DrugDomain logoDrugDomain

(3~{R},4~{S})-1-(4-fluorophenyl)-3-[(3~{S})-3-(4-fluorophenyl)-3-oxidanyl-propyl]-4-(4-hydroxyphenyl)azetidin-2-one

A0A0C4DFX6 — NPC1 like intracellular cholesterol transporter 1

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB00973

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB00973

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
A0A0C4DFX6DB009737dfzH56A1306e7dfzA1Alpha-beta plaitsFerredoxin domains in multidrug efflux transporterMultidrug efflux transporter AcrB pore domainACR_tran
A0A0C4DFX6DB009737dfzH56A1306e7dfzA2Multidrug efflux transporter AcrB transmembrane domainMultidrug efflux transporter AcrB transmembrane domainMultidrug efflux transporter AcrB transmembrane domainPatched
A0A0C4DFX6DB009737dfzH56A1306e7dfzA3Multidrug efflux transporter AcrB transmembrane domainMultidrug efflux transporter AcrB transmembrane domainMultidrug efflux transporter AcrB transmembrane domainSterol-sensing
A0A0C4DFX6DB009737dfzH56A1306e7dfzA4Alpha-beta plaitsFerredoxin domains in multidrug efflux transporterMultidrug efflux transporter AcrB pore domainNPC1_MLD