Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Q16539 MK14_HUMAN
Gene name: MAPK14
Protein name: Mitogen-activated protein kinase

List of molecules and drugs that interact with protein Q16539

# DrugDomain Data PBD ligand DrugBank Accession PubChem ChEMBL Name Drug action Affinity data
1 Q16539_048 048 n/a 66557865 CHEMBL2177219 N-{2-fluoro-5-[(5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino]phenyl}benzamide n/a
2 Q16539_06F 06F n/a 70679347 CHEMBL5178950 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-{3-[(5-oxo-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino]phenyl}urea n/a
3 Q16539_084 084 DB01761 447721 CHEMBL305178 4-[5-[2-(1-PHENYL-ETHYLAMINO)-PYRIMIDIN-4-YL]-1-METHYL-4-(3-TRIFLUOROMETHYLPHENYL)-1H-IMIDAZOL-2-YL]-PIPERIDINE n/a IC50(nM) = 0.11
4 Q16539_094 094 n/a 5287409 n/a 1-(2,6-DICHLOROPHENYL)-6-[(2,4-DIFLUOROPHENYL)SULFANYL]-7-(1,2,3,6-TETRAHYDRO-4-PYRIDINYL)-3,4-DIHYDROPYRIDO[3,2-D]PYRIMIDIN-2(1H)-ONE n/a
5 Q16539_09J 09J n/a 56951457 CHEMBL1945723 3-[3-(2-chloro-6-fluorophenyl)-5-ethyl-6-oxo-5,6-dihydro[1,2,4]triazolo[4,3-b]pyridazin-7-yl]-N-cyclopropyl-4-methylbenzamide n/a
6 Q16539_0O8 0O8 n/a 148178 n/a (1,1-dimethylpiperidin-1-ium-4-yl) octadecyl hydrogen phosphate n/a
7 Q16539_0O9 0O9 n/a 137347876 n/a (2S)-2-methoxy-3-(octadecyloxy)propyl (1R,2R,3R,4S,6S)-2,3,4-trihydroxy-6-(2-methylpropoxy)cyclohexyl hydrogen (S)-phosphate n/a
8 Q16539_0OA 0OA n/a 137347877 n/a (1R,2S,3R,4S,6S)-6-(cyclohexylmethoxy)-2,3,4-trihydroxycyclohexyl (2R)-2-methoxy-3-(octadecyloxy)propyl hydrogen (S)-phosphate n/a
9 Q16539_0OK 0OK n/a 785275 CHEMBL5440525 3-phenylquinazolin-4(3H)-one n/a
10 Q16539_0OL 0OL n/a 69892 CHEMBL1897277 phenyl(piperidin-1-yl)methanone n/a
11 Q16539_0OM 0OM DB15764 7191 CHEMBL209744 benzyl pyridine-3-carboxylate n/a
12 Q16539_0ON 0ON n/a 74463 CHEMBL454533 N-phenylpyridine-3-carboxamide n/a
13 Q16539_0OO 0OO n/a 26295 CHEMBL1869836 (3-phenoxyphenyl)methanol n/a
14 Q16539_0OP 0OP n/a 74341 n/a [3-(benzyloxy)phenyl]methanol n/a
15 Q16539_0OQ 0OQ n/a 66563668 n/a (1R,5S)-3-[4-(trifluoromethyl)benzoyl]-1,2,3,4,5,6-hexahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one n/a
16 Q16539_0SJ 0SJ n/a 42365204 n/a (1R,5S)-3-(4-chlorobenzoyl)-1,2,3,4,5,6-hexahydro-8H-1,5-methanopyrido[1,2-a][1,5]diazocin-8-one n/a
17 Q16539_19B 19B n/a 9983303 CHEMBL485285 4-methyl-N-(3-morpholin-4-ylphenyl)-3-(3-piperidin-4-yl-1,2-benzisoxazol-6-yl)benzamide n/a
18 Q16539_1AU 1AU DB06882 25174101 CHEMBL522387 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea n/a IC50(nM) = 90.0
Kd(nM) = 12.0
19 Q16539_1BU 1BU n/a 42601396 CHEMBL497033 1-{4-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1H-pyrazol-5-yl]urea n/a
20 Q16539_1GK 1GK n/a 1489193 CHEMBL1171204 N-(furan-2-ylmethyl)-4-[(2-methylphenyl)carbonyl]-1H-pyrrole-2-carboxamide n/a
21 Q16539_1M8 1M8 n/a 24985573 CHEMBL2401983 5-(2-chlorophenyl)-N-[5-(cyclopropylcarbamoyl)-2-methylphenyl]thiophene-2-carboxamide n/a
22 Q16539_1N1 1N1 DB01254 3062316 CHEMBL1421 N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE binder IC50(nM) = 100.0
Kd(nM) = 27.0
EC50(nM) = 470.0
23 Q16539_1PP 1PP n/a 5327064 CHEMBL63071 1-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-3-(2,3-dichlorophenyl)urea n/a
24 Q16539_1R9 1R9 n/a 49326850 CHEMBL2401978 2-(2-chlorophenyl)-N-[5-(cyclopropylcarbamoyl)-2-methylphenyl]-1,3-thiazole-5-carboxamide n/a
25 Q16539_1RA 1RA n/a 58328161 CHEMBL2402005 ethyl 6-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]carbamoyl}-1H-indole-1-carboxylate n/a
26 Q16539_1VI 1VI n/a 126456393 n/a 3-(2,5-dimethoxyphenyl)-~{N}-[4-[4-(4-fluorophenyl)-2-methylsulfanyl-1~{H}-imidazol-5-yl]pyridin-2-yl]propanamide n/a
27 Q16539_222 222 n/a 11957412 CHEMBL221595 2-(3-{(2-CHLORO-4-FLUOROPHENYL)[1-(2-CHLOROPHENYL)-6-OXO-1,6-DIHYDROPYRIDAZIN-3-YL]AMINO}PROPYL)-1H-ISOINDOLE-1,3(2H)-DIONE n/a
28 Q16539_279 279 DB06940 10134493 CHEMBL252128 N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide n/a IC50(nM) = 3.1
EC50(nM) = 61.0
29 Q16539_287 287 n/a 10276213 CHEMBL252535 4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methyl-N-[(1S)-1-phenylethyl]pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide n/a
30 Q16539_29A 29A n/a 11683817 CHEMBL1738710 3-{5-chloro-4-[(2,4-difluorobenzyl)oxy]-6-oxopyrimidin-1(6H)-yl}-N-(2-hydroxyethyl)-4-methylbenzamide n/a
31 Q16539_29B 29B n/a 15428657 n/a 4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine n/a
32 Q16539_2A8 2A8 n/a 11955788 CHEMBL218962 2-AMINO-PHENYLAMINO-DIBENZOSUBERONE n/a
33 Q16539_2CH 2CH DB03110 7245 CHEMBL108877 2-CHLOROPHENOL inhibitor
34 Q16539_304 304 DB06991 11427975 CHEMBL258202 N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide n/a IC50(nM) = 3.5
35 Q16539_337 337 n/a 10257839 n/a N-benzyl-1-[5-({5-tert-butyl-2-methoxy-3-[(methylsulfonyl)amino]phenyl}carbamoyl)-2-methylphenyl]-1H-1,2,3-triazole-4-carboxamide n/a
36 Q16539_358 358 DB01948 447725 CHEMBL564912 1-(2,6-DICHLOROPHENYL)-5-(2,4-DIFLUOROPHENYL)-7-PIPERIDIN-4-YL-3,4-DIHYDROQUINOLIN-2(1H)-ONE n/a IC50(nM) = 0.74
37 Q16539_38P 38P DB12696 10409068 CHEMBL1230065 4-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]amino}-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide n/a
38 Q16539_39G 39G n/a 2812918 CHEMBL3393296 N-[5-(dimethylsulfamoyl)-2-methylphenyl]-1-phenyl-5-propyl-1H-pyrazole-4-carboxamide n/a
39 Q16539_39P 39P n/a 10002975 CHEMBL1230070 4-{[5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl]amino}-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide n/a
40 Q16539_3FF 3FF n/a 45279963 CHEMBL2152944 2-[(2,4-difluorophenyl)amino]-7-{[(2R)-2,3-dihydroxypropyl]oxy}-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-one n/a
41 Q16539_3FN 3FN DB06518 11406590 CHEMBL1230122 6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one inhibitor
42 Q16539_3GF 3GF n/a 86270361 CHEMBL4129018 6-(4-methylpiperazin-1-yl)-3-(naphthalen-2-yl)-4-(pyridin-4-yl)pyridazine n/a
43 Q16539_3IP 3IP DB02352 90334 CHEMBL194009 3-(BENZYLOXY)PYRIDIN-2-AMINE inhibitor IC50(nM) = 100000.0
44 Q16539_3NE 3NE n/a 49766627;135566520; CHEMBL1230164 4-(trifluoromethyl)-3-[3-(trifluoromethyl)phenyl]-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one n/a
45 Q16539_3NW 3NW n/a 46864262 CHEMBL1230171 1-[2-(2-{[2-(dimethylamino)ethyl]amino}-6-{2-[(1-methylethyl)amino]-1,3-thiazol-5-yl}pyrimidin-4-yl)benzyl]-3-ethylurea n/a
46 Q16539_437 437 n/a 46870032 CHEMBL1271167 1-{3-tert-butyl-1-[4-(hydroxymethyl)phenyl]-1H-pyrazol-5-yl}-3-naphthalen-1-ylurea n/a
47 Q16539_469 469 DB05412 9871074 CHEMBL514201 2-(6-chloro-5-{[(2R,5S)-4-(4-fluorobenzyl)-2,5-dimethylpiperazin-1-yl]carbonyl}-1-methyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide modulator
48 Q16539_52P 52P DB07138 3038525 CHEMBL119385 5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-b]pyridazin-6-one inhibitor Ki(nM) = 0.8
IC50(nM) = 9.0
Kd(nM) = 2.8
49 Q16539_530 530 n/a 44517636 CHEMBL1230350 6-(2,4-difluorophenoxy)-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-amine n/a
50 Q16539_533 533 n/a 44517632 CHEMBL1230351 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1R)-1-methyl-2-(2H-tetrazol-2-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one n/a
51 Q16539_5JZ 5JZ n/a 42640803 CHEMBL1213155 N~2~-{4-[6-(3,4-dihydroquinolin-1(2H)-ylcarbonyl)-1H-benzimidazol-1-yl]-6-ethoxy-1,3,5-triazin-2-yl}-3-(2,2-dimethyl-4H-1,3-benzodioxin-6-yl)-N-methyl-L-alaninamide n/a
52 Q16539_6NP 6NP DB01988 4369379 n/a 6((S)-3-BENZYLPIPERAZIN-1-YL)-3-(NAPHTHALEN-2-YL)-4-(PYRIDIN-4-YL)PYRAZINE n/a
53 Q16539_6RG 6RG n/a 70680566 n/a 2-phenyl-N~4~-(2-phenylethyl)quinazoline-4,7-diamine n/a
54 Q16539_78L 78L n/a 137348574 CHEMBL4061315 ~{N}-[2,4-bis(fluoranyl)-5-[[9-(2-morpholin-4-ylethylcarbamoyl)-11-oxidanylidene-5,6-dihydrodibenzo[1,2-~{d}:1',2'-~{f}][7]annulen-3-yl]amino]phenyl]thiophene-2-carboxamide n/a
55 Q16539_79Q 79Q n/a 71545859 CHEMBL2316207 3-[(3-benzamido-4-fluoranyl-phenyl)amino]-~{N}-(2-morpholin-4-ylethyl)-11-oxidanylidene-5,6-dihydrodibenzo[1,2-~{d}:1',2'-~{f}][7]annulene-9-carboxamide n/a
56 Q16539_891 891 n/a 44517629 CHEMBL1230610 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1S)-1-methyl-2-(methylsulfonyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one n/a
57 Q16539_8EN 8EN n/a 56929808 CHEMBL4216073 ~{N}-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methyl-phenyl]-3-(trifluoromethyl)benzamide n/a
58 Q16539_8OH 8OH n/a 129900315 n/a 2-phenyl-~{N}4-(thiophen-2-ylmethyl)quinazoline-4,7-diamine n/a
59 Q16539_8OK 8OK n/a 129900319 n/a 2-(4-morpholin-4-ylphenyl)-~{N}4-(2-phenylethyl)quinazoline-4,7-diamine n/a
60 Q16539_8ON 8ON n/a 129900318 n/a 1-[4-[4-[7-azanyl-4-(2-phenylethylamino)quinazolin-2-yl]phenyl]piperazin-1-yl]ethanone n/a
61 Q16539_8OT 8OT n/a 129900316 n/a 2-phenyl-~{N}4-(2-thiophen-2-ylethyl)quinazoline-4,7-diamine n/a
62 Q16539_8OW 8OW n/a 129900314 n/a ~{N}4-[(4-fluorophenyl)methyl]-2-phenyl-quinazoline-4,7-diamine n/a
63 Q16539_9O2 9O2 n/a 137348842 n/a ~{N}-[3-[7-azanyl-4-(2-phenylethylamino)quinazolin-2-yl]phenyl]propanamide n/a
64 Q16539_9O5 9O5 n/a 137348844 n/a 4-[3-[7-azanyl-4-(2-phenylethylamino)quinazolin-2-yl]phenyl]butan-2-one n/a
65 Q16539_9Y5 9Y5 n/a 137530066 n/a 1-(3-chlorophenyl)-3-methyl-4~{H}-pyrazolo[4,3-c][1,2]benzothiazine 5,5-dioxide n/a
66 Q16539_9Y8 9Y8 n/a 138753124 n/a 3-(4-fluorophenyl)-4-methyl-1~{H}-pyrazolo[4,3-c][1,2]benzothiazine 5,5-dioxide n/a
67 Q16539_A17 A17 DB07307 24941253 CHEMBL492265 N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide n/a Ki(nM) = 0.4
IC50(nM) = 0.8
68 Q16539_AA0 AA0 n/a 22238181 CHEMBL2031219 N-[4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxidanylidene-quinazolin-3-yl]phenyl]-2-morpholin-4-yl-pyridine-4-carboxamide n/a
69 Q16539_AAV AAV n/a 11554076 CHEMBL2031461 N-isoxazol-3-yl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxo-quinazolin-3-yl]benzamide n/a
70 Q16539_ACT ACT DB14511 175 n/a ACETATE ION n/a
71 Q16539_AP2 AP2 DB03148 92199 CHEMBL583969 PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER n/a
72 Q16539_AQY AQY n/a 137348940 CHEMBL4224940 N-{4-[2-(4-fluoro-3-methylphenyl)imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl}-2-methyl-1-oxo-1lambda~5~-pyridine-4-carboxamide n/a
73 Q16539_AQZ AQZ n/a 5327065 CHEMBL184659 N-(3-{[7-METHOXY-6-(2-PYRROLIDIN-1-YLETHOXY)QUINAZOLIN-4-YL]AMINO}-4-METHYLPHENYL)-2-MORPHOLIN-4-YLISONICOTINAMIDE n/a
74 Q16539_B10 B10 n/a 9917045 CHEMBL451523 N-{5-tert-butyl-2-methoxy-3-[({4-[6-(morpholin-4-ylmethyl)pyridin-3-yl]naphthalen-1-yl}carbamoyl)amino]phenyl}methanesulfonamide n/a
75 Q16539_B11 B11 DB04632 5287728 CHEMBL197277 N-[3-(4-FLUOROPHENOXY)PHENYL]-4-[(2-HYDROXYBENZYL)AMINO]PIPERIDINE-1-SULFONAMIDE n/a IC50(nM) = 6000.0
76 Q16539_B45 B45 n/a 23532664 CHEMBL328242 5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-[1-(1-methylethyl)piperidin-4-yl]-3,4-dihydroquinazolin-2(1H)-one n/a
77 Q16539_B96 B96 DB03044 156422 CHEMBL103667 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA n/a Ki(nM) = 0.1
IC50(nM) = 0.1
Kd(nM) = 0.098
kon(M-1-s-1) = 84900.0
koff(s-1) = 8.0E-6
78 Q16539_BAX BAX DB00398 216239 CHEMBL1336 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE n/a IC50(nM) = 37.0
Kd(nM) = 260.0
79 Q16539_BFF BFF DB12962 9811611 CHEMBL253969 3-[(4-bromo-2,6-difluorobenzyl)oxy]-5-{[(4-pyrrolidin-1-ylbutyl)carbamoyl]amino}isothiazole-4-carboxamide n/a
80 Q16539_BI5 BI5 DB07459 2352168 CHEMBL199237 4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE inhibitor IC50(nM) = 1500.0
81 Q16539_BME BME DB03345 1567 CHEMBL254951 BETA-MERCAPTOETHANOL n/a
82 Q16539_BMU BMU DB02277 446816 CHEMBL87277 1-(5-TERT-BUTYL-2-METHYL-2H-PYRAZOL-3-YL)-3-(4-CHLORO-PHENYL)-UREA n/a IC50(nM) = 794.0
Kd(nM) = 1160.0
kon(M-1-s-1) = 118000.0
koff(s-1) = 0.14
83 Q16539_BOG BOG n/a 62852 CHEMBL446037 octyl beta-D-glucopyranoside n/a
84 Q16539_BW1 BW1 n/a 129900317 n/a ~{N}4-[[4-(cyclopropylmethyl)furan-2-yl]methyl]-2-phenyl-quinazoline-4,7-diamine n/a
85 Q16539_CL CL n/a 312 n/a CHLORIDE ION n/a
86 Q16539_CQ0 CQ0 n/a 25059320 CHEMBL2087500 3-(3-tert-butyl[1,2,4]triazolo[4,3-a]pyridin-7-yl)-N-cyclopropyl-4-methylbenzamide n/a
87 Q16539_D13 D13 DB07607 9543437 n/a 4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE n/a
88 Q16539_DF3 DF3 n/a 4405380 CHEMBL1232179 N-[2-(3-{[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]sulfanyl}-1H-indol-1-yl)ethyl]-3-(trifluoromethyl)benzamide n/a
89 Q16539_DG7 DG7 n/a 53470402 CHEMBL1940501 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-{4-[2-(pyridin-3-ylmethoxy)ethyl]-1,3-thiazol-2-yl}urea n/a
90 Q16539_DMS DMS DB01093 679 CHEMBL504 DIMETHYL SULFOXIDE n/a
91 Q16539_DQO DQO DB02873 4630909 CHEMBL94417 1-(2,6-DICHLOROPHENYL)-5-(2,4-DIFLUOROPHENYL)-7-PIPERAZIN-1-YL-3,4-DIHYDROQUINAZOLIN-2(1H)-ONE n/a IC50(nM) = 2.6
92 Q16539_EDB EDB n/a n/a n/a 2-{3-[(5E)-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-3-thiophen-2-yl-2,5-dihydro-1H-pyrazol-1-yl]phenyl}acetamide n/a
93 Q16539_EDD EDD n/a n/a n/a 2-[3-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]imino}-2,5-dihydro-1H-pyrazol-1-yl)phenyl]acetamide n/a
94 Q16539_EDO EDO n/a 174 CHEMBL457299 1,2-ETHANEDIOL n/a
95 Q16539_EPE EPE DB16872 23830;23831;3275884; CHEMBL1232545 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID n/a
96 Q16539_F46 F46 n/a 71748684 CHEMBL3086685 N-[2-fluoro-5-({9-[2-(morpholin-4-yl)ethoxy]-11-oxo-6,11-dihydrodibenzo[b,e]oxepin-3-yl}amino)phenyl]benzamide n/a
97 Q16539_F4C F4C n/a 44251520 CHEMBL1232634 2-(4-fluorophenyl)-3-oxo-6-pyridin-4-yl-N-[2-(trifluoromethyl)benzyl]-2,3-dihydropyridazine-4-carboxamide n/a
98 Q16539_FI4 FI4 n/a 11373838 n/a (2S)-1-{[3-(2-chlorophenyl)-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino}propan-2-ol n/a
99 Q16539_FJI FJI n/a 129900105 CHEMBL4095093 3-[(3-benzamido-4-fluoranyl-phenyl)amino]-~{N}-(2-morpholin-4-ylethyl)-11-oxidanylidene-6~{H}-benzo[c][1]benzoxepine-9-carboxamide n/a
100 Q16539_FKL FKL n/a 25016226 CHEMBL1232751 N-cyclopropyl-4-methyl-3-[8-methyl-7-oxo-2-(tetrahydro-2H-pyran-4-ylamino)-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl]benzamide n/a
101 Q16539_FKN FKN n/a 16045647 n/a 3-[2-chloro-5-(methylsulfonyl)phenyl]-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidine n/a
102 Q16539_FKO FKO n/a 11772121 n/a 3-(2-chlorophenyl)-6-(2-fluorophenoxy)-2H-indazole n/a
103 Q16539_FL4 FL4 n/a 44517628 n/a 6-(2,4-difluorophenoxy)-3-(2-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidine n/a
104 Q16539_FLS FLS n/a 44517630 CHEMBL1232769 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1R)-1-methyl-2-(methylsulfonyl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one n/a
105 Q16539_FLW FLW DB19169 16220188 CHEMBL1090089 6-(2,4-difluorophenoxy)-2-{[3-hydroxy-1-(2-hydroxyethyl)propyl]amino}-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one inhibitor
106 Q16539_FLY FLY n/a 44517631 CHEMBL1232772 6-(2,4-difluorophenoxy)-8-methyl-2-[(1-methylethyl)amino]pyrido[2,3-d]pyrimidin-7(8H)-one n/a
107 Q16539_FLZ FLZ n/a 23434577 CHEMBL1232773 8-methyl-6-phenoxy-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one n/a
108 Q16539_FMJ FMJ n/a 2745721 CHEMBL1232783 4-(5-methyl-3-phenylisoxazol-4-yl)pyrimidin-2-amine n/a
109 Q16539_FMK FMK n/a 44517633 CHEMBL1232784 6-(2,4-difluorophenoxy)-8-methyl-2-{[(1S)-1-methyl-2-(2H-tetrazol-2-yl)ethyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one n/a
110 Q16539_FML FML n/a 44517634 CHEMBL1232785 6-(2,4-difluorophenoxy)-N-[(1S)-1-methyl-2-(methylsulfonyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-3-amine n/a
111 Q16539_FPH FPH DB02195 5288238 n/a 3-(4-FLUOROPHENYL)-2-PYRIDIN-4-YL-1H-PYRROLO[3,2-B]PYRIDIN-1-OL n/a
112 Q16539_FS8 FS8 n/a 70678406 CHEMBL4575052 N-{5-[(7-{[(2R)-2,3-dihydroxypropyl]oxy}-5-oxo-10,11-dihydro-5H-dibenzo[a,d][7]annulen-2-yl)amino]-2-fluorophenyl}benzamide n/a
113 Q16539_FSS FSS n/a 49867002 n/a 3-(2,6-dichlorophenyl)-7-({4-[(diethylamino)methoxy]phenyl}amino)-1-methyl-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one n/a
114 Q16539_FTZ FTZ n/a 16015442 CHEMBL1354522 N-(2-chloro-6-fluorobenzyl)-5-(furan-2-yl)-2H-1,2,4-triazol-3-amine n/a
115 Q16539_G11 G11 n/a 21914519 CHEMBL1232887 6-[5-(cyclopropylcarbamoyl)-2-methylphenyl]-N-(cyclopropylmethyl)pyridine-3-carboxamide n/a
116 Q16539_G6A G6A DB07811 10089048 CHEMBL522579 N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide n/a Ki(nM) = 10.0
117 Q16539_G97 G97 n/a 49867019 CHEMBL1232944 N-[2-phenyl-4-(1H-pyrazol-3-ylamino)quinazolin-7-yl]prop-2-enamide n/a
118 Q16539_GE5 GE5 n/a n/a n/a 3-(2,5-dimethoxyphenyl)-~{N}-[4-[4-(4-fluorophenyl)-2-[(~{E})-phenyldiazenyl]-1,3-thiazol-5-yl]pyridin-2-yl]propanamide n/a
119 Q16539_GEW GEW n/a n/a n/a 3-(2,5-dimethoxyphenyl)-~{N}-[4-[5-(4-fluorophenyl)-2-[(~{E})-(4-fluorophenyl)diazenyl]-3-methyl-imidazol-4-yl]pyridin-2-yl]propanamide n/a
120 Q16539_GG5 GG5 DB07829 12106168 CHEMBL1233024 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE inhibitor Ki(nM) = 600.0
IC50(nM) = 67.0
121 Q16539_GK1 GK1 DB07832 23644582 CHEMBL237127 4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde n/a Ki(nM) = 400.0
IC50(nM) = 2500.0
122 Q16539_GK3 GK3 DB07833 10200651 CHEMBL270164 N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide n/a Ki(nM) = 240.0
IC50(nM) = 1500.0
123 Q16539_GK4 GK4 DB07834 21078798 CHEMBL273158 N-(cyclopropylmethyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide n/a Ki(nM) = 480.0
IC50(nM) = 3000.0
124 Q16539_GK5 GK5 DB07835 24856363 CHEMBL478649 N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide n/a Ki(nM) = 9.0
IC50(nM) = 18.0
125 Q16539_GK6 GK6 n/a 24856364 CHEMBL476351 N-{4'-[(cyclopropylmethyl)carbamoyl]-6-methylbiphenyl-3-yl}-2-morpholin-4-ylpyridine-4-carboxamide n/a
126 Q16539_GOL GOL DB09462 753 CHEMBL692 GLYCEROL n/a
127 Q16539_GXH GXH n/a 137796768 n/a 3-(2,5-dimethoxyphenyl)-~{N}-[4-[4-(4-fluorophenyl)-2-(2-phenylhydrazinyl)-1,3-thiazol-5-yl]pyridin-2-yl]propanamide n/a
128 Q16539_HB9 HB9 n/a 129900106 CHEMBL4092372 ~{N}-[2,4-bis(fluoranyl)-5-[[14-(2-hydroxyethylcarbamoyl)-2-oxidanylidene-6-tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaenyl]amino]phenyl]thiophene-2-carboxamide n/a
129 Q16539_HIZ HIZ n/a 44462701 n/a 1-{4-[(1S)-1-amino-2-(benzyloxy)ethyl]-1,3-thiazol-2-yl}-3-(3-chloro-4-fluorophenyl)urea n/a
130 Q16539_HYK HYK n/a 54756452 CHEMBL5173417 1-[5-~{tert}-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[(1~{S},4~{S})-4-[(3-propan-2-yl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)oxy]-1,2,3,4-tetrahydronaphthalen-1-yl]urea n/a
131 Q16539_HYW HYW n/a 54756455 CHEMBL5206328 1-[5-~{tert}-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[(1~{S},4~{R})-4-[(3-propan-2-yl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)oxy]-1,2,3,4-tetrahydronaphthalen-1-yl]urea n/a
132 Q16539_I2O I2O n/a 44251218 CHEMBL1800911 N-cyclopropyl-4-methyl-3-(2'-oxo-1',2'-dihydrospiro[cyclopentane-1,3'-indol]-6'-yl)benzamide n/a
133 Q16539_I39 I39 n/a 24745781 CHEMBL551717 [3-amino-2-(2-methylphenyl)-1-oxidopyridin-4-yl](2,4-difluorophenyl)methanone n/a
134 Q16539_I45 I45 DB07941 22049997 CHEMBL1088751 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamide n/a Ki(nM) = 2.9
IC50(nM) = 1.1
Kd(nM) = 2.5
135 Q16539_I46 I46 DB07942 42647299 n/a 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine n/a
136 Q16539_I47 I47 DB07943 9865587 CHEMBL1090173 2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol n/a
137 Q16539_IPK IPK n/a 20883691 n/a 2-({4-[(4-benzylpiperidin-1-yl)carbonyl]benzyl}sulfanyl)-3H-imidazo[4,5-c]pyridine n/a
138 Q16539_IRG IRG n/a 70678412 n/a N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine n/a
139 Q16539_J8S J8S n/a 1126109 CHEMBL1450144 (4-benzylpiperidin-1-yl)[2-methoxy-4-(methylsulfanyl)phenyl]methanone n/a
140 Q16539_J9G J9G n/a 137796775 n/a 3-benzyl-6-[(2,4-difluorophenyl)amino]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one n/a
141 Q16539_JZJ JZJ n/a 44462703 CHEMBL1233784 (3S)-3-[4-(4-bromophenyl)-1H-imidazol-2-yl]-1,2,3,4-tetrahydroisoquinoline n/a
142 Q16539_KQ7 KQ7 n/a 44472896 n/a N-(2-methyl-5-{[(2-morpholin-4-ylpyridin-4-yl)carbonyl]amino}phenyl)-6-({2-[(2S)-1-methylpyrrolidin-2-yl]ethyl}amino)py ridine-3-carboxamide n/a
143 Q16539_L09 L09 DB08064 5326866 CHEMBL191598 N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA n/a IC50(nM) = 350.0
144 Q16539_L10 L10 DB01807 n/a n/a N-[(3Z)-5-TERT-BUTYL-2-PHENYL-1,2-DIHYDRO-3H-PYRAZOL-3-YLIDENE]-N'-(4-CHLOROPHENYL)UREA n/a
145 Q16539_L11 L11 DB08068 46937120 n/a N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO- n/a
146 Q16539_L12 L12 DB01953 27934 CHEMBL193156 3-(2-PYRIDIN-4-YLETHYL)-1H-INDOLE inhibitor IC50(nM) = 35000.0
147 Q16539_L51 L51 n/a 44462687 CHEMBL570427 1-{3-[(6-aminoquinolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea n/a
148 Q16539_L9G L9G n/a 11632560 n/a 3-{6-[2-(2,4-difluorophenyl)ethyl][1,2,4]triazolo[4,3-a]pyridin-3-yl}-4-methylbenzamide n/a
149 Q16539_LB5 LB5 n/a 139030330 CHEMBL4574467 ~{N}-[(2~{S})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]-2-[[[1-(2-methylphenyl)pyrazol-4-yl]carbonylamino]methyl]-1,3-thiazole-5-carboxamide n/a
150 Q16539_LB8 LB8 n/a 139030332 CHEMBL4465031 ~{N}-[5-[[(2~{S})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]carbamoyl]-2-methyl-phenyl]-1-phenyl-5-(trifluoromethyl)pyrazole-4-carboxamide n/a
151 Q16539_LBB LBB n/a 139030331 CHEMBL4476320 ~{N}-[5-[[(2~{S})-1-azanyl-4-cyclohexyl-1-oxidanylidene-butan-2-yl]carbamoyl]-2-methyl-phenyl]-1-(2-methylphenyl)pyrazole-4-carboxamide n/a
152 Q16539_LBE LBE n/a 139030333 CHEMBL4436748 5-azanyl-~{N}-[[4-(3-cyclohexylpropylcarbamoyl)phenyl]methyl]-1-phenyl-pyrazole-4-carboxamide n/a
153 Q16539_LGF LGF n/a 16758225 n/a 1-[5-[[3-[2,4-bis(fluoranyl)phenyl]-6,8-dihydro-5~{H}-imidazo[1,5-a]pyrazin-7-yl]carbonyl]-6-methoxy-1~{H}-pyrrolo[2,3-b]pyridin-3-yl]-2-[(3~{R})-3-oxidanylpyrrolidin-1-yl]ethane-1,2-dione n/a
154 Q16539_LHJ LHJ n/a 25118220 CHEMBL1091199 N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-4-methylbenzamide n/a
155 Q16539_LI2 LI2 DB08091 5326868 CHEMBL365776 3-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDE n/a IC50(nM) = 630.0
156 Q16539_LI3 LI3 DB08092 5326870 CHEMBL195450 3-FLUORO-N-1H-INDOL-5-YL-5-MORPHOLIN-4-YLBENZAMIDE n/a IC50(nM) = 162000.0
157 Q16539_LI4 LI4 DB08093 5326871 CHEMBL195393 3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE inhibitor IC50(nM) = 44000.0
158 Q16539_LM3 LM3 n/a 71464711 CHEMBL4646628 N,N-dimethyl-6-(naphthalen-1-yl)-5-(pyridin-4-yl)pyridazin-3-amine n/a
159 Q16539_LM4 LM4 n/a 71464710 CHEMBL4648060 N,N-dimethyl-6-(naphthalen-2-yl)-5-(pyridin-4-yl)pyridazin-3-amine n/a
160 Q16539_MES MES DB03814 78165;4478249; CHEMBL1234276 2-(N-MORPHOLINO)-ETHANESULFONIC ACID n/a
161 Q16539_MG MG n/a 888 n/a MAGNESIUM ION n/a
162 Q16539_MIH MIH n/a 24899987 CHEMBL1738839 8-(2,6-dichlorophenyl)-4-(2,4-difluorophenyl)-2-piperidin-4-yl-1,7-naphthyridine 7-oxide n/a
163 Q16539_MKP MKP n/a 50943378 n/a 3-(3-tert-butyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-6-yl)-4-methyl-N-(1,2-oxazol-3-yl)benzamide n/a
164 Q16539_MSQ MSQ DB02984 1714 CHEMBL29641 4-[3-METHYLSULFANYLANILINO]-6,7-DIMETHOXYQUINAZOLINE n/a
165 Q16539_MWL MWL n/a 24743826 CHEMBL4632881 3-phenyl-4-(pyridin-4-yl)-6-[4-(pyrimidin-2-yl)piperazin-1-yl]pyridazine n/a
166 Q16539_N3F N3F n/a 11737779 CHEMBL152596 {4-[(2-aminophenyl)amino]phenyl}(phenyl)methanone n/a
167 Q16539_N4D N4D DB08242 23400214 CHEMBL410668 N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide n/a IC50(nM) = 10.0
168 Q16539_NA NA n/a 923 n/a SODIUM ION n/a
169 Q16539_NAR NAR DB03467 439246 CHEMBL9352 NARINGENIN n/a
170 Q16539_NK0 NK0 n/a 10048045 CHEMBL1807446 3-[(6-benzoyl-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-yl)amino]-N-cyclopropyl-4-methylbenzamide n/a
171 Q16539_NQB NQB n/a 11373432 CHEMBL2031465 N-CYCLOPROPYL-4-METHYL-3-[6-(4-METHYLPIPERAZIN-1-YL)-4-OXIDANYLIDENE-QUINAZOLIN-3-YL]BENZAMIDE n/a
172 Q16539_OCG OCG n/a 46943424 CHEMBL1234931 5-amino-N-[5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl]-1-phenyl-1H-pyrazole-4-carboxamide n/a
173 Q16539_OE8 OE8 n/a 145994863 CHEMBL4740565 5-azanyl-~{N}-[[4-[[(2~{S})-4-cyclohexyl-1-[(4-fluorophenyl)amino]-1-oxidanylidene-butan-2-yl]carbamoyl]phenyl]methyl]-1-phenyl-pyrazole-4-carboxamide n/a
174 Q16539_P0F P0F n/a 130429150 CHEMBL4079354 3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-4H-1,2,4-triazol-3-yl)phenol n/a
175 Q16539_P36 P36 n/a 10126288 CHEMBL1095447 1-benzyl-4-(benzyloxy)-3-bromopyridin-2(1H)-one n/a
176 Q16539_P37 P37 DB08349 42647297 CHEMBL559401 N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide n/a IC50(nM) = 3.2
177 Q16539_P38 P38 n/a 49867465 n/a 5-methyl-4-[(2-methyl-5-{[(2-morpholin-4-ylpyridin-4-yl)carbonyl]amino}phenyl)amino]-N-(1-phenylethenyl)pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide n/a
178 Q16539_P39 P39 n/a 24764438 CHEMBL408150 5-methyl-4-[(2-methyl-5-{[(3-morpholin-4-ylphenyl)carbonyl]amino}phenyl)amino]-N-[(1S)-1-phenylethyl]pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide n/a
179 Q16539_P40 P40 DB08351 24963046 CHEMBL494072 N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide n/a IC50(nM) = 0.9
180 Q16539_P41 P41 DB08352 24755476 CHEMBL257341 6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine n/a IC50(nM) = 6.4
181 Q16539_P66 P66 n/a 44631836 CHEMBL1082158 4-chloro-N-cyclopropyl-3-{[1-(2,6-difluorophenyl)-1H-pyrazolo[3,4-d]pyridazin-4-yl]amino}benzamide n/a
182 Q16539_PEG PEG n/a 8117 CHEMBL1235226 DI(HYDROXYETHYL)ETHER n/a
183 Q16539_PO2 PO2 DB04053 183145 n/a HYPOPHOSPHITE n/a
184 Q16539_PP0 PP0 n/a 20879070 n/a ethyl 4-[(4-benzylpiperazin-1-yl)carbonyl]-1-ethyl-3,5-dimethyl-1H-pyrrole-2-carboxylate n/a
185 Q16539_PQA PQA DB08423 5327066 n/a [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE n/a
186 Q16539_PQB PQB DB08424 5327067 CHEMBL203567 [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE inhibitor IC50(nM) = 180.0
187 Q16539_QC0 QC0 n/a 56962313 CHEMBL2031238 N-[4-METHYL-3-[6-(4-METHYLPIPERAZIN-1-YL)-4-OXIDANYLIDENE-QUINAZOLIN-3-YL]PHENYL]FURAN-3-CARBOXAMIDE n/a
188 Q16539_R24 R24 n/a 44462688 CHEMBL568874 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-{3-[(6-nitroquinolin-4-yl)amino]phenyl}urea n/a
189 Q16539_R39 R39 n/a 10972838 CHEMBL101035 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[4-(2-morpholin-4-ylethoxy)phenyl]urea n/a
190 Q16539_R48 R48 n/a 42608443 CHEMBL569943 1-{3-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea n/a
191 Q16539_R49 R49 n/a 44462686 CHEMBL570904 1-{4-[(6-aminoquinolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1H-pyrazol-5-yl]urea n/a
192 Q16539_RO6 RO6 n/a n/a CHEMBL1235713 3-(2-chlorophenyl)-7-[(trans-4-hydroxycyclohexyl)amino]-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one n/a
193 Q16539_SB0 SB0 n/a n/a CHEMBL97162 trans-4-[4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)-1H-imidazol-1-yl]cyclohexanol n/a
194 Q16539_SB2 SB2 DB08521 9543416 n/a 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE n/a
195 Q16539_SB4 SB4 DB04338 5164 CHEMBL274064 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE inhibitor IC50(nM) = 19.0
196 Q16539_SB5 SB5 DB03980 5172 CHEMBL590753 4-(FLUOROPHENYL)-1-CYCLOPROPYLMETHYL-5-(2-AMINO-4-PYRIMIDINYL)IMIDAZOLE inhibitor IC50(nM) = 25.0
197 Q16539_SB6 SB6 DB08522 5171 CHEMBL96741 4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE inhibitor IC50(nM) = 160.0
198 Q16539_SO4 SO4 DB14546 1117 n/a SULFATE ION n/a
199 Q16539_TZY TZY DB04797 5289514 CHEMBL194322 6-[4-(4-FLUOROPHENYL)-1,3-OXAZOL-5-YL]-3-ISOPROPYL[1,2,4]TRIAZOLO[4,3-A]PYRIDINE inhibitor IC50(nM) = 5.0
200 Q16539_VVT VVT n/a 87264666 CHEMBL4646517 6-chloro-3-phenyl-4-(pyridin-4-yl)pyridazine n/a
201 Q16539_WBT WBT DB08730 5326869 CHEMBL193264 3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE n/a IC50(nM) = 340.0
202 Q16539_XI2 XI2 n/a 44517635 CHEMBL1236810 6-(2,4-difluorophenoxy)-N-[(1R)-1-methyl-2-(methylsulfonyl)ethyl]-1H-pyrazolo[3,4-d]pyrimidin-3-amine n/a
203 Q16539_YIS YIS DB12138 11714580 CHEMBL1938400 1-[3-tert-butyl-1-(3-chloro-4-hydroxyphenyl)-1H-pyrazol-5-yl]-3-{2-[(3-{2-[(2-hydroxyethyl)sulfanyl]phenyl}[1,2,4]triazolo[4,3-a]pyridin-6-yl)sulfanyl]benzyl}urea n/a
204 Q16539_YIW YIW n/a 53497556 CHEMBL1938736 1-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea n/a
205 Q16539_YIX YIX n/a 9842281 CHEMBL1938764 1-ethyl-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea n/a
206 Q16539_Z83 Z83 n/a 51035421 CHEMBL1738942 (4-{3-tert-butyl-5-[(1,3-thiazol-2-ylcarbamoyl)amino]-1H-pyrazol-1-yl}phenyl)acetic acid n/a
207 Q16539_Z84 Z84 n/a 51035420 CHEMBL1738943 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-{4-[2-(pyridin-4-ylmethoxy)ethyl]-1,3-thiazol-2-yl}urea n/a
208 Q16539_Z85 Z85 n/a 51035419 CHEMBL1738944 1-{4-[2-(benzyloxy)ethyl]-1,3-thiazol-2-yl}-3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea n/a
209 Q16539_Z86 Z86 n/a 51035418 CHEMBL1738945 (4-{5-[({4-[2-(benzyloxy)ethyl]-1,3-thiazol-2-yl}carbamoyl)amino]-3-tert-butyl-1H-pyrazol-1-yl}phenyl)acetic acid n/a
210 Q16539_Z87 Z87 n/a 51035417 CHEMBL1738946 1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-(1,3-thiazol-2-yl)urea n/a
211 Q16539_ZN ZN n/a 32051 CHEMBL1236970 ZINC ION n/a
212 Q16539_SS6 SS6 n/a 42608444 CHEMBL497615 1-{3-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1H-pyrazol-5-yl]urea n/a
213 Q16539_STI STI DB00619 5291 CHEMBL941 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE n/a IC50(nM) = 13700.0
Kd(nM) = 3162.0
214 Q16539_T75 T75 DB16108 9952773 CHEMBL363648 TAK-715 n/a
215 Q16539_DB05470 n/a DB05470 n/a n/a VX-702 modulator
216 Q16539_LIB LIB DB08095 6540299 CHEMBL379760 3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA n/a IC50(nM) = 92.0
217 Q16539_LID LID DB08096 6852209 CHEMBL425616 8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM n/a
218 Q16539_LIE LIE DB08097 9543517 CHEMBL380373 2-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINE n/a
219 Q16539_PGJ PGJ DB08395 4369443 CHEMBL371491 2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE n/a IC50(nM) = 460.0
220 Q16539_DB08521 n/a DB08521 n/a n/a 4-[4-(4-Fluorophenyl)-2-[4-[(R)-methylsulfinyl]phenyl]-1H-imidazol-5-yl]pyridine n/a
221 Q16539_2RC 2RC DB12010 11671467 CHEMBL2103830 Fostamatinib inhibitor