Gene name: ERBB4
Protein name: Receptor tyrosine-protein kinase
List of molecules and drugs that interact with protein Q15303
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q15303_FMM | FMM | DB01259 | 208908 | CHEMBL554 | N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE | n/a | IC50(nM) = 7.6 Kd(nM) = 54.0 |
| 2 | Q15303_GW7 | GW7 | n/a | 49867063 | n/a | N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amine | n/a | |
| 3 | Q15303_MN | MN | n/a | 27854 | n/a | MANGANESE (II) ION | n/a | |
| 4 | Q15303_NAG | NAG | DB00141 | 24139 | CHEMBL447878 | 2-acetamido-2-deoxy-beta-D-glucopyranose | n/a | |
| 5 | Q15303_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 6 | Q15303_PG4 | PG4 | n/a | 8200 | CHEMBL1235254 | TETRAETHYLENE GLYCOL | n/a | |
| 7 | Q15303_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 8 | Q15303_YT3 | YT3 | n/a | 168049 | n/a | YTTRIUM (III) ION | n/a | |
| 9 | Q15303_0WM | 0WM | DB08916 | 10184653 | CHEMBL1173655 | Afatinib | inhibitor | IC50(nM) = 1.0 Kd(nM) = 6.3 |
| 10 | Q15303_2RC | 2RC | DB12010 | 11671467 | CHEMBL2103830 | Fostamatinib | inhibitor | |
| 11 | Q15303_6GY | 6GY | DB12267 | 68165256 | CHEMBL3545311 | Brigatinib | inhibitor | |
| 12 | Q15303_DB15035 | n/a | DB15035 | n/a | n/a | Zanubrutinib | inhibitor |