3-HYDROXY-3-METHYLGLUTARYL-COENZYME A
A0A0D6J7E8 — 3-hydroxy-3-methylglutaryl coenzyme A reductase
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB03169
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand DB03169
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| A0A0D6J7E8 | DB03169 | 5wpk | HMG | A | 500 | e5wpkA2 | Alpha-beta plaits | HMG-CoA reductase | Substrate-binding domain of HMG-CoA reductase | HMG-CoA_red |
| A0A0D6J7E8 | DB03169 | 5wpk | HMG | A | 500 | e5wpkB1 | Alpha-beta plaits | HMG-CoA reductase | Substrate-binding domain of HMG-CoA reductase | HMG-CoA_red |
| A0A0D6J7E8 | DB03169 | 5wpk | HMG | A | 500 | e5wpkB3 | Alpha-beta plaits | HMG-CoA reductase | NAD-binding domain of HMG-CoA reductase | HMG-CoA_red |
| A0A0D6J7E8 | DB03169 | 5wpk | HMG | B | 502 | e5wpkA1 | Alpha-beta plaits | HMG-CoA reductase | NAD-binding domain of HMG-CoA reductase | HMG-CoA_red |
| A0A0D6J7E8 | DB03169 | 5wpk | HMG | B | 502 | e5wpkA2 | Alpha-beta plaits | HMG-CoA reductase | Substrate-binding domain of HMG-CoA reductase | HMG-CoA_red |
| A0A0D6J7E8 | DB03169 | 5wpk | HMG | B | 502 | e5wpkB1 | Alpha-beta plaits | HMG-CoA reductase | Substrate-binding domain of HMG-CoA reductase | HMG-CoA_red |
| A0A0D6J7E8 | DB03169 | 5wpk | HMG | B | 502 | e5wpkB2 | RuvA-C | HMG-CoA reductase flap domain | HMG-CoA reductase flap domain | n/a |