Q81R22 Q81R22_BACAN
Gene name: dfrA
Protein name: Dihydrofolate reductase (EC

List of molecules and drugs that interact with protein Q81R22

#	DrugDomain Data	PBD ligand	DrugBank Accession	PubChem	ChEMBL	Name	Drug action	Affinity data
1	Q81R22_31I	31I	n/a	78225950	n/a	(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(propan-2-yl)phthalazin-2(1H)-yl]prop-2-en -1-one	n/a
2	Q81R22_34R	34R	n/a	70699409	n/a	(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1R)-1-phenylphthalazin-2(1H)-yl]prop-2-en-1-one	n/a
3	Q81R22_34S	34S	n/a	70699408	n/a	(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-phenylphthalazin-2(1H)-yl]prop-2-en-1-one	n/a
4	Q81R22_35I	35I	n/a	70699412	n/a	(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(3,3,3-trifluoropropyl)phthalazin-2(1H)-yl ]prop-2-en-1-one	n/a
5	Q81R22_52I	52I	n/a	137348307	n/a	(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1R)-1-(2-methylpropyl)phthalazin-2(1H)-yl]prop-2 -en-1-one	n/a
6	Q81R22_52J	52J	n/a	70699417	n/a	(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(2-methylpropyl)phthalazin-2(1H)-yl]prop-2-en-1-one	n/a
7	Q81R22_53I	53I	n/a	70699415	n/a	(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1R)-1-(2-methylprop-1-en-1-yl)phthalazin-2(1H)-y l]prop-2-en-1-one	n/a
8	Q81R22_53J	53J	n/a	137348309	n/a	(2E)-3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-1-(2-methylprop-1-en-1-yl)phthalazin-2(1H)-y l]prop-2-en-1-one	n/a
9	Q81R22_5DR	5DR	n/a	52949513	CHEMBL1270533	6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine	n/a
10	Q81R22_5WA	5WA	n/a	45482199	CHEMBL575626	(1R)-3-(2,4-diamino-6-methylpyrimidin-5-yl)-1-(3,4,5-trimethoxyphenyl)prop-2-yn-1-ol	n/a
11	Q81R22_5WB	5WB	n/a	45482186	CHEMBL573811	5-[(3S)-3-methoxy-3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine	n/a
12	Q81R22_6DR	6DR	n/a	57149549	CHEMBL3526249	6-ethyl-5-{3-[2-methoxy-5-(pyridin-4-yl)phenyl]prop-1-yn-1-yl}pyrimidine-2,4-diamine	n/a
13	Q81R22_7DR	7DR	n/a	49788718	CHEMBL1270633	6-ethyl-5-[3-(5-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine	n/a
14	Q81R22_9DR	9DR	n/a	57149550	CHEMBL3219804	6-ethyl-5-{3-[3-methoxy-5-(pyridin-4-yl)phenyl]prop-1-yn-1-yl}pyrimidine-2,4-diamine	n/a
15	Q81R22_CA	CA	n/a	271	n/a	CALCIUM ION	n/a
16	Q81R22_CL	CL	n/a	312	n/a	CHLORIDE ION	n/a
17	Q81R22_EDO	EDO	n/a	174	CHEMBL457299	1,2-ETHANEDIOL	n/a
18	Q81R22_EKB	EKB	n/a	25138225	CHEMBL485959	6-ethyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-yl]pyrimidine-2,4-diamine	n/a
19	Q81R22_MTX	MTX	DB00563	126941	CHEMBL34259	METHOTREXATE	n/a
20	Q81R22_N22	N22	DB08234	25058133	CHEMBL485961	5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine	n/a
21	Q81R22_NAP	NAP	DB03461	5885;57525501;	CHEMBL295069	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	n/a
22	Q81R22_NDP	NDP	DB02338	5884;134821689;	CHEMBL407009	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	n/a
23	Q81R22_NI	NI	n/a	934	n/a	NICKEL (II) ION	n/a
24	Q81R22_PEG	PEG	n/a	8117	CHEMBL1235226	DI(HYDROXYETHYL)ETHER	n/a
25	Q81R22_RAR	RAR	n/a	42627761	CHEMBL1235617	5-(3,4-dimethoxy-5-{(1E)-3-oxo-3-[(1S)-1-propylphthalazin-2(1H)-yl]prop-1-en-1-yl}benzyl)pyrimidine-2,4-diamine	n/a
26	Q81R22_SO4	SO4	DB14546	1117	n/a	SULFATE ION	n/a
27	Q81R22_TOP	TOP	DB00440	5578	CHEMBL22	TRIMETHOPRIM	n/a