CITRIC ACID

A0A077EA44 — Hydroxymethylglutaryl-CoA reductase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB04272

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB04272

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
A0A077EA44	DB04272	7n7s	CIT	A	501	e7n7sA1	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	A	501	e7n7sB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	A	501	e7n7sB3	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	B	501	e7n7sA1	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	B	501	e7n7sA2	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	B	501	e7n7sB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	C	501	e7n7sC2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	C	501	e7n7sE1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	C	501	e7n7sE2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	D	501	e7n7sD1	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	D	501	e7n7sF1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	D	501	e7n7sF2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	E	501	e7n7sC1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	E	501	e7n7sC2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	E	501	e7n7sE1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	E	501	e7n7sE2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	F	502	e7n7sD1	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	F	502	e7n7sD2	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A077EA44	DB04272	7n7s	CIT	F	502	e7n7sF2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red