~{N}-[(1~{S},2~{R})-2-[[4-bromanyl-2-(methylcarbamoyl)-6-nitro-phenyl]amino]cyclohexyl]isoquinoline-4-carboxamide

A0A0A7E693 — 1A polyprotein

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand J7R

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand J7R

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
A0A0A7E693	n/a	7ene	J7R	A	401	e7eneA1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
A0A0A7E693	n/a	7ene	J7R	A	401	e7eneA2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
A0A0A7E693	n/a	7ene	J7R	A	401	e7eneB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
A0A0A7E693	n/a	7ene	J7R	B	401	e7eneA2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
A0A0A7E693	n/a	7ene	J7R	B	401	e7eneB1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
A0A0A7E693	n/a	7ene	J7R	B	401	e7eneB2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
A0A0A7E693	n/a	7ene	J7R	C	401	e7eneC1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
A0A0A7E693	n/a	7ene	J7R	C	401	e7eneC2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
A0A0A7E693	n/a	7ene	J7R	C	401	e7eneD2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
A0A0A7E693	n/a	7ene	J7R	D	401	e7eneC2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30
A0A0A7E693	n/a	7ene	J7R	D	401	e7eneD1	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain	Peptidase_C30
A0A0A7E693	n/a	7ene	J7R	D	401	e7eneD2	cradle loop barrel	RIFT-related	FMN-binding split barrel	Peptidase_C30