Gene name: TUBA1B
Protein name: Tubulin alpha-1B chain
List of molecules and drugs that interact with protein Q2XVP4
| # | DrugDomain Data | PBD ligand | DrugBank Accession | PubChem | ChEMBL | Name | Drug action | Affinity data |
|---|---|---|---|---|---|---|---|---|
| 1 | Q2XVP4_4Q5 | 4Q5 | n/a | 11542188 | CHEMBL2103835 | N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino}-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl}-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide | n/a | |
| 2 | Q2XVP4_4SL | 4SL | n/a | 44393128 | CHEMBL185116 | N,beta,beta-trimethyl-L-phenylalanyl-N-[(3S,4Z)-5-carboxy-2-methylhex-4-en-3-yl]-N,3-dimethyl-L-valinamide | n/a | |
| 3 | Q2XVP4_55Q | 55Q | n/a | 121232374 | n/a | (2R,4R)-4-{[(2-{(1R,3R)-1-(acetyloxy)-4-methyl-3-[methyl(N-{[(2S)-1-methylpiperidin-2-yl]carbonyl}-D-isoleucyl)amino]pentyl}-1,3-thiazol-4-yl)carbonyl]amino}-2-methyl-5-phenylpentanoic acid | n/a | |
| 4 | Q2XVP4_7LG | 7LG | n/a | 131801392 | n/a | (2~{S},4~{R})-4-[[2-[(1~{R},3~{R})-1-acetyloxy-3-[hexyl-[(2~{S},3~{S})-3-methyl-2-[[(2~{R})-1-methylpiperidin-2-yl]carbonylamino]pentanoyl]amino]-4-methyl-pentyl]-1,3-thiazol-4-yl]carbonylamino]-5-(4-fluorophenyl)-2-methyl-pentanoic acid | n/a | |
| 5 | Q2XVP4_7Q7 | 7Q7 | n/a | 122195227 | CHEMBL3633360 | 2-(1H-indol-4-yl)-4-(3,4,5-trimethoxyphenyl)-1H-imidazo[4,5-c]pyridine | n/a | |
| 6 | Q2XVP4_88U | 88U | DB05585 | 11414799 | CHEMBL492399 | N-(4-methoxyphenyl)-N,2-dimethyl-quinazolin-4-amine | n/a | |
| 7 | Q2XVP4_890 | 890 | n/a | 132992905 | CHEMBL4591592 | 4-[(3-azanyl-4-methoxy-phenyl)-methyl-amino]chromen-2-one | n/a | |
| 8 | Q2XVP4_89C | 89C | n/a | 134163558 | CHEMBL4444361 | 4-[(4-methoxy-3-oxidanyl-phenyl)-methyl-amino]chromen-2-one | n/a | |
| 9 | Q2XVP4_8WU | 8WU | n/a | 71653040 | CHEMBL2336890 | (E)-1-(5-methoxy-2,2-dimethyl-chromen-8-yl)-3-(4-methoxy-3-oxidanyl-phenyl)prop-2-en-1-one | n/a | |
| 10 | Q2XVP4_8X0 | 8X0 | n/a | 66573474 | CHEMBL2041121 | (E)-1-(5-methoxy-2,2-dimethyl-chromen-8-yl)-3-(4-methoxyphenyl)prop-2-en-1-one | n/a | |
| 11 | Q2XVP4_96C | 96C | n/a | 137319628 | CHEMBL4295060 | 4-(4-ethoxyphenyl)-1-methyl-3-(3,4,5-trimethoxyphenyl)-1H-pyrazole | n/a | |
| 12 | Q2XVP4_9LX | 9LX | n/a | 86280647 | CHEMBL3780099 | 2-(6-fluoro-3-{[(4-methoxyphenyl)methyl]amino}imidazo[1,2-a]pyridin-2-yl)phenol | n/a | |
| 13 | Q2XVP4_9WR | 9WR | n/a | 138857390 | CHEMBL4468642 | [6-(3-hydroxy-4-methylphenyl)pyridin-2-yl](3,4,5-trimethoxyphenyl)methanone | n/a | |
| 14 | Q2XVP4_ACP | ACP | DB03909 | 91532 | CHEMBL133463 | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | n/a | |
| 15 | Q2XVP4_AEU | AEU | n/a | 56666556 | CHEMBL1808759 | N-[(3-phenoxyphenyl)methyl]-9H-beta-carbolin-3-amine | n/a | |
| 16 | Q2XVP4_AEX | AEX | n/a | 101402473 | CHEMBL5083915 | N-butyl-9H-beta-carbolin-3-amine | n/a | |
| 17 | Q2XVP4_AF6 | AF6 | n/a | 14146439 | CHEMBL1668726 | N-benzyl-9H-beta-carbolin-3-amine | n/a | |
| 18 | Q2XVP4_BG0 | BG0 | DB12925 | 23649181 | CHEMBL2103852 | (4R)-2,7,8-triamino-4-(3-bromo-4,5-dimethoxyphenyl)-4H-1-benzopyran-3-carbonitrile | n/a | |
| 19 | Q2XVP4_CA | CA | n/a | 271 | n/a | CALCIUM ION | n/a | |
| 20 | Q2XVP4_CL | CL | n/a | 312 | n/a | CHLORIDE ION | n/a | |
| 21 | Q2XVP4_DJ9 | DJ9 | n/a | 122195228 | CHEMBL3633361 | 2-(1H-indol-6-yl)-4-(3,4,5-trimethoxyphenyl)-1H-imidazo[4,5-c]pyridine | n/a | |
| 22 | Q2XVP4_DMS | DMS | DB01093 | 679 | CHEMBL504 | DIMETHYL SULFOXIDE | n/a | |
| 23 | Q2XVP4_DO6 | DO6 | n/a | 24786555 | CHEMBL1823147 | (6-methoxy-2-methyl-7-oxidanyl-1-benzofuran-3-yl)-(3,4,5-trimethoxyphenyl)methanone | n/a | |
| 24 | Q2XVP4_E3Y | E3Y | n/a | 134611708 | CHEMBL4102788 | 2-chloro-4-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)pyrido[2,3-d]pyrimidine | n/a | |
| 25 | Q2XVP4_E44 | E44 | n/a | 134611709 | CHEMBL4067605 | 2-chloro-4-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)pyrido[3,2-d]pyrimidine | n/a | |
| 26 | Q2XVP4_E9Y | E9Y | n/a | 134611711 | CHEMBL4095734 | 1-(3,6-dimethyl[1,2]oxazolo[5,4-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline | n/a | |
| 27 | Q2XVP4_EDO | EDO | n/a | 174 | CHEMBL457299 | 1,2-ETHANEDIOL | n/a | |
| 28 | Q2XVP4_ERR | ERR | n/a | 155804414 | CHEMBL4741004 | 2-(1-methylindol-5-yl)-7-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a]pyrimidine | n/a | |
| 29 | Q2XVP4_ERX | ERX | n/a | 155804415 | CHEMBL4744318 | 2-(4-methylphenyl)-7-(3,4,5-trimethoxyphenyl)pyrazolo[1,5-a]pyrimidine | n/a | |
| 30 | Q2XVP4_FUO | FUO | n/a | 155925939 | CHEMBL5088088 | 2-[5-[4-[2-[4-(2-cyclopropylethanoyl)piperazin-1-yl]ethoxy]phenyl]pyridin-2-yl]-N-(phenylmethyl)ethanamide | n/a | |
| 31 | Q2XVP4_FW9 | FW9 | n/a | 11210285 | CHEMBL4303671 | N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine | n/a | |
| 32 | Q2XVP4_G2P | G2P | DB03532 | 449108;5288325;135440070; | CHEMBL1232908 | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | n/a | |
| 33 | Q2XVP4_G2X | G2X | DB12533 | 11488110 | CHEMBL1182714 | 6-[2,6-bis(fluoranyl)-4-[3-(methylamino)propoxy]phenyl]-5-chloranyl-N-[(2S)-1,1,1-tris(fluoranyl)propan-2-yl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine | n/a | |
| 34 | Q2XVP4_G70 | G70 | n/a | 156587312 | n/a | (2~{S},4~{S})-4-[[2-[(1~{R},3~{R})-1-acetyloxy-4-methyl-3-[[(2~{S},3~{S})-3-methyl-2-[[(2~{R})-1-methylpiperidin-2-yl]carbonylamino]pentanoyl]amino]pentyl]-1,3-thiazol-4-yl]carbonylamino]-5-cyclohexyl-2-methyl-pentanoic acid | n/a | |
| 35 | Q2XVP4_G8K | G8K | n/a | 69038102 | CHEMBL4591755 | [2-(1H-indol-4-yl)-1H-imidazol-4-yl](3,4,5-trimethoxyphenyl)methanone | n/a | |
| 36 | Q2XVP4_G9K | G9K | n/a | 134814244 | CHEMBL4175942 | [2-(1H-indol-3-yl)-1H-imidazol-4-yl](8-methoxy-1,4-benzodioxin-6-yl)methanone | n/a | |
| 37 | Q2XVP4_GDF | GDF | n/a | 73265388 | CHEMBL3545879 | Vinorelbine | n/a | |
| 38 | Q2XVP4_GDP | GDP | DB04315 | 8977;5280316;135398619; | CHEMBL384759 | GUANOSINE-5'-DIPHOSPHATE | n/a | |
| 39 | Q2XVP4_GK9 | GK9 | n/a | 134611710 | CHEMBL4095025 | 1-(2-chlorofuro[3,2-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline | n/a | |
| 40 | Q2XVP4_GOL | GOL | DB09462 | 753 | CHEMBL692 | GLYCEROL | n/a | |
| 41 | Q2XVP4_GSP | GSP | DB01864 | 37792;444121;5280465;135398675;135450576; | CHEMBL1204628 | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | n/a | |
| 42 | Q2XVP4_GTP | GTP | DB04137 | 6830;5280317;135398633; | CHEMBL1233147 | GUANOSINE-5'-TRIPHOSPHATE | n/a | |
| 43 | Q2XVP4_GWC | GWC | n/a | 168059288 | n/a | 2-chloranyl-5-fluoranyl-N-(4-methoxyphenyl)-N-methyl-quinazolin-4-amine | n/a | |
| 44 | Q2XVP4_GX5 | GX5 | n/a | 168059287 | n/a | 2-chloranyl-N-(4-methoxyphenyl)-N-methyl-pyrido[3,2-d]pyrimidin-4-amine | n/a | |
| 45 | Q2XVP4_GXI | GXI | n/a | 168059286 | n/a | 2-chloranyl-7-fluoranyl-N-(4-methoxyphenyl)-N-methyl-quinazolin-4-amine | n/a | |
| 46 | Q2XVP4_GY2 | GY2 | n/a | 168059289 | n/a | 2-chloranyl-6-fluoranyl-N-(4-methoxyphenyl)-N-methyl-quinazolin-4-amine | n/a | |
| 47 | Q2XVP4_H0U | H0U | n/a | 46847888 | n/a | ~{N}-[5-(5-cyanothiophen-2-yl)-2-methyl-phenyl]-4-methyl-benzenesulfonamide | n/a | |
| 48 | Q2XVP4_H1C | H1C | n/a | 26596 | CHEMBL528271 | methyl ~{N}-(5-butyl-1~{H}-benzimidazol-2-yl)carbamate | n/a | |
| 49 | Q2XVP4_H1F | H1F | n/a | 56944939 | n/a | 5-phenyl-3-(3,4,5-trimethoxyphenyl)-3,4-dihydropyrazole-2-carbothioamide | n/a | |
| 50 | Q2XVP4_H1O | H1O | n/a | 156619925 | CHEMBL4852240 | 2-(1-methylindol-4-yl)-7-(3,4,5-trimethoxyphenyl)-1~{H}-benzimidazole | n/a | |
| 51 | Q2XVP4_HOS | HOS | n/a | 6438581 | CHEMBL446991 | Phomopsin A | n/a | |
| 52 | Q2XVP4_IC1 | IC1 | DB03083 | 5288600 | CHEMBL489156 | 3-[(2,4,6-TRIMETHOXY-PHENYL)-METHYLENE]-INDOLIN-2-ONE | n/a | |
| 53 | Q2XVP4_IMD | IMD | DB03366 | 444234;4434133;21983501; | n/a | IMIDAZOLE | n/a | |
| 54 | Q2XVP4_IUK | IUK | n/a | 139369407 | CHEMBL5190568 | 4-methyl-3-[(4-methylphenyl)sulfonylamino]-~{N}-[(6-methylpyridin-3-yl)methyl]benzamide | n/a | |
| 55 | Q2XVP4_J6L | J6L | n/a | 156793 | CHEMBL3311038 | 8,8-dimethyl-3-(2,4,5-trimethoxyphenyl)pyrano[2,3-f]chromen-4-one | n/a | |
| 56 | Q2XVP4_J6R | J6R | n/a | 163196895 | n/a | (2S,4R)-5-(4-fluorophenyl)-2-methyl-4-[[2-[(1R,3R)-4-methyl-3-[5-methylhexyl-[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidin-2-yl]carbonylamino]pentanoyl]amino]-1-oxidanyl-pentyl]-1,3-thiazol-4-yl]carbonylamino]pentanoic acid | n/a | |
| 57 | Q2XVP4_J7S | J7S | n/a | 138857407 | n/a | 4-(2-chloropyrido[2,3-d]pyrimidin-4-yl)-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one | n/a | |
| 58 | Q2XVP4_JEL | JEL | n/a | 154632611 | CHEMBL5081610 | N-[[3-(1,3-benzodioxol-5-yloxy)phenyl]methyl]-9H-pyrido[3,4-b]indol-3-amine | n/a | |
| 59 | Q2XVP4_JUL | JUL | n/a | 166090160 | n/a | 7-methoxy-4-[2-(morpholin-4-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-3,4-dihydroquinoxalin-2(1H)-one | n/a | |
| 60 | Q2XVP4_JV9 | JV9 | n/a | 166090152 | n/a | 7-methoxy-4-[2-(methylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-3,4-dihydroquinoxalin-2(1H)-one | n/a | |
| 61 | Q2XVP4_JVI | JVI | n/a | 166090129 | n/a | 4-[2-(ethylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one | n/a | |
| 62 | Q2XVP4_JVR | JVR | n/a | 166090131 | n/a | 4-[2-(cyclopropylamino)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one | n/a | |
| 63 | Q2XVP4_KB4 | KB4 | n/a | 139592925 | CHEMBL4520878 | 4-(2-chloropyrido[3,2-d]pyrimidin-4-yl)-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one | n/a | |
| 64 | Q2XVP4_KUM | KUM | DB16462 | 53379371 | CHEMBL2163631 | [2-(1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)methanone | n/a | |
| 65 | Q2XVP4_LOC | LOC | DB01394 | 6167 | CHEMBL107 | N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide | n/a | |
| 66 | Q2XVP4_LON | LON | DB13318 | 220401 | CHEMBL312862 | (7S)-1,2,3,10-tetramethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one | n/a | |
| 67 | Q2XVP4_LXL | LXL | n/a | 11351021 | CHEMBL552212 | 1-ethyl-3-[2-methoxy-4-(5-methyl-4-{[(1S)-1-(pyridin-3-yl)butyl]amino}pyrimidin-2-yl)phenyl]urea | n/a | |
| 68 | Q2XVP4_MES | MES | DB03814 | 78165;4478249; | CHEMBL1234276 | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | n/a | |
| 69 | Q2XVP4_MG | MG | n/a | 888 | n/a | MAGNESIUM ION | n/a | |
| 70 | Q2XVP4_MZK | MZK | n/a | 12000936 | CHEMBL1222153 | 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one | n/a | |
| 71 | Q2XVP4_NA | NA | n/a | 923 | n/a | SODIUM ION | n/a | |
| 72 | Q2XVP4_NV4 | NV4 | n/a | 131632973 | n/a | (5R,5aR,8aS,9R)-9-[(4H-1,2,4-triazol-3-yl)sulfanyl]-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydro-2H-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one | n/a | |
| 73 | Q2XVP4_O91 | O91 | n/a | 49787837 | CHEMBL1272023 | [2-(4-methylphenyl)-1H-imidazol-4-yl](3,4,5-trimethoxyphenyl)methanone | n/a | |
| 74 | Q2XVP4_O9B | O9B | n/a | 11286529;11862129; | n/a | (2~{R})-1-methylpiperidine-2-carboxylic acid | n/a | |
| 75 | Q2XVP4_O9H | O9H | n/a | n/a | n/a | [(1~{R},3~{R})-1-acetyloxy-1-[4-methanoyl-5-(2-phenylmethoxyethyl)-2,3-dihydro-1,3-thiazol-2-yl]-4-methyl-pentan-3-yl]-methyl-azanium | n/a | |
| 76 | Q2XVP4_O9K | O9K | n/a | 146691205 | n/a | [(1~{R},3~{R})-1-(4-methanoyl-1,3-thiazol-2-yl)-4-methyl-3-(methylamino)pentyl] ethanoate | n/a | |
| 77 | Q2XVP4_P6S | P6S | n/a | 2285 | n/a | benzyl hydrogen carbonate | n/a | |
| 78 | Q2XVP4_PEG | PEG | n/a | 8117 | CHEMBL1235226 | DI(HYDROXYETHYL)ETHER | n/a | |
| 79 | Q2XVP4_PGE | PGE | DB02327 | 8172 | CHEMBL1235259 | TRIETHYLENE GLYCOL | n/a | |
| 80 | Q2XVP4_PO4 | PO4 | DB14523 | 1061 | n/a | PHOSPHATE ION | n/a | |
| 81 | Q2XVP4_QW9 | QW9 | n/a | 138454919 | CHEMBL4550982 | [2-(4-methyl-1H-indol-3-yl)-1H-imidazol-5-yl](3,4,5-trimethoxyphenyl)methanone | n/a | |
| 82 | Q2XVP4_S40 | S40 | n/a | 139390983 | CHEMBL5169832 | 3-[(4-cyclopropylphenyl)sulfonylamino]-4-methyl-N-(pyridin-3-ylmethyl)benzamide | n/a | |
| 83 | Q2XVP4_SO4 | SO4 | DB14546 | 1117 | n/a | SULFATE ION | n/a | |
| 84 | Q2XVP4_TU2 | TU2 | n/a | 156583242 | CHEMBL5081479 | [3-fluoro-6-(3-hydroxy-4-methylphenyl)pyridin-2-yl](3,4,5-trimethoxyphenyl)methanone | n/a | |
| 85 | Q2XVP4_TU3 | TU3 | n/a | 156583241 | CHEMBL5074758 | [6-(3-hydroxy-4-methylphenyl)pyrazin-2-yl](3,4,5-trimethoxyphenyl)methanone | n/a | |
| 86 | Q2XVP4_VAL | VAL | DB00161 | 6287;6971018;88733505; | CHEMBL43068 | VALINE | n/a | |
| 87 | Q2XVP4_X3H | X3H | n/a | 101054774 | n/a | PIRONETIN | n/a | |
| 88 | Q2XVP4_Y50 | Y50 | n/a | 72188750 | CHEMBL3338195 | E-3-(3-azanyl-4-methoxy-phenyl)-1-(5-methoxy-2,2-dimethyl-chromen-8-yl)prop-2-en-1-one | n/a | |
| 89 | Q2XVP4_Y5J | Y5J | n/a | 156599521 | CHEMBL4876166 | 4-(2-chlorofuro[3,2-d]pyrimidin-4-yl)-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one | n/a | |
| 90 | Q2XVP4_Y5L | Y5L | n/a | 156599522 | CHEMBL4879163 | 4-(2-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one | n/a | |
| 91 | Q2XVP4_Y5M | Y5M | n/a | 156599523 | CHEMBL4855608 | 7-methoxy-4-(2-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-3,4-dihydroquinoxalin-2(1H)-one | n/a | |
| 92 | Q2XVP4_YJ4 | YJ4 | n/a | 156599543 | CHEMBL4871913 | 4-[2-(ethylamino)pyrido[3,2-d]pyrimidin-4-yl]-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one | n/a | |
| 93 | Q2XVP4_YJ7 | YJ7 | n/a | 156599542 | n/a | 4-(3,6-dimethyl[1,2]oxazolo[5,4-d]pyrimidin-4-yl)-7-methoxy-3,4-dihydroquinoxalin-2(1H)-one | n/a |