Attributes
UniProt ID
Protein Name
Fumarate hydratase class II
Ligand Name
~{N}-[2-methoxy-5-(1,2,4,5-tetrahydro-3-benzazepin-3-ylsulfonyl)phenyl]-2-(4-oxidanylidene-3~{H}-phthalazin-1-yl)ethanamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
QNCBSZJYYJGVGP-UHFFFAOYSA-N
SMILES
COc1ccc(cc1NC(=O)CC2=NNC(=O)c3c2cccc3)S(=O)(=O)N4CCc5ccccc5CC4
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
Interactive Mol* view for the current protein-molecule pair.
Structure: 6S88
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse6s88A1e6s88A2e6s88A3e6s88B1e6s88B2e6s88B3e6s88C1e6s88C2e6s88C3e6s88D1e6s88D2e6s88D3
ECOD domains from experimental PDB structures interacting with ligand L0K
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| A0A045IXZ8 | n/a | L0K | 6s88 | e6s88A1 | A:138-393 |
| A0A045IXZ8 | n/a | L0K | 6s88 | e6s88A2 | A:394-467 |
| A0A045IXZ8 | n/a | L0K | 6s88 | e6s88C1 | C:138-393 |
| A0A045IXZ8 | n/a | L0K | 6s88 | e6s88C2 | C:394-467 |