopyran-4-ol 1-oxide | n/a | |
| 89 | P56817_1YU | 1YU | n/a | 71664592 | CHEMBL2425609 | (1S,3S,4S,5R)-3-{4-amino-3-fluoro-5-[(1,1,1,3,3,3-hexafluoropropan-2-yl)oxy]benzyl}-5-[(3-tert-butylbenzyl)amino]tetrahydro-2H-thiopyran-4-ol 1-oxide | n/a | |
| 90 | P56817_23I | 23I | n/a | 16659106 | CHEMBL387771 | N-[(1S,2S,4R)-2-HYDROXY-1-ISOBUTYL-5-({(1S)-1-[(ISOPROPYLAMINO)CARBONYL]-2-METHYLPROPYL}AMINO)-4-METHYL-5-OXOPENTYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N'-[(1R)-1-PHENYLETHYL]ISOPHTHALAMIDE | n/a | |
| 91 | P56817_251 | 251 | DB06930 | 11290116;137628959; | CHEMBL217068 | N-[amino(imino)methyl]-2-(2,5-diphenyl-1H-pyrrol-1-yl)acetamide | n/a | IC50(nM) = 3700.0 |
| 92 | P56817_2AQ | 2AQ | n/a | 11379 | CHEMBL61236 | QUINOLIN-2-AMINE | n/a | |
| 93 | P56817_2EX | 2EX | n/a | 56947421 | CHEMBL3127106 | (4R,4a'S,10a'S)-2-amino-8'-(2-fluoropyridin-3-yl)-1-methyl-3',4',4a',10a'-tetrahydro-1'H-spiro[imidazole-4,10'-pyrano[4,3-b]chromen]-5(1H)-one | n/a | |
| 94 | P56817_2FB | 2FB | n/a | 137348044 | n/a | (6R)-6-(4-methoxyphenyl)-2-methyl-6-(3-pyrimidin-5-ylphenyl)pyrrolo[3,4-d][1,3]thiazol-4-amine | n/a | |
| 95 | P56817_2LI | 2LI | n/a | 44537810 | n/a | N-[(1S,2R)-3-{[(5S)-5-(3-tert-butylphenyl)-4,5,6,7-tetrahydro-1H-indazol-5-yl]amino}-1-(3,5-difluorobenzyl)-2-hydroxypropyl]acetamide | n/a | |
| 96 | P56817_2X4 | 2X4 | n/a | 67950044 | CHEMBL3265330 | (4R,4a'S,10a'S)-7'-(5-chloropyridin-3-yl)-3',4',4a',10a'-tetrahydro-1'H-spiro[1,3-oxazole-4,5'-pyrano[3,4-b]chromen]-2-amine | n/a | |
| 97 | P56817_2X5 | 2X5 | n/a | 67950241 | CHEMBL3265335 | (4R,4a'R,10a'R)-7'-(5-chloropyridin-3-yl)-3',4',4a',10a'-tetrahydro-1'H-spiro[1,3-oxazole-4,5'-pyrano[3,4-b]chromen]-2-amine | n/a | |
| 98 | P56817_310 | 310 | n/a | 11583947;137348113; | CHEMBL253237 | N-carbamimidoyl-2-[2-(2-chlorophenyl)-5-[4-(4-ethanoylphenoxy)phenyl]pyrrol-1-yl]ethanamide | n/a | |
| 99 | P56817_314 | 314 | n/a | 24808496 | CHEMBL255194 | N'-[(1S,2R)-2-[(2R,4S)-4-benzylpiperidin-2-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | n/a | |
| 100 | P56817_316 | 316 | n/a | 24808497 | CHEMBL509210 | N'-[(1S,2S)-2-[(2S)-4-benzyl-3-oxopiperazin-2-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | n/a | |
| 101 | P56817_318 | 318 | n/a | 11520033 | CHEMBL507651 | N'-[(1S,2S)-2-[(4S)-1-benzyl-5-oxoimidazolidin-4-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | n/a | |
| 102 | P56817_32D | 32D | DB12368 | 46202416 | CHEMBL2177913 | (1S)-1-[2-(difluoromethyl)pyridin-4-yl]-4-fluoro-1-(3-pyrimidin-5-ylphenyl)-1H-isoindol-3-amine | n/a | |
| 103 | P56817_32P | 32P | n/a | 448772 | CHEMBL426717 | 3-{2-[(5-AMINOPENTYL)AMINO]-2-OXOETHOXY}-5-({[1-(4-FLUOROPHENYL)ETHYL]AMINO}CARBONYL)PHENYL PHENYLMETHANESULFONATE | n/a | |
| 104 | P56817_35A | 35A | DB07019 | 24768527 | n/a | N-[(5R,14R)-5-AMINO-5,14-DIMETHYL-4-OXO-3-OXA-18-AZATRICYCLO[15.3.1.1~7,11~]DOCOSA-1(21),7(22),8,10,17,19-HEXAEN-19-YL]-N-METHYLMETHANESULFONAMIDE | n/a | |
| 105 | P56817_3BN | 3BN | n/a | 5327063 | CHEMBL202602 | 3-BENZOYL-N-[(1S,2R)-1-BENZYL-3-(CYCLOPROPYLAMINO)-2-HYDROXYPROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]BENZAMIDE | n/a | |
| 106 | P56817_3HF | 3HF | n/a | 51000417 | n/a | N~3~-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-N~1~,N~1~-dibutyl-1H-indole-1,3-dicarboxamide | n/a | |
| 107 | P56817_3HH | 3HH | n/a | 51000418 | n/a | N~1~-butyl-5-cyano-N~3~-{(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-N~1~-methyl-1H-indole-1,3-dicarboxamide | n/a | |
| 108 | P56817_3J9 | 3J9 | n/a | 67950186 | CHEMBL3357661 | (4R,4a'S,10a'R)-8'-(2-fluoropyridin-3-yl)-4a'-methyl-3',4',4a',10a'-tetrahydro-2'H-spiro[1,3-oxazole-4,10'-pyrano[3,2-b]chromen]-2-amine | n/a | |
| 109 | P56817_3KO | 3KO | n/a | 118720056 | CHEMBL3354247 | (2E,5R)-5-(2-cyclohexylethyl)-5-{[(3R)-1-(cyclopentylacetyl)pyrrolidin-3-yl]methyl}-2-imino-3-methylimidazolidin-4-one | n/a | |
| 110 | P56817_3KT | 3KT | n/a | 57844200 | CHEMBL3354250 | (2E,5R)-5-(2-cyclohexylethyl)-5-{[(1S,3R)-3-(cyclopentylamino)cyclohexyl]methyl}-2-imino-3-methylimidazolidin-4-one | n/a | |
| 111 | P56817_3KU | 3KU | n/a | 11582999 | CHEMBL3354253 | N-[(1R,3S)-3-{[(2E,4R)-4-(2-cyclohexylethyl)-2-imino-1-methyl-5-oxoimidazolidin-4-yl]methyl}cyclohexyl]pyridine-4-carboxamide | n/a | |
| 112 | P56817_3KW | 3KW | n/a | 11568842 | n/a | (2E,5R)-5-(2-cyclohexylethyl)-2-imino-3-methyl-5-{[(1S,3R)-3-(quinolin-2-ylamino)cyclohexyl]methyl}imidazolidin-4-one | n/a | |
| 113 | P56817_3LL | 3LL | n/a | 45254510 | CHEMBL3359763 | (5S)-7-(2-fluoropyridin-3-yl)-3-[(3-methyloxetan-3-yl)ethynyl]spiro[chromeno[2,3-b]pyridine-5,4'-[1,3]oxazol]-2'-amine | n/a | |
| 114 | P56817_3LN | 3LN | n/a | 45256109 | CHEMBL3354688 | (4S)-2'-(2,2-dimethylpropoxy)-7'-(pyrimidin-5-yl)spiro[1,3-oxazole-4,9'-xanthen]-2-amine | n/a | |
| 115 | P56817_3LO | 3LO | n/a | 45254900 | CHEMBL3354718 | (4S)-2'-(3,6-dihydro-2H-pyran-4-yl)-4'-fluoro-7'-(2-fluoropyridin-3-yl)spiro[1,3-oxazole-4,9'-xanthen]-2-amine | n/a | |
| 116 | P56817_3MR | 3MR | n/a | 16741239 | CHEMBL244347 | (4S)-4-(2-AMINO-6-PHENOXYQUINAZOLIN-3(4H)-YL)-N,4-DICYCLOHEXYL-N-METHYLBUTANAMIDE | n/a | |
| 117 | P56817_3P5 | 3P5 | n/a | 24877631 | CHEMBL1614769 | (3S,4S,5R)-3-(3-bromo-4-hydroxybenzyl)-5-[(3-cyclopropylbenzyl)amino]tetrahydro-2H-thiopyran-4-ol 1,1-dioxide | n/a | |
| 118 | P56817_3RS | 3RS | n/a | 53346491 | CHEMBL1821728 | (2R)-3-[2-amino-6-(2-methylphenyl)quinolin-3-yl]-N-[(4R)-2,2-dimethyltetrahydro-2H-pyran-4-yl]-2-methylpropanamide | n/a | |
| 119 | P56817_3RU | 3RU | n/a | 53346495 | CHEMBL1821813 | 3-(2-aminoquinolin-3-yl)-N-(cyclohexylmethyl)propanamide | n/a | |
| 120 | P56817_3TO | 3TO | n/a | 44552610 | CHEMBL569654 | 3-[2-(3-{[(furan-2-ylmethyl)(methyl)amino]methyl}phenyl)ethyl]pyridin-2-amine | n/a | |
| 121 | P56817_3UT | 3UT | n/a | 53465141 | CHEMBL4564735 | (5S)-3-(5,6-dihydro-2H-pyran-3-yl)-1-fluoro-7-(2-fluoropyridin-3-yl)spiro[chromeno[2,3-c]pyridine-5,4'-[1,3]oxazol]-2'-amine | n/a | |
| 122 | P56817_3UW | 3UW | n/a | 56948072 | CHEMBL3357656 | (4S,4a'S,10a'R)-2-amino-8'-(2-fluoropyridin-3-yl)-1-methyl-3',4',4a',10a'-tetrahydro-2'H-spiro[imidazole-4,10'-pyrano[3,2-b]chromen]-5(1H)-one | n/a | |
| 123 | P56817_3UX | 3UX | n/a | 56947698 | CHEMBL3357659 | (4S,4a'R,10a'S)-2-amino-8'-(2-fluoropyridin-3-yl)-1,4a'-dimethyl-3',4',4a',10a'-tetrahydro-2'H-spiro[imidazole-4,10'-pyrano[3,2-b]chromen]-5(1H)-one | n/a | |
| 124 | P56817_3UY | 3UY | n/a | 67971215 | CHEMBL3357662 | (4R,4a'R,10a'S)-8'-(2-fluoropyridin-3-yl)-4a'-methyl-3',4',4a',10a'-tetrahydro-2'H-spiro[1,3-oxazole-4,10'-pyrano[3,2-b]chromen]-2-amine | n/a | |
| 125 | P56817_3VO | 3VO | n/a | 71268850 | CHEMBL3414706 | (4aR,8aS)-8a-(2,4-difluorophenyl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine | n/a | |
| 126 | P56817_3VP | 3VP | n/a | n/a | CHEMBL3414701 | (4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-(fluoromethyl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine | n/a | |
| 127 | P56817_3WP | 3WP | n/a | 90657111 | CHEMBL3414702 | (4S)-4-(2,4-difluorophenyl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine | n/a | |
| 128 | P56817_3YS | 3YS | DB12547 | 49837968 | CHEMBL2396989 | N-{3-[(4aS,7aS)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl}-5-fluoropyridine-2-carboxamide | n/a | |
| 129 | P56817_411 | 411 | n/a | 11606008;137629066; | CHEMBL252189 | 3-bromo-N-[4-[1-(2-carbamimidamido-2-oxo-ethyl)-5-phenyl-pyrrol-2-yl]phenyl]benzamide | n/a | |
| 130 | P56817_43K | 43K | n/a | 58466119 | CHEMBL3394057 | (5S)-7-(2-fluoropyridin-3-yl)-3-(2-fluoropyridin-4-yl)spiro[chromeno[2,3-c]pyridine-5,4'-[1,3]oxazol]-2'-amine | n/a | |
| 131 | P56817_454 | 454 | n/a | 11543843 | CHEMBL582044 | 8,8-diphenyl-2,3,4,8-tetrahydroimidazo[1,5-a]pyrimidin-6-amine | n/a | |
| 132 | P56817_462 | 462 | DB07089 | 11995761;137629174; | CHEMBL391087 | N-[amino(imino)methyl]-2-[2-(2-chlorophenyl)-4-(4-propoxyphenyl)-3-thienyl]acetamide | n/a | IC50(nM) = 590.0 |
| 133 | P56817_472 | 472 | n/a | 49866505 | n/a | (5S)-2-amino-3-methyl-5-pyridin-4-yl-5-(3-pyridin-3-ylphenyl)-3,5-dihydro-4H-imidazol-4-one | n/a | |
| 134 | P56817_4B2 | 4B2 | DB13065 | 44251605 | CHEMBL2333941 | (4S)-4-[2,4-difluoro-5-(pyrimidin-5-yl)phenyl]-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine | n/a | |
| 135 | P56817_4FP | 4FP | DB07110 | 3699841 | CHEMBL144527 | 4-(4-FLUOROBENZYL)PIPERIDINE | n/a | |
| 136 | P56817_4QA | 4QA | n/a | 58949967;136021259; | n/a | 4-(cyclohexylamino)-1-(3-fluorophenyl)-8-[3-(propan-2-yloxy)benzyl]-1,3,8-triazaspiro[4.5]dec-3-en-2-one | n/a | |
| 137 | P56817_4QD | 4QD | n/a | 66738014;136375305; | n/a | 8-(3-{[(2S)-1-aminopropan-2-yl]oxy}benzyl)-4-(cyclohexylamino)-1-(3-fluorophenyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one | n/a | |
| 138 | P56817_4QF | 4QF | n/a | 91267056;136652638; | n/a | (5R,7S)-8-benzyl-4-(cyclohexylamino)-1-(3-fluorophenyl)-7-methyl-1,3,8-triazaspiro[4.5]dec-3-en-2-one | n/a | |
| 139 | P56817_4RW | 4RW | n/a | 91799648 | n/a | (4aS,8aR)-4a,5,6,7,8,8a-hexahydro-4H-3,1-benzothiazin-2-amine | n/a | |
| 140 | P56817_4RX | 4RX | n/a | 71714118 | CHEMBL3586136 | N-[(4S,4aS,6S,8aR)-10-aminohexahydro-3H-4,8a-(epithiomethenoazeno)isochromen-6(1H)-yl]-3-chlorobenzamide | n/a | |
| 141 | P56817_4RY | 4RY | n/a | 91799650 | n/a | N-[(4aS,6S,8aR)-2-amino-5,6,7,8-tetrahydro-4a,8a-(methanooxymethano)-3,1-benzothiazin-6(4H)-yl]-3-chlorobenzamide | n/a | |
| 142 | P56817_4RZ | 4RZ | n/a | 91799649 | n/a | N-[(4aS,6S,8aR)-2-amino-4a,5,6,7,8,8a-hexahydro-4H-3,1-benzothiazin-6-yl]-3-chlorobenzamide | n/a | |
| 143 | P56817_508 | 508 | n/a | 54765328 | CHEMBL1934292 | (1R,4'S)-3,4-dihydro-2H-spiro[naphthalene-1,3'-pyrrolidin]-4'-yl[(2S,4R)-2,4-diphenylpiperidin-1-yl]methanone | n/a | |
| 144 | P56817_52K | 52K | n/a | 50991585 | CHEMBL3634122 | N-{3-[(3R)-5-amino-3-methyl-3,6-dihydro-2H-1,4-oxazin-3-yl]phenyl}-5-chloropyridine-2-carboxamide | n/a | |
| 145 | P56817_532 | 532 | n/a | 137348308 | n/a | (5S)-2-amino-3-methyl-5-[3-(pyridin-3-yl)phenyl]-5-(thiophen-3-yl)-3,5-dihydro-4H-imidazol-4-one | n/a | |
| 146 | P56817_54M | 54M | n/a | 137348310 | n/a | (5R)-5-(4-methoxyphenyl)-5-(3-pyrimidin-5-ylphenyl)-3,4-dihydropyrrol-2-amine | n/a | |
| 147 | P56817_569 | 569 | n/a | 11539562 | CHEMBL568115 | (5R)-2-amino-5-(4-fluoro-3-pyrimidin-5-ylphenyl)-3-methyl-5-[4-(trifluoromethoxy)phenyl]-3,5-dihydro-4H-imidazol-4-one | n/a | |
| 148 | P56817_586 | 586 | n/a | 44631838 | CHEMBL573106 | N-[4-(1-BENZYLCARBAMOYL-2-METHYL-PROPYLCARBAMOYL)-1-(3,5-DIFLUORO-PHENOXYMETHYL)-2-HYDROXY-4-METHOXY-BUTYL]-5-(METHANES ULFONYL-METHYL-AMINO)-N'-(1-PHENYLETHYL)-ISOPHTHALAMIDE | n/a | |
| 149 | P56817_591 | 591 | n/a | 137348324 | n/a | (5S)-2-amino-5-(1-ethyl-1H-pyrazol-4-yl)-3-methyl-5-[3-(pyrimidin-5-yl)phenyl]-3,5-dihydro-4H-imidazol-4-one | n/a | |
| 150 | P56817_593 | 593 | n/a | n/a | n/a | (5S)-2-amino-3-methyl-5-phenyl-5-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]-3,5-dihydro-4H-imidazol-4-one | n/a | |
| 151 | P56817_5E7 | 5E7 | n/a | 89836206 | n/a | N-[(2S,3R)-3-hydroxy-4-({(2S,3S)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide | n/a | |
| 152 | P56817_5HA | 5HA | n/a | 5287532 | CHEMBL378225 | N-[(1S,2R)-1-BENZYL-3-(CYCLOPROPYLAMINO)-2-HYDROXYPROPYL]-5-[METHYL(METHYLSULFONYL)AMINO]-N'-[(1R)-1-PHENYLETHYL]ISOPHTHALAMIDE | n/a | |
| 153 | P56817_5MS | 5MS | DB07175 | 25138203 | CHEMBL469117 | N-{2-methyl-5-[(6-phenylpyrimidin-4-yl)amino]phenyl}methanesulfonamide | n/a | IC50(nM) = 24000.0 |
| 154 | P56817_5QU | 5QU | n/a | 137348392 | n/a | (2~{R},4~{S},6~{S})-4-[2,4-bis(fluoranyl)-5-pyrimidin-5-yl-phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-1,3-thiazinan-2-amine | n/a | |
| 155 | P56817_5QV | 5QV | n/a | 90253366 | CHEMBL3427251 | (4~{S},6~{S})-4-[2,4-bis(fluoranyl)-5-pyrimidin-5-yl-phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine | n/a | |
| 156 | P56817_5T5 | 5T5 | n/a | 137348398 | n/a | [(1~{R},2~{R})-2-[(4~{S})-2-azanyl-4-[4-[bis(fluoranyl)methoxy]phenyl]-5~{H}-1,3-oxazol-4-yl]cyclopropyl]-(5-chloranylpyridin-3-yl)methanone | n/a | |
| 157 | P56817_5T6 | 5T6 | n/a | 44178082 | n/a | (4~{S})-4-[4-[bis(fluoranyl)methoxy]-3-methyl-phenyl]-4-[3-(5-chloranylpyridin-3-yl)phenyl]-5~{H}-1,3-oxazol-2-amine | n/a | |
| 158 | P56817_5T7 | 5T7 | n/a | 71009238 | n/a | (1~{R},2~{R})-2-[(4~{R})-2-azanyl-5,5-bis(fluoranyl)-4-methyl-6~{H}-1,3-oxazin-4-yl]-~{N}-(3-chloranylquinolin-8-yl)cyclopropane-1-carboxamide | n/a | |
| 159 | P56817_5T8 | 5T8 | n/a | 118703101 | n/a | (5~{R})-5-[3-[(3-chloranylquinolin-8-yl)amino]phenyl]-5-methyl-2,6-dihydro-1,4-oxazin-3-amine | n/a | |
| 160 | P56817_60S | 60S | n/a | 118796840 | CHEMBL3799879 | 5-{(2E,4aR,7aR)-6-[5-fluoro-4-methyl-6-(methylamino)pyrimidin-2-yl]-2-imino-3-methyl-4-oxooctahydro-7aH-pyrrolo[3,4-d]pyrimidin-7a-yl}thiophene-2-carbonitrile | n/a | |
| 161 | P56817_60T | 60T | n/a | 44467506 | CHEMBL3640258 | (2E,4aR,7aS)-7a-(2,6-difluorophenyl)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-2-imino-3-methyloctahydro-4H-pyrrolo[3,4-d]pyrimidin-4-one | n/a | |
| 162 | P56817_60U | 60U | n/a | 44479524 | CHEMBL3799339 | 5-[(2E,4aR,7aR)-6-(4-ethoxy-5-fluoro-6-methylpyrimidin-2-yl)-2-imino-3-methyl-4-oxooctahydro-7aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophene-2-carbonitrile | n/a | |
| 163 | P56817_60V | 60V | n/a | 44247586 | CHEMBL3798544 | 5-[(2E,4aR,7aR)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-2-imino-3-methyl-4-oxooctahydro-7aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophene-2-carbonitrile | n/a | |
| 164 | P56817_60W | 60W | n/a | 71492530 | CHEMBL3800286 | 3-{5-[(2E,4aR,7aR)-6-(5-fluoro-4-methoxypyrimidin-2-yl)-2-imino-3-methyl-4-oxooctahydro-7aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophen-3-yl}benzonitrile | n/a | |
| 165 | P56817_60X | 60X | n/a | 44467360 | CHEMBL3640290 | (2E,4aR,7aS)-7a-(2,4-difluorophenyl)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-2-imino-3-methyloctahydro-4H-pyrrolo[3,4-d]pyrimidin-4-one | n/a | |
| 166 | P56817_60Y | 60Y | n/a | 71457203 | CHEMBL2178718 | 3-{5-[(2E,4aR,7aR)-6-(5-fluoropyrimidin-2-yl)-2-imino-3-methyl-4-oxooctahydro-7aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophen-3-yl}benzonitrile | n/a | |
| 167 | P56817_625 | 625 | n/a | 11719190 | CHEMBL1089137 | 4-(4-{1-[(6-aminopyridin-2-yl)methyl]-5-(2-chlorophenyl)-1H-pyrrol-2-yl}phenoxy)butanenitrile | n/a | |
| 168 | P56817_66F | 66F | DB12285 | 51352361 | CHEMBL3301601 | N-{3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl}-5-fluoropyridine-2-carboxamide | inhibitor | |
| 169 | P56817_66H | 66H | n/a | 137348435 | n/a | N-{3-[(2E,4R)-2-imino-1-methyl-5-oxo-4-phenylimidazolidin-4-yl]phenyl}furan-2-carboxamide | n/a | |
| 170 | P56817_66J | 66J | n/a | 68111516 | CHEMBL3259832 | (3E,5S)-5-{3-chloro-5-[5-(prop-1-yn-1-yl)pyridin-3-yl]thiophen-2-yl}-2,5-dimethyl-1,2,4-thiadiazinan-3-imine 1,1-dioxide | n/a | |
| 171 | P56817_68J | 68J | n/a | 118797904 | CHEMBL3808441 | N-(1-{3-[2-(2-amino-3-{3-[(3,3-dimethylbutyl)amino]-3-oxopropyl}quinolin-6-yl)phenyl]prop-2-yn-1-yl}cyclopropyl)-4-fluorobenzamide | n/a | |
| 172 | P56817_68K | 68K | n/a | 118797905 | CHEMBL3809870 | N-(6-{2-[2-(2-amino-3-{3-[(3,3-dimethylbutyl)amino]-3-oxopropyl}quinolin-6-yl)phenyl]ethyl}pyridin-3-yl)-4-fluorobenzamide | n/a | |
| 173 | P56817_68L | 68L | n/a | 137348437 | CHEMBL4294221 | N-[(5S)-2'-amino-3-(5,6-dihydro-2H-pyran-3-yl)-5'H-spiro[1-benzopyrano[2,3-c]pyridine-5,4'-[1,3]oxazol]-7-yl]-5-chloropyridine-2-carboxamide | n/a | |
| 174 | P56817_68M | 68M | n/a | 53465991 | CHEMBL1821826 | (2R)-3-[2-amino-6-(3-methylpyridin-2-yl)quinolin-3-yl]-N-(3,3-dimethylbutyl)-2-methylpropanamide | n/a | |
| 175 | P56817_6BS | 6BS | n/a | 53236891 | CHEMBL3808672 | 3-[2-amino-6-(2-methylphenyl)quinolin-3-yl]-N-(3,3-dimethylbutyl)propanamide | n/a | |
| 176 | P56817_6IP | 6IP | DB07206 | 11586735 | CHEMBL221118 | 6-[2-(1H-INDOL-6-YL)ETHYL]PYRIDIN-2-AMINE | n/a | IC50(nM) = 94000.0 |
| 177 | P56817_6T6 | 6T6 | n/a | 60202319 | n/a | (2R)-2-methyl-5-phenyl-2-(3-pyridin-3-ylphenyl)-2,3-dihydro-1H-imidazol-4-amine | n/a | |
| 178 | P56817_6T9 | 6T9 | n/a | 71305034 | CHEMBL2347367 | 5-Ethoxy-pyridine-2-carboxylic acid [3-((R)-2-amino-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide | n/a | |
| 179 | P56817_6TG | 6TG | n/a | 49836033 | CHEMBL2180030 | (2S)-2-(4-methoxy-3,5-dimethylphenyl)-5-methyl-2-(3-pyrimidin-5-ylphenyl)-2H-imidazol-4-amine | n/a | |
| 180 | P56817_6WD | 6WD | n/a | 90253396 | CHEMBL4444341 | (4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-4-methyl-6-pyrimidin-5-yl-5,6-dihydro-1,3-thiazin-2-amine | n/a | |
| 181 | P56817_6WE | 6WE | n/a | 90253397 | CHEMBL4551234 | (4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine | n/a | |
| 182 | P56817_6Z0 | 6Z0 | n/a | 53241828 | CHEMBL2347215 | N-[3-[(4R)-2-azanylidene-5,5-bis(fluoranyl)-4-methyl-1,3-oxazinan-4-yl]-4-fluoranyl-phenyl]-5-cyano-pyridine-2-carboxamide | n/a | |
| 183 | P56817_712 | 712 | n/a | 16094313 | CHEMBL218451 | 3-({[(1R)-1-(4-FLUOROPHENYL)ETHYL]AMINO}CARBONYL)-5-[METHYL(METHYLSULFONYL)AMINO]BENZYL ALPHA-METHYL-D-PHENYLALANINATE | n/a | |
| 184 | P56817_74A | 74A | n/a | 45105269 | CHEMBL1097318 | N'-{(1S,2S)-1-(3,5-difluorobenzyl)-2-hydroxy-2-[(2R)-4-(phenylcarbonyl)piperazin-2-yl]ethyl}-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | n/a | |
| 185 | P56817_74B | 74B | n/a | 86762648 | CHEMBL3673194 | (4aR,6R,8aS)-8a-(2,4-difluoro-5-{[(2,2,2-trifluoroethyl)amino]methyl}phenyl)-6-(fluoromethyl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine | n/a | |
| 186 | P56817_757 | 757 | n/a | 49866564 | n/a | 5-[[(2S)-2-[[(3R,4S)-5-(3,5-difluorophenoxy)-3-hydroxy-4-[[3-(methyl-methylsulfonyl-amino)-5-[[(1R)-1-phenylethyl]carbamoyl]phenyl]carbonylamino]pentanoyl]amino]-3-methyl-butanoyl]amino]benzene-1,3-dicarboxylic acid | n/a | |
| 187 | P56817_779 | 779 | n/a | 57844259 | CHEMBL3354255 | 1-[(1R,3S)-3-{[(2E,4R)-4-(2-cyclohexylethyl)-2-imino-1-methyl-5-oxoimidazolidin-4-yl]methyl}cyclohexyl]-3-phenylurea | n/a | |
| 188 | P56817_7F3 | 7F3 | n/a | 46206292 | CHEMBL2177909 | (1S)-4-fluoro-1-(4-fluoro-3-pyrimidin-5-ylphenyl)-1-[2-(trifluoromethyl)pyridin-4-yl]-1H-isoindol-3-amine | n/a | |
| 189 | P56817_7H3 | 7H3 | n/a | 89576898 | CHEMBL3919597 | N-{3-[(4aR,7aR)-2-amino-4,4a,5,6-tetrahydro-7aH-furo[2,3-d][1,3]thiazin-7a-yl]-4-fluorophenyl}-5-bromopyridine-2-carboxamide | n/a | |
| 190 | P56817_7IP | 7IP | DB07245 | 11659487 | CHEMBL221170 | 6-[2-(3'-METHOXYBIPHENYL-3-YL)ETHYL]PYRIDIN-2-AMINE | n/a | IC50(nM) = 25000.0 |
| 191 | P56817_842 | 842 | n/a | 45486979 | CHEMBL572081 | N-[(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-({1-[3-(1H-pyrazol-1-yl)phenyl]cyclohexyl}amino)propyl]acetamide | n/a | |
| 192 | P56817_879 | 879 | n/a | 11561538 | CHEMBL1091999 | 6-({2-(2-chlorophenyl)-5-[4-(pyrimidin-5-yloxy)phenyl]-1H-pyrrol-1-yl}methyl)pyridin-2-amine | n/a | |
| 193 | P56817_8AP | 8AP | DB07281 | 10397869 | CHEMBL435747 | N~3~-BENZYLPYRIDINE-2,3-DIAMINE | n/a | IC50(nM) = 310000.0 |
| 194 | P56817_8IP | 8IP | DB07284 | 11701820 | CHEMBL220346 | N~3~-(3-PYRIDIN-3-YLBENZYL)PYRIDINE-2,3-DIAMINE | n/a | IC50(nM) = 100000.0 |
| 195 | P56817_8QV | 8QV | n/a | 137348743 | CHEMBL4284110 | (5S)-3-(3,6-dihydro-2H-pyran-4-yl)-7-[5-(prop-1-yn-1-yl)pyridin-3-yl]-5'H-spiro[1-benzopyrano[2,3-c]pyridine-5,4'-[1,3]oxazol]-2'-amine | n/a | |
| 196 | P56817_8T3 | 8T3 | n/a | 71571523 | CHEMBL2403773 | N-[3-[(1S,3S,6S)-5-azanyl-3-methyl-4-azabicyclo[4.1.0]hept-4-en-3-yl]-4-fluoranyl-phenyl]-5-chloranyl-pyridine-2-carbox amide | n/a | |
| 197 | P56817_8W4 | 8W4 | n/a | 126961340 | CHEMBL4065655 | N-{(1S,2S)-1-[(2S)-4-benzyl-3-oxopiperazin-2-yl]-1-hydroxy-3-phenylpropan-2-yl}-7-ethyl-1,3,3-trimethyl-2,2-dioxo-1,2,3,4-tetrahydro-2lambda~6~-[1,2,5]thiadiazepino[3,4,5-hi]indole-9-carboxamide | n/a | |
| 198 | P56817_916 | 916 | n/a | 72200932 | n/a | N-[(2S,3R)-4-{[(4S)-6-(2,2-dimethylpropyl)-2,2-dimethyl-3,4-dihydro-2H-thieno[2,3-b]pyran-4-yl]amino}-3-hydroxy-1-phenylbutan-2-yl]acetamide | n/a | |
| 199 | P56817_929 | 929 | n/a | 45277565 | CHEMBL1076902 | N-[(2S,3S,5R)-1-[(3,5-difluorophenyl)methoxy]-3-hydroxy-5-methyl-6-[[(2S)-3-methyl-1-oxo-1-(phenylmethylamino)butan-2-yl]amino]-6-oxo-hexan-2-yl]-5-(methyl-methylsulfonyl-amino)-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide | n/a | |
| 200 | P56817_954 | 954 | n/a | 118796839 | CHEMBL3797680 | 5-{(2E,4aR,7aR)-6-[5-fluoro-4-methyl-6-(methylsulfanyl)pyrimidin-2-yl]-2-imino-3-methyl-4-oxooctahydro-7aH-pyrrolo[3,4-d]pyrimidin-7a-yl}thiophene-2-carbonitrile | n/a | |
| 201 | P56817_957 | 957 | n/a | 46891887 | CHEMBL1230648 | N-[(1S,2R)-1-(3,5-difluorobenzyl)-3-({1-[4-(2,2-dimethylpropyl)thiophen-2-yl]cyclopropyl}amino)-2-hydroxypropyl]acetamide | n/a | |
| 202 | P56817_996 | 996 | n/a | 71608661 | n/a | N-[(2S,3R)-4-{[(4S)-2-(2,2-dimethylpropyl)-6,6-dimethyl-4,5,6,7-tetrahydro-2H-indazol-4-yl]amino}-3-hydroxy-1-phenylbutan-2-yl]acetamide | n/a | |
| 203 | P56817_9IP | 9IP | DB07303 | 11500493 | CHEMBL220396 | N~3~-[3-(5-METHOXYPYRIDIN-3-YL)BENZYL]PYRIDINE-2,3-DIAMINE | n/a | IC50(nM) = 40000.0 |
| 204 | P56817_AA9 | AA9 | n/a | 9939419 | CHEMBL1210359 | N-((1S,2R)-3-(((1S)-2-(CYCLOHEXYLAMINO)-1--METHYL-2-OXOETHYL)AMINO)-2-HYDROXY-1-(PHENYLMETHYL)PROPYL)-3-(ETHYLAMINO)-5-((METHYLSULFONYL)(PHENYL)AMINO)BENZAMIDE | n/a | |
| 205 | P56817_ACT | ACT | DB14511 | 175 | n/a | ACETATE ION | n/a | |
| 206 | P56817_AED | AED | DB07345 | 24748051 | CHEMBL404150 | 4-(2-aminoethyl)-2-cyclohexylphenol | n/a | Kd(nM) = 220000.0 |
| 207 | P56817_AEF | AEF | DB08841 | 5610 | CHEMBL11608 | 4-(2-aminoethyl)phenol | n/a | Kd(nM) = 2000000.0 |
| 208 | P56817_AEG | AEG | n/a | 12234986 | CHEMBL1230845 | 4-[(2R)-2-aminopropyl]phenol | n/a | |
| 209 | P56817_AEH | AEH | DB07346 | 24748050 | CHEMBL255750 | 4-(2-aminoethyl)-2-ethylphenol | n/a | Kd(nM) = 660000.0 |
| 210 | P56817_AFJ | AFJ | n/a | 25163980 | CHEMBL461606 | (2R,4S,5S)-N-butyl-4-hydroxy-2,7-dimethyl-5-{[N-(4-methylpentanoyl)-L-methionyl]amino}octanamide | n/a | |
| 211 | P56817_AR9 | AR9 | n/a | 25163981 | CHEMBL490304 | (2R,4S)-N-butyl-4-[(2S,5S,7R)-2,7-dimethyl-3,15-dioxo-1,4-diazacyclopentadecan-5-yl]-4-hydroxy-2-methylbutanamide | n/a | |
| 212 | P56817_AXF | AXF | n/a | 9547929 | CHEMBL210240 | (2R,4S)-N-BUTYL-4-HYDROXY-2-METHYL- 4-((E)-(4AS,12R,15S,17AS)-15-METHYL -14,17-DIOXO-2,3,4,4A,6,9,11,12,13, 14,15,16,17,17A-TETRADECAHYDRO-1H-5 ,10-DITHIA-1,13,16-TRIAZA-BENZOCYCL OPENTADECEN-12-YL)-BUTYRAMIDE | n/a | |
| 213 | P56817_AXQ | AXQ | n/a | 9547928 | CHEMBL377149 | {(E)-(3R,6S,9R)-3-[(1S,3R)-3-((S)-1 -BUTYLCARBAMOYL-2-METHYL-PROPYLCARB AMOYL)-1-HYDROXY-BUTYL]-6-METHYL-5, 8-DIOXO-1,11-DITHIA-4,7-DIAZA-CYCLO PENTADEC-13-EN-9-YL}-CARBAMIC ACID TERT-BUTYL ESTER | n/a | |
| 214 | P56817_AYH | AYH | n/a | 45259044 | CHEMBL1093388 | (1R,3S)-3-[1-(acetylamino)-1-methylethyl]-N-[(1S,2S,4R)-1-benzyl-5-(butylamino)-2-hydroxy-4-methyl-5-oxopentyl]cyclohexanecarboxamide | n/a | |
| 215 | P56817_B00 | B00 | n/a | 66545742 | CHEMBL2169926 | 2-amino-3-methyl-6-[(1S,2R)-2-phenylcyclopropyl]pyrimidin-4(3H)-one | n/a | |
| 216 | P56817_B02 | B02 | n/a | 66545744 | CHEMBL2169939 | 2-amino-3-methyl-6-[(1S,2R)-2-(3'-methylbiphenyl-4-yl)cyclopropyl]pyrimidin-4(3H)-one | n/a | |
| 217 | P56817_B35 | B35 | DB07415 | 42628075 | n/a | 4-[(1S)-1-(3-fluoro-4-methoxyphenyl)-2-(2-methoxy-5-nitrophenyl)ethyl]-1H-imidazol-2-amine | n/a | |
| 218 | P56817_B7E | B7E | n/a | 132068789 | CHEMBL4117925 | compound 28 | n/a | |
| 219 | P56817_B7T | B7T | n/a | n/a | CHEMBL4116294 | (1r,4r)-4-methoxy-6'-(5-methyl-3-pyridinyl)-3'H-dispiro[cyclohexane-1,2'-indene-1',4''-[1,3]oxazol]-2''-amine | n/a | |
| 220 | P56817_BAV | BAV | n/a | 25163982 | CHEMBL564010 | (3S,14R,16S)-16-[(1R)-1-hydroxy-2-{[3-(1-methylethyl)benzyl]amino}ethyl]-3,4,14-trimethyl-1,4-diazacyclohexadecane-2,5- dione | n/a | |
| 221 | P56817_BDJ | BDJ | n/a | 45484188 | CHEMBL572367 | (2Z)-3-(3-chlorobenzyl)-2-imino-5,5-dimethylimidazolidin-4-one | n/a | |
| 222 | P56817_BDO | BDO | n/a | 49866692 | n/a | (2Z,5R)-3-(3-chlorobenzyl)-2-imino-5-methyl-5-(2-methylpropyl)imidazolidin-4-one | n/a | |
| 223 | P56817_BDQ | BDQ | n/a | 49866693 | n/a | 1-(4-cyanophenyl)-3-(4-{[(2Z,4R)-2-imino-4-methyl-4-(2-methylpropyl)-5-oxoimidazolidin-1-yl]methyl}benzyl)urea | n/a | |
| 224 | P56817_BDV | BDV | n/a | 49866694 | n/a | 1-butyl-3-(4-{[(2Z,4R)-2-imino-4-methyl-4-(2-methylpropyl)-5-oxoimidazolidin-1-yl]methyl}benzyl)urea | n/a | |
| 225 | P56817_BDW | BDW | n/a | 11237963 | CHEMBL1231280 | (4S)-1-(4-{[(2Z,4R)-4-(2-cyclohexylethyl)-4-(cyclohexylmethyl)-2-imino-5-oxoimidazolidin-1-yl]methyl}benzyl)-4-propylimidazolidin-2-one | n/a | |
| 226 | P56817_BDX | BDX | n/a | 11232421 | CHEMBL583178 | (2E,5R)-5-(2-cyclohexylethyl)-5-(cyclohexylmethyl)-2-imino-3-methylimidazolidin-4-one | n/a | |
| 227 | P56817_BJC | BJC | n/a | 45259045 | n/a | (1R,3S)-N-[(1S,2R)-1-benzyl-2-hydroxy-3-{[3-(1-methylethyl)benzyl]amino}propyl]-3-[1-methyl-1-(2-oxopiperidin-1-yl)ethy l]cyclohexanecarboxamide | n/a | |
| 228 | P56817_BSD | BSD | n/a | 24882306 | CHEMBL403268 | N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide | n/a | |
| 229 | P56817_BUH | BUH | n/a | 88602735 | CHEMBL3670375 | ~{N}-[6-[(3~{R},6~{R})-5-azanyl-3,6-dimethyl-6-(trifluoromethyl)-2~{H}-1,4-oxazin-3-yl]-5-fluoranyl-pyridin-2-yl]-3-chloranyl-5-(trifluoromethyl)pyridine-2-carboxamide | n/a | |
| 230 | P56817_BX2 | BX2 | n/a | 16726085 | CHEMBL590730 | (5S)-2-amino-5-(2,6-diethylpyridin-4-yl)-3-methyl-5-(3-pyrimidin-5-ylphenyl)-3,5-dihydro-4H-imidazol-4-one | n/a | |
| 231 | P56817_BXD | BXD | n/a | 44625397 | CHEMBL2048051 | (3S,4S,5R)-3-(4-amino-3-{[(2R)-3-ethoxy-1,1,1-trifluoropropan-2-yl]oxy}-5-fluorobenzyl)-5-[(3-tert-butylbenzyl)amino]tetrahydro-2H-thiopyran-4-ol 1,1-dioxide | n/a | |
| 232 | P56817_BXQ | BXQ | n/a | 44625098 | CHEMBL2047912 | (3S,4S,5R)-3-{4-amino-3-fluoro-5-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]benzyl}-5-[(3-tert-butylbenzyl)amino]tetrahydro-2H-thiopyran-4-ol 1,1-dioxide | n/a | |
| 233 | P56817_C27 | C27 | DB07519 | 16040323 | CHEMBL239857 | (6R)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one | n/a | IC50(nM) = 80.0 |
| 234 | P56817_C44 | C44 | n/a | 23657803 | n/a | N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(1S)-1,2,3,4-tetrahydronaphthalen-1-ylamino]propyl}-3-(1,1-dioxido-1,2-thiazinan-2-yl)-5-(ethylamino)benzamide | n/a | |
| 235 | P56817_C6A | C6A | n/a | 56851695 | n/a | N-[(2S,3R)-4-{[(2R,4S)-2-cyclopropyl-6-(2,2-dimethylpropyl)-3,4-dihydro-2H-chromen-4-yl]amino}-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]acetamide | n/a | |
| 236 | P56817_C6R | C6R | n/a | 138857908 | CHEMBL4473080 | N-[3-[(4S,5R)-2-azanyl-4-methyl-5-phenyl-5,6-dihydro-1,3-thiazin-4-yl]-4-fluoranyl-phenyl]-5-(fluoranylmethoxy)pyrazine-2-carboxamide | n/a | |
| 237 | P56817_C6U | C6U | n/a | 50938551 | CHEMBL2347211 | N-[3-[(4S)-2-azanyl-4-methyl-5,6-dihydro-1,3-thiazin-4-yl]-4-fluoranyl-phenyl]-5-chloranyl-pyridine-2-carboxamide | n/a | |
| 238 | P56817_C7O | C7O | n/a | 138454796 | CHEMBL4465534 | N-[3-[(5R)-3-azanyl-5-methyl-9,9-bis(oxidanylidene)-2,9$l^{6}-dithia-4-azaspiro[5.5]undec-3-en-5-yl]-4-fluoranyl-phenyl]-5-(fluoranylmethoxy)pyrazine-2-carboxamide | n/a | |
| 239 | P56817_C7X | C7X | n/a | 138857909 | CHEMBL4463201 | N-[3-[(4S,5S)-2-azanyl-4-methyl-5-phenyl-5,6-dihydro-1,3-thiazin-4-yl]-4-fluoranyl-phenyl]-5-(fluoranylmethoxy)pyrazine-2-carboxamide | n/a | |
| 240 | P56817_C83 | C83 | n/a | 91971958 | CHEMBL4557670 | N-[3-[(4R,5R,6R)-2-azanyl-5-fluoranyl-4,6-dimethyl-5,6-dihydro-1,3-thiazin-4-yl]-4-fluoranyl-phenyl]-5-(fluoranylmethoxy)pyrazine-2-carboxamide | n/a | |
| 241 | P56817_C86 | C86 | n/a | 139600334 | n/a | N-[3-[(4S,6S)-2-azanyl-4-methyl-6-(trifluoromethyl)-5,6-dihydro-1,3-thiazin-4-yl]-4-fluoranyl-phenyl]-5-(fluoranylmethoxy)pyrazine-2-carboxamide | n/a | |
| 242 | P56817_C8C | C8C | DB07535 | 11651760;135424789; | CHEMBL236777 | 2-amino-6-[2-(1H-indol-6-yl)ethyl]pyrimidin-4(3H)-one | n/a | IC50(nM) = 86000.0 |
| 243 | P56817_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 244 | P56817_CM7 | CM7 | n/a | 11296859 | CHEMBL554349 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-{[3-(trifluoromethyl)benzyl]amino}propyl]-7-ethyl-1-methyl-3,4-dihydro-1H-[1,2,5]thiadiazepino[3,4,5-hi]indole-9-carboxamide 2,2-dioxide | n/a | |
| 245 | P56817_CM8 | CM8 | n/a | 24794397 | CHEMBL401473 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-{[3-(trifluoromethyl)benzyl]amino}propyl]-3-(1,1-dioxido-1,2-thiazinan-2-yl)-5-(ethylamino)benzamide | n/a | |
| 246 | P56817_CMZ | CMZ | DB07573 | 831616 | n/a | (2S)-1-(2,5-dimethylphenoxy)-3-morpholin-4-ylpropan-2-ol | n/a | IC50(nM) = 1000000.0 |
| 247 | P56817_CS5 | CS5 | n/a | 9916309 | CHEMBL221597 | N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE | n/a | |
| 248 | P56817_CS7 | CS7 | n/a | 11556254 | CHEMBL270359 | N'-[(1S,2R)-2-[(2R,4R)-4-(BENZYLOXY)PYRROLIDIN-2-YL]-1-(3,5-DIFLUOROBENZYL)-2-HYDROXYETHYL]-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE | n/a | |
| 249 | P56817_CS9 | CS9 | n/a | 11614083 | CHEMBL403727 | N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-2-[(2R,4R)-4-PHENOXYPYRROLIDIN-2-YL]ETHYL}-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE | n/a | |
| 250 | P56817_D8Y | D8Y | n/a | 44552609 | CHEMBL575232 | 3-[2-(3-chlorophenyl)ethyl]pyridin-2-amine | n/a | |
| 251 | P56817_D9W | D9W | n/a | 50913659 | CHEMBL3653341 | ~{N}-[3-[(3~{R})-5-azanyl-3-methyl-2,6-dihydro-1,4-oxazin-3-yl]phenyl]-5-bromanyl-pyridine-2-carboxamide | n/a | |
| 252 | P56817_DJS | DJS | n/a | 131800991 | CHEMBL4117641 | 2-{[(2S)-butan-2-yl]amino}-N-{(1R,2S)-1-hydroxy-3-phenyl-1-[(2R)-pyrrolidin-2-yl]propan-2-yl}-6-(methylsulfonyl)pyridine-4-carboxamide | n/a | |
| 253 | P56817_DJV | DJV | n/a | 131800992 | CHEMBL4116622 | N-[(1R,2S)-1-[(2R,4R)-4-(cyclohexylmethoxy)pyrrolidin-2-yl]-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl]acetamide | n/a | |
| 254 | P56817_DK7 | DK7 | n/a | 131800993 | CHEMBL4116001 | N-[(1S,2S)-1-[(3R,6R)-6-(cyclohexylmethoxy)morpholin-3-yl]-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl]acetamide | n/a | |
| 255 | P56817_DKJ | DKJ | n/a | 11669599 | CHEMBL4116547 | N-{(1S,2S)-3-(3,5-difluorophenyl)-1-[(3R,5S,6R)-6-(2,2-dimethylpropoxy)-5-methylmorpholin-3-yl]-1-hydroxypropan-2-yl}acetamide | n/a | |
| 256 | P56817_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 257 | P56817_DWA | DWA | n/a | 137349207 | n/a | (4R)-4-[3-(2-fluoropyridin-3-yl)phenyl]-4-(4-methoxyphenyl)-4,5-dihydro-1,3-oxazol-2-amine | n/a | |
| 258 | P56817_DWB | DWB | n/a | 45255110 | n/a | (4S)-2'-(5-chloro-2-fluorophenyl)-7'-methoxyspiro[1,3-oxazole-4,9'-xanthen]-2-amine | n/a | |
| 259 | P56817_DWD | DWD | n/a | 45256294 | CHEMBL2177343 | (4S)-2'-(2-methylpropoxy)-7'-(pyrimidin-5-yl)spiro[1,3-oxazole-4,9'-xanthen]-2-amine | n/a | |
| 260 | P56817_E4A | E4A | n/a | 67440750 | n/a | (4S)-19-acetyl-4-[(1R)-1-hydroxy-2-({1-[3-(propan-2-yl)phenyl]cyclopropyl}amino)ethyl]-11-oxa-3,16-diazatricyclo[15.3.1.1~6,10~]docosa-1(21),6(22),7,9,17,19-hexaen-2-one | n/a | |
| 261 | P56817_E4G | E4G | n/a | n/a | n/a | (4S)-4-[(1R)-1-hydroxy-2-({[3-(propan-2-yl)phenyl]methyl}amino)ethyl]-19-(2-oxopropoxy)-11,16-dioxa-3-azatricyclo[15.3.1.1~6,10~]docosa-1(21),6(22),7,9,17,19-hexaen-2-one | n/a | |
| 262 | P56817_E4J | E4J | n/a | 146048092 | n/a | 2-(butylamino)-N-[(2S,3S,5R)-6-(butylamino)-3-hydroxy-5-methyl-6-oxo-1-phenylhexan-2-yl]-6-methoxypyridine-4-carboxamide | n/a | |
| 263 | P56817_E4Y | E4Y | n/a | 68541056 | n/a | (2R,4S)-N-butyl-4-[(4S,6R)-16-ethoxy-12-ethyl-6-methyl-2,13-dioxo-3,12-diazabicyclo[12.3.1]octadeca-1(18),14,16-trien-4-yl]-4-hydroxy-2-methylbutanamide | n/a | |
| 264 | P56817_E51 | E51 | n/a | 69007077 | n/a | (2R,4S)-N-butyl-4-[(5S,8S,10R)-5,10-dimethyl-3,3,6-trioxo-3lambda~6~-thia-7-azabicyclo[11.3.1]heptadeca-1(17),13,15-trien-8-yl]-4-hydroxy-2-methylbutanamide | n/a | |
| 265 | P56817_E5A | E5A | n/a | 67375400 | n/a | (10S,13S)-13-[(1R)-1-hydroxy-2-({[3-(propan-2-yl)phenyl]methyl}amino)ethyl]-9,10-dimethyl-2-oxa-9,12-diazabicyclo[13.3.1]nonadeca-1(19),15,17-triene-8,11-dione | n/a | |
| 266 | P56817_E5D | E5D | n/a | 68538837 | n/a | (9R,11S)-3-ethyl-11-[(1R)-1-hydroxy-2-({[3-(propan-2-yl)phenyl]methyl}amino)ethyl]-9-methyl-3,12-diazabicyclo[12.3.1]octadeca-1(18),14,16-triene-2,13-dione | n/a | |
| 267 | P56817_E5P | E5P | n/a | 146048094 | n/a | (9R,11S)-11-[(1R)-1-hydroxy-2-({[3-(propan-2-yl)phenyl]methyl}amino)ethyl]-9-methyl-16-(1,3-oxazol-2-yl)-3-[(1R)-1-phenylethyl]-3,12-diazabicyclo[12.3.1]octadeca-1(18),14,16-triene-2,13-dione | n/a | |
| 268 | P56817_E5V | E5V | n/a | 146048095 | n/a | (4S)-4-{(S)-hydroxy[(3R,6R)-6-(methoxymethyl)morpholin-3-yl]methyl}-19-(methoxymethyl)-11-oxa-3,16-diazatricyclo[15.3.1.1~6,10~]docosa-1(21),6(22),7,9,17,19-hexaen-2-one | n/a | |
| 269 | P56817_E5Y | E5Y | n/a | 146048096 | n/a | (5S,8S,10R)-8-[(1R)-1-hydroxy-2-{[(5-propyl-1H-pyrazol-3-yl)methyl]amino}ethyl]-4,5,10-trimethyl-1-oxa-4,7-diazacyclohexadecane-3,6-dione | n/a | |
| 270 | P56817_E61 | E61 | n/a | 146048097 | n/a | (10S,12S)-12-[(1R)-1-hydroxy-2-({[3-(propan-2-yl)phenyl]methyl}amino)ethyl]-17-(methoxymethyl)-10-methyl-7-oxa-2,13-diazabicyclo[13.3.1]nonadeca-1(19),15,17-trien-14-one | n/a | |
| 271 | P56817_E6J | E6J | n/a | 69227323 | n/a | (4S)-4-[(1R)-1-hydroxy-2-({[3-(propan-2-yl)phenyl]methyl}amino)ethyl]-19-(methoxymethyl)-11,16-dioxa-3-azatricyclo[15.3.1.1~6,10~]docosa-1(21),6(22),7,9,17,19-hexaen-2-one | n/a | |
| 272 | P56817_E6M | E6M | n/a | 146048098 | n/a | (10R,12S)-12-[(1R)-1-hydroxy-2-({[3-(propan-2-yl)phenyl]methyl}amino)ethyl]-17-(methoxymethyl)-10-methyl-2,13-diazabicyclo[13.3.1]nonadeca-1(19),15,17-trien-14-one | n/a | |
| 273 | P56817_E6P | E6P | n/a | 146048100 | n/a | (10S,12S)-17-chloro-12-[(1R)-1-hydroxy-2-({[3-(propan-2-yl)phenyl]methyl}amino)ethyl]-10-methyl-7-oxa-2,13,18-triazabicyclo[13.3.1]nonadeca-1(19),15,17-trien-14-one | n/a | |
| 274 | P56817_E6S | E6S | n/a | 146048101 | n/a | (3S,14R,16S)-16-[1,1-dihydroxy-2-({[3-(propan-2-yl)phenyl]methyl}amino)ethyl]-3,4,14-trimethyl-1,4-diazacyclohexadecane-2,5-dione | n/a | |
| 275 | P56817_E6V | E6V | n/a | 42636932 | CHEMBL558488 | (3S,14R,16S)-16-[(1R)-2-{[(4S)-2,2-dimethyl-6-(propan-2-yl)-3,4-dihydro-2H-1-benzopyran-4-yl]amino}-1-hydroxyethyl]-3,4,14-trimethyl-1,4-diazacyclohexadecane-2,5-dione | n/a | |
| 276 | P56817_E6Y | E6Y | n/a | 68942945 | n/a | (5S,8S,10R)-8-[(1R)-2-{[1-(3-tert-butylphenyl)cyclopropyl]amino}-1-hydroxyethyl]-4,5,10-trimethyl-1-oxa-4,7-diazacyclohexadecane-3,6-dione | n/a | |
| 277 | P56817_E74 | E74 | n/a | 69224554 | n/a | (4S)-4-[(1R)-1-hydroxy-2-({[3-(propan-2-yl)phenyl]methyl}amino)ethyl]-18-methoxy-3,15,17-triazatricyclo[14.3.1.1~6,10~]henicosa-1(20),6(21),7,9,16,18-hexaen-2-one | n/a | |
| 278 | P56817_E77 | E77 | n/a | 146048106 | n/a | (4S)-4-[(1R)-1,2-dihydroxyethyl]-N,N-dimethyl-2-oxo-11,16-dioxa-3-azatricyclo[15.3.1.1~6,10~]docosa-1(21),6(22),7,9,17,19-hexaene-19-carboxamide | n/a | |
| 279 | P56817_E7A | E7A | n/a | 146048107 | n/a | (10R,12S)-12-[(1R)-1,2-dihydroxyethyl]-N,N,10-trimethyl-14-oxo-2-oxa-13-azabicyclo[13.3.1]nonadeca-1(19),15,17-triene-17-carboxamide | n/a | |
| 280 | P56817_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 281 | P56817_EJ7 | EJ7 | n/a | 90411858 | CHEMBL3693258 | N-{3-[(1R,5S,6R)-3-amino-5-methyl-2-oxa-4-azabicyclo[4.1.0]hept-3-en-5-yl]-4-fluorophenyl}-5-methoxypyrazine-2-carboxamide | n/a | |
| 282 | P56817_EV0 | EV0 | n/a | 22394971;135556691; | CHEMBL235825 | 2-amino-6-propylpyrimidin-4(3H)-one | n/a | |
| 283 | P56817_EV2 | EV2 | n/a | 2041326 | CHEMBL1232596 | 3-pyrrolidin-1-ylquinoxalin-2-amine | n/a | |
| 284 | P56817_EV3 | EV3 | n/a | 2950966 | CHEMBL1221922 | 3-(2-amino-5-chloro-1H-benzimidazol-1-yl)propan-1-ol | n/a | |
| 285 | P56817_EV4 | EV4 | n/a | 46238535 | CHEMBL1221977 | 4-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-cyclohexyl-N-methylbutanamide | n/a | |
| 286 | P56817_EV5 | EV5 | n/a | 46238536 | CHEMBL1222240 | (3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(cyclohexylmethyl)pentanamide | n/a | |
| 287 | P56817_EV6 | EV6 | n/a | n/a | n/a | (3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-[(1R,3S,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-2-yl]pentanamide | n/a | |
| 288 | P56817_F1H | F1H | DB07734 | 25134249 | n/a | N-(1-benzylpiperidin-4-yl)-4-sulfanylbutanamide | n/a | |
| 289 | P56817_F1I | F1I | DB07735 | 25134250 | n/a | N-[1-(2,6-dimethoxybenzyl)piperidin-4-yl]-4-sulfanylbutanamide | n/a | |
| 290 | P56817_F1J | F1J | DB07736 | 25134251 | n/a | (2S)-4-(4-fluorobenzyl)-N-(2-sulfanylethyl)piperazine-2-carboxamide | n/a | |
| 291 | P56817_F1K | F1K | DB07737 | 25134252 | n/a | (2S)-4-(4-fluorobenzyl)-N-(3-sulfanylpropyl)piperazine-2-carboxamide | n/a | |
| 292 | P56817_F1L | F1L | DB07738 | 25134253 | n/a | N-[1-(5-bromo-2,3-dimethoxybenzyl)piperidin-4-yl]-4-sulfanylbutanamide | n/a | |
| 293 | P56817_F1M | F1M | n/a | 25134254 | n/a | N-{1-[5-chloro-3-methoxy-2-(1-methylethoxy)benzyl]piperidin-4-yl}-2-(4-sulfamoylphenoxy)acetamide | n/a | |
| 294 | P56817_F1N | F1N | n/a | 25134255 | n/a | N-{1-[5-chloro-3-methoxy-2-(1-methylethoxy)benzyl]piperidin-4-yl}-2-(2-methyl-4-sulfamoylphenoxy)acetamide | n/a | |
| 295 | P56817_F2I | F2I | n/a | 11628951 | CHEMBL373533 | N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-[(3-IODOBENZYL)AMINO]PROPYL}-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE | n/a | |
| 296 | P56817_FRP | FRP | n/a | 5494423 | CHEMBL200077 | N1-((2S,3S,5R)-3-AMINO-6-(4-FLUOROPHENYLAMINO)-5-METHYL-6-OXO-1-PHENYLHEXAN-2-YL)-N3,N3-DIPROPYLISOPHTHALAMIDE | n/a | |
| 297 | P56817_G00 | G00 | n/a | 1609819 | CHEMBL568966 | 4-butoxy-3-chlorobenzyl imidothiocarbamate | n/a | |
| 298 | P56817_GHJ | GHJ | n/a | 137349429 | n/a | (3R,3aR,6aS)-N-[(4R,7S,8S,10R,13S)-8-hydroxy-10,17-dimethyl-7-(2-methylpropyl)-5,11,14-trioxo-13-(propan-2-yl)-2-thia-6,12,15-triazaoctadecan-4-yl]hexahydrofuro[3,2-d][1,2]oxazole-3-carboxamide | n/a | |
| 299 | P56817_GMF | GMF | n/a | 71627364 | n/a | 2-[[3-(3-methoxyphenyl)phenyl]-(4-pyridyl)methyl]guanidine | n/a | |
| 300 | P56817_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 301 | P56817_GTU | GTU | n/a | 118399583 | CHEMBL4852444 | N-[3-[(4R)-2-azanyl-4-prop-1-ynyl-5,6-dihydro-1,3-oxazin-4-yl]-4-fluoranyl-phenyl]-5-cyano-pyridine-2-carboxamide | n/a | |
| 302 | P56817_GUC | GUC | n/a | 156022485 | n/a | N-[3-[(3S)-1-azanyl-5-fluoranyl-3-methyl-4H-2,6-naphthyridin-3-yl]-4-fluoranyl-phenyl]-5-cyano-3-methyl-pyridine-2-carboxamide | n/a | |
| 303 | P56817_GX6 | GX6 | n/a | 155818878 | n/a | N-[3-[(9S)-7-azanyl-2,2-bis(fluoranyl)-9-prop-1-ynyl-6-oxa-8-azaspiro[3.5]non-7-en-9-yl]-4-fluoranyl-phenyl]-5-cyano-pyridine-2-carboxamide | n/a | |
| 304 | P56817_H24 | H24 | DB07874 | 17749735 | CHEMBL1233206 | (6S)-2-amino-6-(3'-methoxybiphenyl-3-yl)-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one | n/a | |
| 305 | P56817_H3C | H3C | DB15307 | 68254185 | CHEMBL3916243 | N-[3-[(4S)-2-azanyl-4-methyl-1,3-thiazin-4-yl]-4-fluoranyl-phenyl]-5-cyano-pyridine-2-carboxamide | n/a | |
| 306 | P56817_HRV | HRV | n/a | 139030249 | n/a | N-{3-[(2R,3R)-5-amino-3-methyl-2-(trifluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl]-4-fluorophenyl}-3,5-dichloropyridine-2-carboxamide | n/a | |
| 307 | P56817_I02 | I02 | n/a | 11692473 | CHEMBL219601 | 3-{5-[(1R)-1-AMINO-1-METHYL-2-PHENYLETHYL]-1,3,4-OXADIAZOL-2-YL}-N-[(1R)-1-(4-FLUOROPHENYL)ETHYL]-5-[METHYL(METHYLSULFONYL)AMINO]BENZAMIDE | n/a | |
| 308 | P56817_I03 | I03 | n/a | 11963550 | n/a | (2S)-2-AMINO-2-BENZYL-3-HYDROXYPROPYL 3-({[(1R)-1-(4-FLUOROPHENYL)ETHYL]AMINO}CARBONYL)-5-[METHYL(METHYLSULFONYL)AMINO]BENZOATE | n/a | |
| 309 | P56817_I21 | I21 | n/a | 163184952 | n/a | 2-[(5R)-5-amino-5-methyl-4,16-dioxo-14-phenyl-3-oxa-15-azatricyclo[15.3.1.1~7,11~]docosa-1(21),7(22),8,10,12,14,17,19-octaen-19-yl]benzonitrile | n/a | |
| 310 | P56817_I6X | I6X | n/a | 57406537 | CHEMBL2152903 | 5-{(1R)-3-amino-4-fluoro-1-[3-(5-prop-1-yn-1-ylpyridin-3-yl)phenyl]-1H-isoindol-1-yl}-1-ethyl-3-methylpyridin-2(1H)-one | n/a | |
| 311 | P56817_III | III | n/a | 52108499 | n/a | ~{N},~{N}-dimethyl-2-pyrrolidin-1-yl-quinazolin-4-amine | n/a | |
| 312 | P56817_IOD | IOD | n/a | 30165 | n/a | IODIDE ION | n/a | |
| 313 | P56817_IP6 | IP6 | DB07993 | 11507920 | CHEMBL220896 | N~3~-[3-(1H-INDOL-6-YL)BENZYL]PYRIDINE-2,3-DIAMINE | n/a | IC50(nM) = 9100.0 |
| 314 | P56817_IP7 | IP7 | DB07994 | 11633167 | CHEMBL220428 | N~3~-[5-(1H-INDOL-6-YL)-2-(PYRIDIN-2-YLMETHOXY)BENZYL]PYRIDINE-2,3-DIAMINE | n/a | IC50(nM) = 4200.0 |
| 315 | P56817_IPA | IPA | DB02325 | 3776 | CHEMBL582 | ISOPROPYL ALCOHOL | n/a | |
| 316 | P56817_IXS | IXS | n/a | 23644701 | CHEMBL379513 | N-[(1S)-1-benzyl-2-{[(1S)-2-(isobutylamino)-1-methyl-2-oxoethyl]amino}ethyl]-N'-[(1R)-1-(4-fluorophenyl)ethyl]-5-[methyl(methylsulfonyl)amino]isophthalamide | n/a | |
| 317 | P56817_KGG | KGG | n/a | 71681797 | n/a | (3R,5R)-3-methoxy-5-(4-methoxyphenyl)-5-(3-pyridin-3-ylphenyl)-3,4-dihydropyrrol-2-amine | n/a | |
| 318 | P56817_L00 | L00 | n/a | 17749716 | CHEMBL1088070 | (2R)-2-(5-{3-chloro-6-((2-methoxyethyl){[(1S,2S)-2-methylcyclopropyl]methyl}amino)-2-[methyl(methylsulfonyl)amino]pyrid in-4-yl}-1,3,4-oxadiazol-2-yl)-1-phenylpropan-2-amine | n/a | |
| 319 | P56817_L01 | L01 | n/a | 449107 | CHEMBL443239 | 3-[({(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}AMINO)(HYDROXY)METHYL]-N,N-DIPROPYLBENZAMIDE | n/a | |
| 320 | P56817_L3J | L3J | n/a | n/a | n/a | (E)-N-(2-methylpropylidene)-N~2~-{[(4S)-17-[(methylsulfonyl)(propyl)amino]-2-oxo-3-azatricyclo[13.3.1.1~6,10~]icosa-1(19),6(20),7,9,15,17-hexaen-4-yl]methyl}-D-threoninamide | n/a | |
| 321 | P56817_L3M | L3M | n/a | 139209087 | n/a | (3S)-3-hydroxy-N-(2-methylpropyl)-N~2~-{[(4S)-17-[(methylsulfonyl)(propyl)amino]-2-oxo-3-azatricyclo[13.3.1.1~6,10~]icosa-1(19),6(20),7,9,15,17-hexaen-4-yl]methyl}-L-norleucinamide | n/a | |
| 322 | P56817_L4J | L4J | n/a | 11606910 | CHEMBL385374 | N-(2-methylpropyl)-N~2~-{[(4S)-17-[(methylsulfonyl)(propyl)amino]-2-oxo-3-azatricyclo[13.3.1.1~6,10~]icosa-1(19),6(20),7,9,15,17-hexaen-4-yl]methyl}-L-norleucinamide | n/a | |
| 323 | P56817_LIJ | LIJ | n/a | 15942666 | n/a | BENZYL [(1S)-2-({(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}AMINO)-2-OXO-1-{[(1-PROPYLBUTYL)SULFONYL]METHYL}ETHYL]CARBAMATE | n/a | |
| 324 | P56817_LIQ | LIQ | n/a | 15942667 | n/a | N-{(1S)-2-({(1S,2R)-1-(3,5-DIFLUOROBENZYL)-3-[(3-ETHYLBENZYL)AMINO]-2-HYDROXYPROPYL}AMINO)-2-OXO-1-[(PENTYLSULFONYL)METHYL]ETHYL}NICOTINAMIDE | n/a | |
| 325 | P56817_LPD | LPD | n/a | 111306 | CHEMBL1222059 | L-PROLINAMIDE | n/a | |
| 326 | P56817_M7D | M7D | n/a | 90656190 | CHEMBL3261075 | N-{3-[(3R)-1-amino-3-methyl-3,4-dihydropyrrolo[1,2-a]pyrazin-3-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide | n/a | |
| 327 | P56817_MMI | MMI | DB02378 | 449218 | CHEMBL362592 | N-[(4S,5S,7R)-8-({(S)-1-[(BENZYLAMINO)OXOMETHYL]-2-METHYLPROPYL}AMINO)-5-HYDROXY-2,7-DIMETHYL-8-OXO-OCT-4-YL]-(4S,7S)-4 -ISOPROPYL-2,5,9-TRIOXO-1-OXA-3,6,10-TRIAZACYCLOHEXADECANE-7-CARBOXAMIDE | n/a | |
| 328 | P56817_MR0 | MR0 | n/a | 16129583 | CHEMBL396765 | N~3~-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-N~1~,N~1~-DIPROPYLBENZENE-1,3,5-TRICARBOXAMIDE | n/a | |
| 329 | P56817_MV7 | MV7 | n/a | 25157024 | CHEMBL591644 | N-[(2S,3S,5R)-1-(3,5-difluorophenoxy)-3-hydroxy-5-(2-methoxyethoxy)-6-[[(2S)-3-methyl-1-oxo-1-(phenylmethylamino)butan-2-yl]amino]-6-oxo-hexan-2-yl]-5-(methyl-methylsulfonyl-amino)-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide | n/a | |
| 330 | P56817_MY9 | MY9 | n/a | 16741230 | CHEMBL1234552 | N-{(1S,2S)-1-BENZYL-2-HYDROXY-2-[(4S)-1,2,2-TRIMETHYL-5-OXOIMIDAZOLIDIN-4-YL]ETHYL}-N'-[(1R)-1-(4-FLUOROPHENYL)ETHYL]-5-[METHYL(METHYLSULFONYL)AMINO]ISOPHTHALAMIDE | n/a | |
| 331 | P56817_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 332 | P56817_NI | NI | n/a | 934 | n/a | NICKEL (II) ION | n/a | |
| 333 | P56817_P6J | P6J | n/a | 118866105 | CHEMBL4560579 | N-{3-[(1S,5S,6S)-3-amino-1-(methoxymethyl)-5-methyl-2-thia-4-azabicyclo[4.1.0]hept-3-en-5-yl]-4,5-difluorophenyl}-5-[(prop-2-yn-1-yl)oxy]pyrazine-2-carboxamide | n/a | |
| 334 | P56817_P6U | P6U | n/a | 123132907 | CHEMBL4098403 | (4S)-4-[2,4-difluoro-5-({[1-(trifluoromethyl)cyclopropyl]amino}methyl)phenyl]-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine | n/a | |
| 335 | P56817_PB0 | PB0 | n/a | 11578322 | CHEMBL1915990 | (2S)-2-[(3R)-3-(acetylamino)-3-(2-methylpropyl)-2-oxopyrrolidin-1-yl]-N-{(1R,2S)-3-(3,5-difluorophenyl)-1-hydroxy-1-[(2R,4R)-4-propoxypyrrolidin-2-yl]propan-2-yl}-4-phenylbutanamide | n/a | |
| 336 | P56817_PB7 | PB7 | n/a | 53346502 | n/a | (2S)-2-{(3S)-3-(acetylamino)-3-[(2S)-butan-2-yl]-2-oxopyrrolidin-1-yl}-N-{(2S,3R)-3-hydroxy-4-[(3-methoxybenzyl)amino]-1-phenylbutan-2-yl}-4-phenylbutanamide | n/a | |
| 337 | P56817_PB8 | PB8 | n/a | 24997667 | CHEMBL1915985 | (2S)-2-[(3R)-3-(acetylamino)-3-(2-methylpropyl)-2-oxopyrrolidin-1-yl]-N-{(1R,2S)-3-(3,5-difluorophenyl)-1-hydroxy-1-[(3R)-1,2,3,4-tetrahydroisoquinolin-3-yl]propan-2-yl}-4-phenylbutanamide | n/a | |
| 338 | P56817_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 339 | P56817_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 340 | P56817_QBH | QBH | n/a | 50937466 | CHEMBL1615184 | (4S)-4-(2-hydroxy-5-{[(3S,4S,5R)-4-hydroxy-1,1-dioxido-5-{[3-(propan-2-yl)benzyl]amino}tetrahydro-2H-thiopyran-3-yl]methyl}benzyl)-3-propyl-1,3-oxazolidin-2-one | n/a | |
| 341 | P56817_QIN | QIN | n/a | 16741220 | n/a | N-[(1S,2S)-2-AMINO-1-(3-THIENYLMETHYL)HEXYL]-2-({[(1S,2S)-2-METHYLCYCLOPROPYL]METHYL}AMINO)-6-[METHYL(METHYLSULFONYL)AMINO]ISONICOTINAMIDE | n/a | |
| 342 | P56817_QJJ | QJJ | n/a | 145704715 | CHEMBL4637568 | N-{(1S,2S)-2-[(4aS,7aR)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]cyclopropyl}-5-fluoropyridine-2-carboxamide | n/a | |
| 343 | P56817_QJM | QJM | n/a | 145704716 | n/a | N-{(1R,2R)-2-[(4aS,7aR)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]cyclopropyl}-5-fluoropyridine-2-carboxamide | n/a | |
| 344 | P56817_QJP | QJP | n/a | 145704718 | CHEMBL4644249 | (1R,2R)-2-[(4aS,7aR)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-N-{[(1R,2R)-2-methylcyclopropyl]methyl}cyclopropane-1-carboxamide | n/a | |
| 345 | P56817_QJV | QJV | n/a | 145704717 | CHEMBL4642463 | (1R,2R)-2-[(4aS,7aR)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-N-butylcyclopropane-1-carboxamide | n/a | |
| 346 | P56817_QK7 | QK7 | n/a | 145704720 | CHEMBL4637426 | (4aR,7aR)-7a-[(1R,2R)-2-(2-{[(1R,2R)-2-methylcyclopropyl]methoxy}propan-2-yl)cyclopropyl]-6-(pyrimidin-2-yl)-4,4a,5,6,7,7a-hexahydropyrrolo[3,4-d][1,3]thiazin-2-amine | n/a | |
| 347 | P56817_QKA | QKA | n/a | 145704719 | CHEMBL4643727 | (1R,2R)-2-[(4aR,7aR)-2-amino-6-(pyrimidin-2-yl)-4a,5,6,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a(4H)-yl]-N-{[(1R,2R)-2-methylcyclopropyl]methyl}cyclopropane-1-carboxamide | n/a | |
| 348 | P56817_QN7 | QN7 | n/a | 90656184 | CHEMBL3260842 | (8S)-3,3-DIFLUORO-8-(2'-FLUORO-3'-METHOXYBIPHENYL-3-YL)-8-PYRIDIN-4-YL-2,3,4,8-TETRAHYDROIMIDAZO[1,5-A]PYRIMIDIN-6-AMINE | n/a | |
| 349 | P56817_QUD | QUD | n/a | 44631815 | n/a | 2-AMINO-3-{(1R)-1-CYCLOHEXYL-2-[(CYCLOHEXYLCARBONYL)AMINO]ETHYL}-6-PHENOXYQUINAZOLIN-3-IUM | n/a | |
| 350 | P56817_RSV | RSV | n/a | 53346492 | CHEMBL1821801 | 6-(thiophen-3-yl)quinolin-2-amine | n/a | |
| 351 | P56817_RTH | RTH | n/a | 53346493 | CHEMBL1821808 | 6-[2-(3,3-dimethylbut-1-yn-1-yl)phenyl]quinolin-2-amine | n/a | |
| 352 | P56817_RTM | RTM | n/a | 53346494 | CHEMBL1821809 | 3-(2-aminoquinolin-3-yl)-N-cyclohexyl-N-methylpropanamide | n/a | |
| 353 | P56817_RTN | RTN | n/a | 53236890 | CHEMBL1821811 | 3-[2-amino-6-(2-methylphenyl)quinolin-3-yl]-N-cyclohexylpropanamide | n/a | |
| 354 | P56817_RVI | RVI | n/a | 53346496 | n/a | (2R)-2-{[2-amino-6-(2-methylphenyl)quinolin-3-yl]methyl}-N-(cyclohexylmethyl)pentanamide | n/a | |
| 355 | P56817_S8Z | S8Z | n/a | 137349986 | n/a | (8R)-8-[4-(DIFLUOROMETHOXY)PHENYL]-3,3-DIFLUORO-8-[3-(3-METHOXYPROP-1-YN-1-YL)PHENYL]-2,3,4,8-TETRAHYDROIMIDAZO[1,5-A]PYRIMIDIN-6-AMINE | n/a | |
| 356 | P56817_SC6 | SC6 | n/a | 11578047 | CHEMBL403195 | N-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-2-[(2R,4R)-4-PHENOXYPYRROLIDIN-2-YL]ETHYL}-3-{[(2R)-2-(METHOXYMETHYL)PYRROLIDIN-1-YL]CARBONYL}-5-METHYLBENZAMIDE | n/a | |
| 357 | P56817_SC7 | SC7 | n/a | 11592145 | CHEMBL257278 | N'-{(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-[(2R,4S)-4-ETHOXYPIPERIDIN-2-YL]-2-HYDROXYETHYL}-5-METHYL-N,N-DIPROPYLISOPHTHALAMIDE | n/a | |
| 358 | P56817_SI5 | SI5 | n/a | 72547320 | CHEMBL3422238 | (4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-(1-methyl-1H-pyrazol-4-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine | n/a | |
| 359 | P56817_SII | SII | n/a | 25023930;135875806; | CHEMBL495087 | N-(4-{[4-(cyclohexylamino)-1-(3-fluorophenyl)-2-oxo-1,3,8-triazaspiro[4.5]dec-3-en-8-yl]methyl}phenyl)acetamide | n/a | |
| 360 | P56817_SKW | SKW | n/a | 155903124 | CHEMBL5093426 | ~{N}-[3-[(4~{S})-2-azanyl-4-methyl-5,6-dihydro-1,3-thiazin-4-yl]phenyl]-5-bromanyl-pyridine-2-carboxamide | n/a | |
| 361 | P56817_SL8 | SL8 | n/a | 50914981 | CHEMBL3653399 | ~{N}-[3-[(3~{R},6~{R})-5-azanyl-3,6-dimethyl-6-(trifluoromethyl)-2~{H}-1,4-oxazin-3-yl]phenyl]-5-bromanyl-pyridine-2-carboxamide | n/a | |
| 362 | P56817_SLK | SLK | n/a | 66665322 | CHEMBL3261067 | ~{N}-[3-[(3~{R},6~{R})-5-azanyl-3,6-dimethyl-6-(trifluoromethyl)-2~{H}-1,4-oxazin-3-yl]-4-fluoranyl-phenyl]-5-cyano-3-methyl-pyridine-2-carboxamide | n/a | |
| 363 | P56817_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 364 | P56817_TAR | TAR | DB01694 | 439655 | CHEMBL1200861 | D(-)-TARTARIC ACID | n/a | |
| 365 | P56817_TLA | TLA | DB09459 | 444305 | CHEMBL1236315 | L(+)-TARTARIC ACID | n/a | |
| 366 | P56817_U64 | U64 | n/a | 126557115 | CHEMBL4760458 | 6-[(Z)-2-{3-[(1S,5S,6S)-3-amino-5-methyl-1-(morpholine-4-carbonyl)-2-thia-4-azabicyclo[4.1.0]hept-3-en-5-yl]-4-fluorophenyl}-1-fluoroethenyl]pyridine-3-carbonitrile | n/a | |
| 367 | P56817_URE | URE | DB03904 | 1176 | CHEMBL985 | UREA | n/a | |
| 368 | P56817_VG0 | VG0 | n/a | 23657802 | CHEMBL252458 | N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(1,1,5-trimethylhexyl)amino]propyl}-3-(ethylamino)-5-(2-oxopyrrolidin-1-yl)benzamide | n/a | |
| 369 | P56817_VG3 | VG3 | n/a | 23657804 | CHEMBL402305 | N-[(1S,2R)-1-benzyl-3-{[(1S)-2-(cyclohexylamino)-1-methyl-2-oxoethyl]amino}-2-hydroxypropyl]-3-(pentylsulfonyl)benzamide | n/a | |
| 370 | P56817_VG4 | VG4 | n/a | 49867818 | n/a | N-[(1S,2R)-1-benzyl-3-{[(1S)-2-(cyclohexylamino)-1-methyl-2-oxoethyl]amino}-2-hydroxypropyl]-3-(2-oxo-2,3-dihydro-1H-pyrrol-1-yl)-5-propoxybenzamide | n/a | |
| 371 | P56817_VG5 | VG5 | n/a | 24882338 | CHEMBL251862 | N-[(1S,2R)-1-benzyl-3-{[(1S)-2-(cyclohexylamino)-1-methyl-2-oxoethyl]amino}-2-hydroxypropyl]-3-(ethylamino)-5-(2-oxopyrrolidin-1-yl)benzamide | n/a | |
| 372 | P56817_VG6 | VG6 | n/a | 10008157 | CHEMBL403429 | N-[(1S,2R)-1-benzyl-2-hydroxy-3-{[3-(trifluoromethyl)benzyl]amino}propyl]-3-(ethylamino)-5-(2-oxopyrrolidin-1-yl)benzamide | n/a | |
| 373 | P56817_VG7 | VG7 | n/a | 9983140 | CHEMBL252057 | N-[(1S,2R)-1-benzyl-3-(cyclohexylamino)-2-hydroxypropyl]-3-(ethylamino)-5-(2-oxopyrrolidin-1-yl)benzamide | n/a | |
| 374 | P56817_VSI | VSI | n/a | 71777705 | CHEMBL5270666 | N-{N-[4-(acetylamino)-3,5-dichlorobenzyl]carbamimidoyl}-2-(6-cyano-1H-indol-1-yl)acetamide | n/a | |
| 375 | P56817_VTI | VTI | n/a | 71777706 | n/a | N-{N-[4-(acetylamino)-3,5-dichlorobenzyl]carbamimidoyl}-2-(1H-indol-1-yl)acetamide | n/a | |
| 376 | P56817_WM9 | WM9 | n/a | 71576786 | n/a | (2S)-2-[3-(3-chlorophenyl)phenyl]-2-methyl-5,6-dihydro-1,3-oxazin-4-amine | n/a | |
| 377 | P56817_WZV | WZV | n/a | 49819211 | n/a | 5-(2,2,2-Trifluoro-ethoxy)-pyridine-2-carboxylic acid [3-((S)-2-amino-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-4-yl)-phenyl]-amide | n/a | |
| 378 | P56817_X17 | X17 | n/a | n/a | n/a | (5S)-2-amino-5-(4-methoxy-3-methylphenyl)-3-methyl-5-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]-3,5-dihydro-4H-imidazol-4-one | n/a | |
| 379 | P56817_X45 | X45 | n/a | 49867832 | CHEMBL1236759 | (5S)-2-amino-5-(4-methoxy-3-methylphenyl)-3-methyl-5-(3-pyridin-3-ylphenyl)-3,5-dihydro-4H-imidazol-4-one | n/a | |
| 380 | P56817_XFI | XFI | n/a | 10416248 | CHEMBL1210329 | N-((1S,2R)-3-(((1S)-2-(CYCLOHEXYLAMINO)-1-METHYL-2-OXOETHYL)AMINO)-2-HYDROXY-1-( PHENYLMETHYL)PROPYL)-3-((METHYLSULFONYL)(PHENYL)AMINO) BENZAMIDE | n/a | |
| 381 | P56817_XK0 | XK0 | n/a | 71571522 | n/a | (4S)-4-(4-methoxyphenyl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine | n/a | |
| 382 | P56817_XLI | XLI | n/a | 45259043 | CHEMBL1097361 | N-acetyl-L-leucyl-N-[(4S,5S,7R)-8-(butylamino)-5-hydroxy-2,7-dimethyl-8-oxooctan-4-yl]-L-methioninamide | n/a | |
| 383 | P56817_XX4 | XX4 | DB08749 | 16741238 | CHEMBL244342 | 3-(2-AMINO-6-BENZOYLQUINAZOLIN-3(4H)-YL)-N-CYCLOHEXYL-N-METHYLPROPANAMIDE | n/a | Ki(nM) = 900.0 |
| 384 | P56817_Z74 | Z74 | n/a | 45105273 | CHEMBL1097319 | N'-{(1S,2S)-1-(3,5-difluorobenzyl)-2-hydroxy-2-[(2R)-4-(phenylsulfonyl)piperazin-2-yl]ethyl}-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | n/a | |
| 385 | P56817_Z75 | Z75 | n/a | 11707063 | CHEMBL1097356 | N'-[(1S,2S)-2-[(2R)-4-benzylpiperazin-2-yl]-1-(3,5-difluorobenzyl)-2-hydroxyethyl]-5-methyl-N,N-dipropylbenzene-1,3-dicarboxamide | n/a | |
| 386 | P56817_Z76 | Z76 | n/a | 45105274 | CHEMBL1097342 | N-[(1S,2S)-1-(3,5-difluorobenzyl)-2-hydroxy-2-{(2R)-4-[(3-methylphenyl)sulfonyl]piperazin-2-yl}ethyl]-3-{[(2R)-2-(methoxymethyl)pyrrolidin-1-yl]carbonyl}-5-methylbenzamide | n/a | |
| 387 | P56817_Z81 | Z81 | n/a | 46830239 | CHEMBL1092788 | (5S)-2-amino-5-(2',5'-difluorobiphenyl-3-yl)-3-methyl-5-pyridin-4-yl-3,5-dihydro-4H-imidazol-4-one | n/a | |
| 388 | P56817_ZN | ZN | n/a | 32051 | CHEMBL1236970 | ZINC ION | n/a | |
| 389 | P56817_ZOO | ZOO | n/a | 52948140 | CHEMBL1270835 | (5R)-2-amino-5-[4-(difluoromethoxy)phenyl]-5-[4-fluoro-3-(5-fluoropent-1-yn-1-yl)phenyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one | n/a | |
| 390 | P56817_ZPQ | ZPQ | n/a | 6540293 | CHEMBL448008 | N~2~-[(2R,4S,5S)-5-{[N-{[(3,5-DIMETHYL-1H-PYRAZOL-1-YL)METHOXY]CARBONYL}-3-(METHYLSULFONYL)-L-ALANYL]AMINO}-4-HYDROXY-2,7-DIMETHYLOCTANOYL]-N-ISOBUTYL-L-VALINAMIDE | n/a | |
| 391 | P56817_ZPX | ZPX | n/a | 66575070 | n/a | N-[(1R)-1-(4-fluorophenyl)ethyl]-N'-[(2S,3S)-3-hydroxy-1-phenyl-4-(1H-pyrazol-1-yl)butan-2-yl]-5-[methyl(methylsulfonyl)amino]benzene-1,3-dicarboxamide | n/a | |
| 392 | P56817_ZPY | ZPY | n/a | 66575071 | n/a | ethyl 1-{(2S,3S)-3-[(3-{[(1R)-1-(4-fluorophenyl)ethyl]carbamoyl}-5-[methyl(methylsulfonyl)amino]benzoyl)amino]-2-hydroxy-4-phenylbutyl}-1H-pyrazole-4-carboxylate | n/a | |
| 393 | P56817_ZPZ | ZPZ | n/a | 66575072 | n/a | N-[(1R)-1-(4-fluorophenyl)ethyl]-N'-[(2S,3S)-3-hydroxy-4-{4-[(1S)-1-hydroxyethyl]-1H-1,2,3-triazol-1-yl}-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]benzene-1,3-dicarboxamide | n/a | |
| 394 | P56817_ZQS | ZQS | n/a | 78318700 | CHEMBL5095827 | (4aR,7aR)-6-(pyrimidin-2-yl)-7a-(thiophen-2-yl)-4,4a,5,6,7,7a-hexahydropyrrolo[3,4-d][1,3]thiazin-2-amine | n/a | |
| 395 | P56817_ZR7 | ZR7 | n/a | 78210254 | CHEMBL4452566 | N-{3-[(4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4a,5,6,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a(4H)-yl]-4-fluorophenyl}-5-methoxypyrazine-2-carboxamide | n/a | |
| 396 | P56817_ZRD | ZRD | n/a | 71738999 | CHEMBL3704998 | (4aR,7aR)-6-(5-fluoropyrimidin-2-yl)-7a-(1,2-thiazol-5-yl)-4,4a,5,6,7,7a-hexahydropyrrolo[3,4-d][1,3]thiazin-2-amine | n/a | |
| 397 | P56817_ZY0 | ZY0 | n/a | 44143269 | CHEMBL501958 | N-[(1S,2R)-1-BENZYL-2-HYDROXY-3-{[3-(TRIFLUOROMETHYL)BENZYL]AMINO}PROPYL]-4-ETHYL-8-(2-OXOPYRROLIDIN-1-YL)QUINOLINE-6-CARBOXAMIDE | n/a | |
| 398 | P56817_ZY1 | ZY1 | n/a | 9938431 | CHEMBL539436 | N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}-7-ethyl-1-methyl-3,4-dihydro-1H-[1,2,5]thiadiazepino[3,4,5-hi]indole-9-carboxamide 2,2-dioxide | n/a | |
| 399 | P56817_ZY2 | ZY2 | n/a | 49867919 | n/a | N-{(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-8-ETHYL-1-METHYL-3,4,7,8-TETRAHYDRO-1H,6H-[1,2,5]THIADIAZEPINO[5,4,3-DE]QUINOXALINE-10-CARBOXAMIDE 2,2-DIOXIDE | n/a | |
| 400 | P56817_ZY3 | ZY3 | n/a | 25271562 | n/a | N-{(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-6-(ETHYLAMINO)-1-METHYL-1,3,4,5-TETRAHYDRO-2,1-BENZOTHIAZEPINE-8-CARBOXAMIDE 2,2-DIOXIDE | n/a | |
| 401 | P56817_ZY4 | ZY4 | n/a | 49867920 | n/a | N-[(1S)-1-BENZYL-2,2-DIHYDROXY-3-(TETRAHYDRO-2H-PYRAN-4-YLAMINO)PROPYL]-6-ETHYL-1-METHYL-1,3,4,6-TETRAHYDRO[1,2]THIAZEPINO[5,4,3-CD]INDOLE-8-CARBOXAMIDE 2,2-DIOXIDE | n/a | |
| 402 | P56817_ZYE | ZYE | n/a | 44526776 | CHEMBL529838 | N-{(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}-1-ETHYL-4-(2-OXOPYRROLIDIN-1-YL)-1H-INDOLE-6-CARBOXAMIDE | n/a |